ASMS 2026: Photochemical Tissue Processing for MALDI Lipid Imaging

Kermit K. Murray and Kadeem O. Hayes Abstract A photochemical tissue region modification system for the MALDI imaging workflow. Introduction The standard MALDI imaging workflow comprises tissue sectioning, washing, and matrix application by spray or sublimation prior to analysis. We are developing a new instrument for tissue photochemical processing that produces biomarker compounds to facilitate …

Murray Group ASMS 2024 Presentations

MP 377 Laser Ablation Sampling and MALDI Imaging for Tissue Lipidomics TP 170 Deep Ultraviolet and Infrared Laser Ablation of Carbonic Anhydrase II TP 382 Photochemical Tissue Pre-processing for Matrix-Assisted Laser Desorption Ionization Imaging of Lipids TP 665 Deep Ultraviolet Laser Protein Footprinting WP 379 MALDI Imaging of Lipids using Long-chain n-Alkyl Primary Ammonium and …

ASMS 2024: Deep Ultraviolet and Infrared Laser Ablation of Carbonic Anhydrase II

Deep Ultraviolet and Infrared Laser Ablation of Carbonic Anhydrase II Neda Feizi1; Kadeem O Hayes2; Blessing Chisom Egbejiogu2; Kelcey B. Hines2; Kermit K. Murray2; Touradj Solouki11Baylor University, Waco, TX; 2Louisiana State University, Baton Rouge, LA IntroductionIntegrating ion mobility-mass spectrometry (IM-MS) with laser ablation (LA) holds great appeal for acquiring spatially resolved details on protein conformations. …