- by /u/gwernsubmitted by /u/gwern [link] [comments]
- by /u/nina_becHey everyone! I'm working on variant calling using FreeBayes, and I’m using the parallel version (freebayes-parallel) to call variants from a large set of BAM files (~321 genomes). I’m using freebayes-parallel to process the genomes in parallel. It’s splitting the reference genome into 100,000 base pair regions, and I’ve set it to use 36 threads. My questions are: Did I set up freebayes parallel correctly? Are there any mistakes or best practices I might be overlooking? I’d like to make this run faster. I’m working on an HPC system, so I have some flexibility in resource allocation. Are there any […]
- by /u/Alex-Row-2598submitted by /u/Alex-Row-2598 [link] [comments]
- by /u/mingomangomungoWoman-A and Woman-B’s brother have a Baby-X Woman-B and Woman-A’s brother have a Baby-Y What percentage related are Baby-X and Baby-Y??? I would think it would be a little more than cousins since its like double cousins lol. submitted by /u/mingomangomungo [link] [comments]
- I've been looking into ctDNA testing and came across Personalis' NeXT Personal assay. I'm curious how it compares to Natera's Signatera test, especially regarding accuracy, sensitivity, and overall clinical utility. Does anyone here have experience or insights into the strengths and weaknesses of Personalis vs. Signatera? I'd appreciate any technical or clinical perspectives you can share! [link] [comments]
- by /u/gwernsubmitted by /u/gwern [link] [comments]
- by /u/Amazingimportance61submitted by /u/Amazingimportance61 [link] [comments]
- by /u/funtasticjeyachandrMaybe I am just a dumb blonde, but can anyone help with downloading data sources of funcotator from Google cloud? submitted by /u/funtasticjeyachandr [link] [comments]
- by /u/Unusual-Seesaw547Hello everyone, I'm planning on getting a masters degree in either Genomics / Bioinformatics (in the UK) by 2027. I'm an international student so I was wondering if the job markets for these fields (bioinfo, genomics, biotech, pharma) are good in the UK. Or if I'm better off just getting my masters degree and moving elsewhere for better job opportunities. Thanks in advance submitted by /u/Unusual-Seesaw547 [link] [comments]
- by /u/nina_becHello, I’m working with a very large VCF file containing data from over 300 sequenced genomes. Some of these genomes are labeled as male and others as female. The males are haploid and the females are diploid, as I am working with bumblebees. After filtering the VCF file, I want to perform a PCA to see if the males and females cluster separately. This will help me check whether I’ve accidentally mislabeled any male genomes as female or vice versa. Currently, I’m working on a high-performance computing (HPC) system, but unfortunately, PLINK isn’t available as a module. Additionally, I cannot […]
- by /u/No-Mountain6715Hello everyone, I created a web application called GenAnalyzer, which simplifies the analysis of protein sequences, identifies mutations, and explores their potential links to genetic diseases. It integrates data from multiple sources like UniProt for protein sequences and ClinVar for mutation-disease associations. This project is my graduate project, and I would be really grateful if I could find someone who would use it and provide feedback. Your comments, ratings, and criticism would be greatly appreciated as they’ll help me improve the tool. You can check out the app here: GenAnalyzer Web App Feel free to leave any feedback, suggestions, or […]
- by /u/BubbleNutsPogHas anyone tried this company for help with taking guess work out of anxiety medication? submitted by /u/BubbleNutsPog [link] [comments]
Mass spectrometry websites, social media, journal feeds, and other links and items of interest to the mass spectrometry community.
