- by /u/micky_mickkNot an expert on this topic, but I recently came across a couple of companies now offering full-genome sequencing with IVF and embryo selection based on multiple factors – such as eye color, height, IQ, disease risk, etc. Attaching a link to an interview with one of them (the most factual and least promotional explanation of the technology I could find). Is what they are saying about accuracy plausible? Do you think this will be the norm, in the future? submitted by /u/micky_mickk [link] [comments]
- by /u/allemagnHi everyone, I am looking for a trustworthy company that offers whole genome sequencing outside the United States. Any recommendations? I asked questions to Dante Labs, but they did not reply, so I don't trust them to help if I have issues as a customer. There are two reasons for wanting a company outside the United States: currently, with the tariffs situation on low value items and living in Canada, it's too complicated to return the samples to an American company. I bought a kit from Sequencing but got it cancelled after our mailing company was requiring me to fill […]
- by /u/Mishita_maggosubmitted by /u/Mishita_maggo [link] [comments]
- by /u/Holodoxasubmitted by /u/Holodoxa [link] [comments]
- by /u/No_Hold_9560I guess I’m not the only one who hates tests that require blood samples, which usually involve painful pricks on the thumb. Recently, I came across a company called Sequencing.com, which offers a home-based DNA collection kit that allows users to collect their own samples through a simple mouth swab. Surprisingly, this single swab is enough to carry out various DNA tests, including Whole Genome Sequencing (WGS). I know the technology has been around for a while, but I’m sure there are many people like me who didn’t know that a mouth swab could be used for WGS. submitted by […]
- by /u/AdditionalMushroom13Hey r/genomics, I've been developing an open-source tool to make it easier to work with the outputs of modern pangenome assemblers, and I’d love to share it with the community. ## The Problem As pangenomics becomes more central to genomics research, we're increasingly working with complex variation graphs (often in .gfa format). While tools like odgi are fantastic on the command line, performing custom, fine-grained analysis—like iterating through paths or building novel statistical models—programmatically can be challenging. ## The Solution: odgi-ffi To address this, I built odgi-ffi, a Rust library that provides a safe and high-performance programming interface for odgi's […]
- by /u/BiomedicineInstitutehttps://ideas.lego.com/s/p:0ccb9c270ae54410852df2105bb993c8?s=w Biomedicine Institute of my friend reached almost 2000 supporters! I'm very grateful to everyone who voted! If you didn't, please, consider supporting it and sharing with your friends. Thank you very much! submitted by /u/BiomedicineInstitute [link] [comments]
- by /u/fugapkusubmitted by /u/fugapku [link] [comments]
- by /u/SympraxisWhen organisms that replicate sexually (eukaryotes) then dna is contributed from a male and female, recombined and then donated to offspring. Is there a very clear web based description of this process? I have seen a lot of YouTube videos but I find them very confusing, irrelevant and time wasting. They have all kinds of cartoonish simplifications and spend huge amounts of time droning on about hereditary diseases and other irrelevant things. I just want a direct and clear diagrammatic description of sexual reproduction of the genome. As I understand it the basic process is that both the egg and […]
- by /u/TigerEar0848Hi everyone! I have got my whole genome sequenced (NGS) through Nebula Genomics and got CRAM, CRAI and TBI files (~3GB). I would like to use my genome to find all the carrier status and potential genetic diseases (both polygenic and monogenic) in my genome. I have already used gene.iobio to look at some genes, but you cannot do it for all 20,000 genes at the same time, plus you need to look at each SNP individually and then go online to check every single one of them. Therefore, I want to write a code that will give me an […]
- by /u/Conscious_Sky3703So… a few years back I took part in the 1000 Genomes Project, I thought it would be a good idea to ask them for my data. I suspect I’ve got the MTHFR mutation (the one that messes with B12/folate/methylation), but honestly I wouldn’t know how to find it unless it jumped out at me waving a neon sign. (That’s why I’m doing this) They very kindly obliged. Now I have… 66.9 GB to download Apparently this is my “whole genome sequence,” but to me its going to look like alphabet soup (A, T, C, G, repeat x 3 billion). […]
- by /u/tinymagiciannThere is a lot more information encoded in DNA than proteins. And we have a lot more DNA sequencing data. So if protein models like alphafold can be really useful, DNA models can be even more useful There are four applications I’m excited about: State-specific promoters (CAR-T, AAV gene therapy, and ddRNAi drugs) Discover new disease-causing targets through in silico mutagenesis Resolving variants of unknown significance Biosecurity More of my thoughts can be found here https://www.aditharun.com/p/dna-foundation-models submitted by /u/tinymagiciann [link] [comments]
Mass spectrometry websites, social media, journal feeds, and other links and items of interest to the mass spectrometry community.
