- by /u/manju_tsubmitted by /u/manju_t [link] [comments]
- by /u/A3_Research_Assistsubmitted by /u/A3_Research_Assist [link] [comments]
- by /u/Fresh_Fault_3614Over the past year I've noticed that reading papers has almost become a separate project from the actual research. By the time I finish going through a few studies on a workflow or analysis method, there are already several newer papers that seem worth looking at as well. It sometimes feels like the challenge isn't finding information anymore but it's deciding what deserves your attention first and what can safely wait. I would like to know how others handle this. Do you have a system for keeping up with new publications without feeling like you're constantly behind, or do you […]
- by /u/yellowbutter_Hello everyone, this is for our thesis. Do you have any idea where to buy “Collagen Degradation Assay Kit(colorimeteric)” ??? Pls help us out we need it ASAP in the Philippines submitted by /u/yellowbutter_ [link] [comments]
- by /u/MathieusstabilityMaxlfq builds pair-wise peptide ratios, on the peptides shared across samples, for a protein and the crossrun Normalization in Spectronaut, scales the Normalization factor across all samples in an experiment. What would be an ideal way to analyze, to capture patient specific response.. 1. Would analyzing all patients in one experiment still preserve patient specific response in proteome? 2. Or Would analyzing each patient between comparative conditions be ideal and provide better resolution in capturing individual response with post-hoc analysis.. ? Eg. biofluids, tissue biopsies (FF), FFPE, patient derived primary cell lines etc.. Was considering if Quant2.0 would be a […]
- by /u/Elentasubmitted by /u/Elenta [link] [comments]
- by /u/Leather_Area_2301TL;DR: My partner and I developed a new mathematical approach to predicting how proteins fold into their three-dimensional structures. To test it fairly, we ran a fully blind benchmark where our system had no access to the experimental structures during prediction. The method produced highly accurate results, with performance that was competitive with published AlphaFold CASP14 benchmark values on our test set. Unlike neural network-based approaches, our framework is deterministic, transparent, and based on exact mathematics rather than learned parameters, meaning every prediction can be independently traced, verified, and reproduced. We’ve made the code, validation data, and supporting materials completely […]
- by /u/carswellthorneHello everyone I’m interested in knowing if tears samples collection for biomarkers analysis is feasible I’m trying to include it in my research and I keep reading that biomarker detection is not that easy using schirmer strips I would appreciate if anyone has any information on the matter submitted by /u/carswellthorne [link] [comments]
- by /u/Maleficent_Slide3876submitted by /u/Maleficent_Slide3876 [link] [comments]
- by /u/Far-Acanthaceae-1623I'm working on an in-silico study involving the Mpox virus, and I have a question regarding post-translational modifications (PTMs). Specifically, do the Mpox virus proteins A35R (EEV protein) and H3L and M1R (IMV proteins) undergo post-translational modifications? If they do, are these modifications carried out by the host cell machinery, by virus-encoded enzymes, or by a combination of both? My second question is related to immunoinformatics. If an in silico vaccine or antibody is being designed against these proteins, should their PTMs be evaluated before selecting epitopes or designing antibodies? In other words, could PTMs significantly affect epitope accessibility, antigenicity, […]
- by /u/Miserable-Excuse-874Howdy y'all. Our lab recently got an Opentrons Flex and we've had it doing some cool stuff BUT we're wanting to figure out how far we can take it in a sample prep workflow. Does anybody have experience with doing STaGE tip desalting with the robot? If so, what are some tips, tricks, and recommendations you would give? Thanks in advance! submitted by /u/Miserable-Excuse-874 [link] [comments]
- by /u/Triple-TookethHas anyone tried this product: Pierce® Detergent Removal Spin Plates submitted by /u/Triple-Tooketh [link] [comments]
Mass spectrometry websites, social media, journal feeds, and other links and items of interest to the mass spectrometry community.
