- by /u/Practice100This is a personal review; Last week I purchased a MiraMist PEEK nebulizer for our Agilent ICP-MS 7700. I was experiencing back pressure issues on ignition and contacted the number on the nebulizer case. John Bergener himself called me to walk through the potential issues I was encountering. We determined it was an issue that warranted a service call, however the fact that the company’s lead took the time to reach out won my recommendation over. submitted by /u/Practice100 [link] [comments]
- by /u/Afsh31Hi y’all! Could anyone please provide information on the specific guidelines or acceptance limits for replicate testing of assay samples, if any exist? submitted by /u/Afsh31 [link] [comments]
- by /u/WesternNational4283Hello, I am a DNA chemist of 18 years and have a full analytical lab. My little brother died from what I’m suspecting is a fentanyl overdose. I found a bottle of pills to which I am going to test. It looks like LCMS is the gold standard which I have a UPLC and a single quad MS. I don’t have much small molecule experience. Obviously to identify it I’ll look for the target mass. How can I tell how much fentanyl is actually in this pill? Thank you 🙏🏾 ❤️ submitted by /u/WesternNational4283 [link] [comments]
- by /u/GreenCurrent6807We use a GC-FID to analyse many of our compounds, supplied by a hydrogen generator. We recently overhauled the H2 generator as the dessicant was wet. The dessicant is now dry, but we're having to operate at a lower pressure (35 -> 20 psi). We're seeing tailing in our GC peaks, and I was wondering if a change of hydrogen pressure to the FID could cause tailing. The carrier gas supply is unchanged. submitted by /u/GreenCurrent6807 [link] [comments]
- by /u/gimmecoffeeeIs it possible to accurately and reliably assay quantity of colloidal oatmeal in a finished product like a cream? submitted by /u/gimmecoffeee [link] [comments]
- by /u/Quirky_Reward_4822Hey all, hoping someone here has run into this before—I’m at my wit’s end. Running samples on a Waters BioAccord system, and I’ve been dealing with some persistent issues that no one, including the techs, has been able to help resolve: 1. TUV Baseline Never Returns to Zero: Even with just water (see first image), the TUV signal floats and never stabilizes around baseline. Peaks continue well after what should be the end of elution. Looks like tons of UV-active noise or carryover, but this is a water blank. 2. TUV Seems to Add a Huge Mass in MS: Whatever’s […]
- by /u/Own-Summer9796Hi. I want to know if there's anyone here who did Analytical/Quality assurance internship. I wanna apply for one but I don't know how to craft my CV. submitted by /u/Own-Summer9796 [link] [comments]
- by /u/MarketStunning6734Hey all, so we installed a new column with a liner, flame tip, and septum and started creating a new method for the compounds on GC-FID. I was almost finished with achieving decent separation on Friday and wanted to continue on Monday. When I returned, I continued running the method with the same sample, and… there was nothing anymore – no peaks except the solvent peak and some peak at the end. Has anyone experienced this issue? What could be the cause? We have tried reinstalling the column, changing the septum and ferrules, altering the temperature program and flow rate, […]
- by /u/MarketStunning6734https://preview.redd.it/e2kpo53cxtse1.png?width=1621&format=png&auto=webp&s=d7f8935a5665677cc0566e6a723368b5fa45a033 Hey all, I am currently experiencing a persistent baseline drift in my GC-FID chromatograms. The intensity of this drift is relatively low, but it is still noticeably present. We have attempted to resolve the issue by replacing the column, liner, and septum, FID flame tip but the drift persists. Given that the method we are using is somewhat aggressive, I am wondering if it could be contributing to the problem. The method, which was recommended by the column manufacturer, utilizes a rapid temperature program: Injector: 250 °C Oven: Initial temperature: 225 °C for 0.10 minutes Ramp rate: 25.0 °C/minute […]
- by /u/Infernalpain92Does anyone have a good suggestion for a cheap way to compare colors? Better would be measuring them but I’ve only a small budget. So no fancy color meters. I have a UV VIS but the samples are not transparent. Think comparing paints on a substrate. If you’re curious it’s the color of self tanner on skin. Or a skin substitute. But I don’t know how I should compare them. I thought via photographs. But it would be nicer if I could find a way to get a number to do statistics. Thx for the help!! submitted by /u/Infernalpain92 [link] […]
- by /u/Giulia5593Is KF titration suitable for water loss determination in a stability study of an injectable pharmaceutical? I know it’s routinely used to determine water content in powders but is it also suitable for acqueous solutions? submitted by /u/Giulia5593 [link] [comments]
- by /u/IndependentBass3518We are Crystal Scientific, and for the past 20 years, we have been a trusted supplier of crystals and mirrors to major synchrotrons. Additionally, over the past 5 years we have been a trusted supplier of low background silicon sample holders to Bruker and Malvern Panalytical. We are now expanding into the wider XRD powder diffraction market, offering silicon low-background discs for powder diffraction direct to users worldwide. As an in house manufacturer, we are able to produce the silicon sample holders in full and therefore can guarantee we can offer better prices than existing third part distributors, whilst offering […]
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