- by /u/Tight_Isopod6969Hi all, As the title says: What is your favorite method? I'm taking over maintenance of a 6000 series Agilent 6530 LC-qTOF MS with AJS source. In a previous life, lab chores were split and capilarly cleaning wasn't my task, and in this life the old guy left and from what I can tell hasn't cleaned the instrument in 3 years. It's an academic lab in a mid-size, mid-level university, so everything is pretty slack. Instrument runs maybe 50 samples a week of everything from biological material to aromatic polymer reaction intermediates. Sensitivity has been dropping off. I cleaned off […]
- by /u/Famous_Arugula9966Trying to remember the default password for the computer that used to operate our LCT. The account is Micromass. Anybody remember the password? submitted by /u/Famous_Arugula9966 [link] [comments]
- by /u/Next_Coconut2027We run on a Shimadzu 8060 MS, the mobile phase are Water and Methanal. The samples are plant matter above soil so flowers, stems and such. Its extracted in acidified ACN. The method has not been changed and I did make sure to check all settings. MGK-264 is run on APCI mode. Until fairly recently we didn't have any issue, it was honestly running better after switching the compound to APCI which did well for about 3 months. But recently we lost about 40-43% of the signal over the course of the total batch. The curves are good the QC […]
- by /u/ArnesianOrphansHello ! I’m new to the field and I am reading literature to enter in the world of MS. “Metastable ions” are mentioned quite a lot, what is it all about ? It seems like an important topic but I don’t get it. From what I understood a high ionization energy yields fragmentation before hitting the detector and very soft ionization yields almost only the molecular ion. With a medium ionization energy there is a population of ions getting fragmented in time and a part of the population that doesn’t, which gives a mix of both. Therefore I understand that […]
- by /u/MassSpecMenderAgilent 64XX series ESI probe, little bit beat up but still hanging on. submitted by /u/MassSpecMender [link] [comments]
- by /u/Training_Pangolin177The roughing pump is one of the two for a Sciex 6500, both start normal but one of roughing pump would quit after a short while, and bring the instrument to vent. The status light on the roughing pump started flashing green and turned solid green for a short while and then would go red and the pump quit working. Is there a tool to read the error code for the roughing pump and how to diagnosis the issue? submitted by /u/Training_Pangolin177 [link] [comments]
- by /u/Appropriate_Print124Hello, I know this might be a long shot, but I might as well try it. In my new job, we have a Waters UPLC-MSMS with waters_connect. None of us know really how to use it properly so we have been learning via trial and error and the occasional help from an apps engineer. I am trying to write the SOP for the instrument at the moment. Does anyone use the software daily and would be able to help? I want to describe the workflow from sample submit to sample process via MSQuan. I would greatly appreciate any help! Main […]
- by /u/DeepGrab4035Does anyone have experience with the iCAP MSX from Thermo? It seems to have pretty interesting features such as the IMH and peripump roller with click tensioning feature. I just don’t know how it’ll stack up to the 7850 ICP-MS as we process about 150 samples a day. submitted by /u/DeepGrab4035 [link] [comments]
- by /u/Training_Pangolin177submitted by /u/Training_Pangolin177 [link] [comments]
- by /u/Training_Pangolin177From the event log, one can only see that the instrument changed from idle to fault status and then vented. What is the right way to find out why it vented? submitted by /u/Training_Pangolin177 [link] [comments]
- by /u/Oldtimer-proteinsubmitted by /u/Oldtimer-protein [link] [comments]
- by /u/Critical_Magician_83Hi, apologies if there are rules against this question–I looked for a rules tab in this sub and did not find one but maybe I don't know what I'm doing haha. Throwaway account for reasons. I don't know anything about mass spectrometry, but it is how an acquaintance said he "tested" his items. I have some unnamed substances that I often acquire, and use fentanyl test strips every single time I acquire them for safety. This time the strips came back positive for fentanyl in my substances. My acquaintance says and showed that they've done mass spectrometry on the unnamed […]
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