Clinical Proteomics – Mass Spectrometry Blog

Journal Home

RSS

Proteomic profiles in the aqueous following anti-vegf therapy in treatment naïve neovascular age-related macular degeneration
September 1, 2025 by Anne M. Lynch, Daniel W. Drolet, Kinsey M. Trinder, Shashi Gupta, Matthew J. Westacott, Nebojsa Janjic, Alan G. Palestine, Jennifer L. Patnaik, Marc T. Mathias, Naresh Mandava and Brandie D. Wagner
Age-related macular degeneration (AMD), a degenerative disease of the photoreceptor support system of the macula, is a leading cause of vision loss in individuals over 60 years of age. In this exploratory long…
Plasma proteomics in septic shock and alcohol-related pancreatitis: a hyaluronan-centered approach
August 30, 2025 by Jaap van der Heijden, Asanda Mazubane, Marko Sallisalmi, Egor Vorontsov, Jyrki Tenhunen and Annelie Barrueta Tenhunen
Sepsis is a critical condition characterized by a dysregulated immune response to infection. As sepsis develops to septic shock, its most severe form, morbidity and mortality increases. Hyaluronan is a key com…
Urinary exosomal RAB11A serves as a novel non-invasive biomarker for diagnosis, treatment response monitoring, and prognosis in small cell lung cancer
August 25, 2025 by Weiwei Wang, Na Liu, Shanshan Wang, Chunkai Yu, Lei Pan and Man Zhang
Small cell lung cancer (SCLC) is an aggressive malignancy with a poor prognosis. This study aimed to analyze the urinary exosomal proteome of SCLC patients to identify and validate potential non-invasive bioma…
Diurnal rhythm of the human plasma proteome
August 22, 2025 by Elvar M. S. Jóhönnuson, Henriette P. Sennels, Henrik L. Jørgensen, Jens Hannibal, Ching-Yan Chloé Yeung, Christine Rasmussen, Gabriela Zofia Prus, Nicolai J. Wewer Albrechtsen and Annelaura Bach Nielsen
Plasma is the most used clinical specimen, yet diurnal variation in plasma proteins remains largely unexplored. We aimed to identify diurnally-regulated proteins in healthy individuals and assess their potenti…
Unveiling the protein landscape for early detection of colorectal precancerous lesions
August 21, 2025 by Yuanke Luo, Chong Xiao, Chuan Zheng, Simin Luo, Yifang Jiang, Fengming You, Xi Fu and Xueke Li
Colorectal cancer (CRC) has emerged as the second most prevalent cause of cancer-related mortality globally. Early identification of precancerous lesions prone to malignant transformation is pivotal in CRC pre…

Related Journals