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  • Living single-cell metabolomics via mass spectrometry: state of the art and perspective
    by Xianzhe Shi
    Chem. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D6SC00482B, Perspective Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Xianzhe Shi, Jiajun Peng, Chunxiu Hu, Muyingnan You, Xin Lu, Xinyu Liu, Guowang XuCellular heterogeneity is an inherent feature of biological systems, and living single-cell metabolomics (SCM) has emerged as a powerful approach to probe this diversity—a dimension often lost in conventional bulk…The content of this RSS Feed (c) The Royal Society of Chemistry
  • Precise construction of symmetrically coordinated triatomic zirconium catalyst for efficient oxygen reduction
    by Anaer Husile
    Chem. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D6SC01335J, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Anaer Husile, Tianmi Tang, Li-Yuan Xiao, Xue Bai, Zhenlu Wang, Jingqi GuanDeveloping an environmentally friendly, highly efficient, and stable electrocatalyst for the oxygen reduction reaction (ORR) holds critical importance for advancing the commercial viability of zinc-air batteries (ZABs). The d-band electronic…The content of this RSS Feed (c) The Royal Society of Chemistry
  • Light-regulated templated self-assembly of bilayered nanotoroids
    by Kintaro Miyamoto
    Chem. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D6SC02354A, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Kintaro Miyamoto, Sota Mihara, Hiroki Itabashi, Sougata Datta, Hiroki Hanayama, Shiki YagaiControlled molecular self-assembly driven by noncovalent interactions provides access to ordered architectures beyond the molecular scale. Yet the precise construction of higher-order assemblies remains difficult because directionality of noncovalent interactions…The content of this RSS Feed (c) The Royal Society of Chemistry
  • Acridinium amidate as a hydrogen-bonding photocatalyst for direct decarboxylative alkylation of native carboxylic acids
    by Duc An Truong
    Chem. Sci., 2026, Advance ArticleDOI: 10.1039/D6SC00657D, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Duc An Truong, Soichiro Mori, Taiki Ninomiya, Ryoya Niwa, Bumpei Maeda, Haruka Fujino, Masayuki Inoue, Kohsuke Ohmatsu, Takashi OoiThe direct generation of carbon radicals from carboxylic acids under visible-light photocatalysis offers an appealing strategy for molecular diversification.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) […]
  • The underlying synergistic mechanism of co-solvents to fabricate high-quality FAPbI3 perovskite films
    by Zezhuan Jiang
    Chem. Sci., 2026, Advance ArticleDOI: 10.1039/D6SC00647G, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Zezhuan Jiang, Xiaofeng He, Cunyun Xu, Xiaoyun Wan, Haimao Zhu, Jiancheng You, Zhongjun Dai, Wenqi Zeng, Ping Li, Jin Ye, Qunliang SongWe systematically investigate the synergistic effects of DMSO and NMP co-solvents on perovskite mesophase formation, combining theoretical and experimental insights into intermediate phase control and α-FAPbI3 crystallization.To cite this article before page numbers are assigned, use the […]
  • Electrochemically Driven Strain-Release Dearomative (3+2) Cyclization for the Synthesis of Bicyclo[2.1.1]hexane-Fused Polycyclic Spiroindolines
    by Yanren Zhu
    Chem. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D6SC01271J, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Yanren Zhu, Enfan Pu, Shaoxiong Yang, Dongbo Zhao, Qi Xu, Piaopiao Jiang, Xiong Li, Hongbin Zhang, Jingbo ChenSpiroindolines are ubiquitous structural motifs in natural products and biologically active compounds, making the development of reliable synthetic methods for their construction highly important to the synthetic chemistry community. Moreover,…The content of this RSS Feed (c) The Royal Society of Chemistry
  • Nuclear quantum effects amplify autoionization-driven superionic behaviour in nanoconfined monolayer water
    by Pavan Ravindra
    Chem. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D6SC00138F, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Pavan Ravindra, Xavier R. Advincula, Benjamin Shi, Samuel Coles, Angelos Michaelides, Venkat KapilWhile nuclear quantum effects influence autoionization in ambient-condition bulk water, their impact on autoionization-driven phase transitions is only observed at extreme conditions (in the range of many tens or hundreds…The content of this RSS Feed (c) The Royal Society of Chemistry
  • Lattice strained Na-ZnFe2O4 catalyst boosting CO2 hydrogenation to long-chain olefins
    by Xinyan Ai
    Chem. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D6SC00447D, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Xinyan Ai, Chengchao Liu, Zhe Li, Yuhua Zhang, Sixu Liu, Haifeng Xiong, Jinlin LiThermo-catalytic hydrogenation of CO2 to fuels and chemicals is an effective way for the utilization of CO2, yet it faces significant challenges due to the low CO2 conversion and product…The content of this RSS Feed (c) The Royal Society of Chemistry
  • Enhanced Crystallinity of Tetrahalopyridyl (THP) Derivatized Compounds
    by Callum Begg
    Chem. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D6SC01377E, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Callum Begg, Viktoriya Dragomanova, Dimitrii S. Yufit, Toby J Blundell, Steven L Cobb, Mark A Fox, Matthew Oliver Kitching, William D. G. BrittainPromoting the formation of ordered crystalline material is a fundamental challenge in the fields of organic synthesis, crystal engineering and wider material science. Traditional approaches typically employ strong, unidirectional intermolecular…The content of this RSS Feed (c) […]
  • Local Polarization Strategy for Efficient Sacrificial-free Hydrogen Peroxide Photoproduction
    by Donghui Wang
    Chem. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D6SC00783J, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Donghui Wang, Jin-Gang-Lu Tao, Haiyang Zhang, Po Zhang, Feng ChenPhotocatalytic production of hydrogen peroxide (H2O2) from water and oxygen under sunlight offers a safe and sustainable alternative to traditional processes. However, the sluggish water oxidation reaction (WOR) often imposes…The content of this RSS Feed (c) The Royal Society of Chemistry
  • Magnesium(0) Complexes and their Reduction Reactions with Binary Transition Metal Carbonyls
    by Yixiao Jiang
    Chem. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D6SC01992G, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Yixiao Jiang, Maryam Niksefat, Sophie G Unsworth, Joseph M Parr, Matthew J Evans, Cameron JonesThree very bulky β-diketimine protio-ligands (ArNacnacH, {(Ar)N=C(But)}2CH2, Ar = 2,4,6-tricyclohexylphenyl TCHP; 2,6-dicyclohexylphenyl DCHP; TCHP/Dip, Dip = 2,6-diisopropylphenyl) have been synthesised. These have been used to prepare monomeric, three-coordinate β-diketiminato magnesium…The content of this RSS Feed (c) The Royal Society of Chemistry
  • A Dual-Mode Large Language Model Assistant for On-Surface Reaction via Fine-Tuning and Retrieval-Augmented Generation
    by Juan Xiang
    Chem. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D6SC01168C, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Juan Xiang, Qi Huang, Xinyi Zhang, Tairan Yang, Zhiwen Zhu, Chanyu Li, Liangliang Cai, Qiang SunSurface reactions underpin catalysis, nanomaterials, energy conversion, and molecular-scale fabrication, yet the field suffers from fragmented knowledge dispersed across unstructured literature, hindering systematic analysis and data-driven discovery. Existing chemical databases…The content of this RSS Feed (c) The Royal Society of Chemistry
  • Anchoring and activation of catalytic sites on the clusters via intermolecular interactions
    by Feng Qian
    Chem. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D6SC00514D, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Feng Qian, Zhihang Zhao, Baoyu Huang, Zhixiang Xue, Qinzhen Li, Sha Yang, Jinsong Chai, Manzhou ZhuConstructing catalytically active sites on the clusters is a mainstream strategy to optimize their catalytic properties. However, it generally leads to unpredictable variations due to the notoriously sensitive relationship between…The content of this RSS Feed (c) The Royal Society of Chemistry
  • Capturing Elusive Alkenyl Radicals in Wharton Reaction and Its Interrupted Cyclization
    by Kornkamon Akkarasereenon
    Chem. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D6SC01519K, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Kornkamon Akkarasereenon, Yichen Liu, Yin Tung Lai, Rongbiao TongThe Wharton reaction is a widely used transformation in organic synthesis, enabling the conversion of α,β-epoxy ketones into versatile allylic alcohols. Despite its discovery more than 60 years ago, the…The content of this RSS Feed (c) The Royal Society of Chemistry
  • Rational Guest Selection: A General Principle for Stabilizing Multi-Component Luminescent Materials
    by Li-Ke Jing
    Chem. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D5SC09220E, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Li-Ke Jing, Yue-Yue Chang, He Li, Biao Lv, Guanyu Yang, Zhan-Ting Li, Bo YangThe practical deployment of multi-component luminescent materials is universally hampered by the photodegradation of organic guests, a fundamental challenge that conventional host-centric designs struggle to overcome. Herein, we propose a…The content of this RSS Feed (c) The Royal Society of Chemistry
  • Constructing Interconnected Gel with Ionic Fluid Channels for AC Line-Filtering
    by Jie zhang
    Chem. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D6SC02703B, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Jie zhang, Zhuanpei Wang, Xiaowei YangElectric double-layer capacitors operating at 120 Hz are promising alternatives to bulky aluminum electrolytic capacitors for AC line-filtering. However, a pivotal challenge in developing high-performance filtering electrodes is achieving the…The content of this RSS Feed (c) The Royal Society of Chemistry
  • Real-time NIR-II Fluorescence Imaging-Guided Precision Thrombolysis with a Molecularly Planarized Phototheranostic Agent
    by Guosheng Zhang
    Chem. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D6SC00914J, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Guosheng Zhang, Leilei Si, Fuhai Zhou, Xiaofang Song, Hongming WangThe precise diagnosis and treatment of intravascular thrombosis pose a major clinical challenge, as existing technologies struggle to simultaneously achieve high-resolution imaging and highly efficient yet safe therapy. To address…The content of this RSS Feed (c) The Royal Society of Chemistry
  • Xanthene-to-fluorene skeletal editing via oxygen deletion mediated by boron and aluminium radicals
    by Emily Nahon
    Chem. Sci., 2026, Advance ArticleDOI: 10.1039/D6SC01056C, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Emily Nahon, Gareth R. Nelmes, Elena Dallerba, Li Feng Lim, Nicholas Cox, Claire L. McMullin, Massimiliano Massi, Fabian Kallmeier, Jamie HicksTaking oxygen-free chemistry to the next level: the O-deletion reaction of diamidoarylether ligands coordinated to boron or aluminium is presented, affording 4,5-diaminofluorene compounds on a gram scale.To cite this article before page numbers are assigned, use the DOI […]
  • Charge-regulated hepatic γ-glutamyltranspeptidase fluorescent probe: in vivo staging Schistosoma-infection
    by Xiaoxi Ma
    Chem. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D6SC02037B, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Xiaoxi Ma, Eryang Xie, Qiang Li, Chuyang Sun, Yongkang Yao, Chenxu Yan, Qianfu Luo, Zhiqian Guo, Weihong ZhuSchistosomiasis remains a formidable global health threat, yet current diagnostic modalities like microscopy and ultrasonography suffer from limited sensitivity and critical inability for real-time in vivo monitoring, posing significant hurdles…The content of this RSS Feed (c) The Royal Society of Chemistry
  • Molecular-level precursor engineering enables high utilization of closed nanopores in hard carbon for sodium-ion batteries
    by Rui Li
    Chem. Sci., 2026, Advance ArticleDOI: 10.1039/D6SC01648K, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Rui Li, Beilei Yuan, Yupeng Feng, Yuhan Li, Na Jiang, Ping Liu, Liangzhi Li, Weiyue Li, Chunwei Dong, Shuchun Hu, Qi Liu, Jian Chen, Fei Li, Jianping Long, Anjun HuThis work proposed a molecular-templating carbonization strategy achieves 86% closed-pore utilization of bamboo-carbon and improves sodium storage capacity via pore regulation.To cite this article before page numbers are assigned, […]

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