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  • When Fluorination Becomes Inactive: Solvation Exclusion and Interfacial Kinetics in Ni-Rich Lithium-Ion Batteries
    by Thanitsavat Sirirat
    Chem. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D6SC03512D, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Thanitsavat Sirirat, Sukritta Janprakhon, Nattanon Joraleechanchai, Surat Prempluem, Salatan Duangdangchote, Montree SawangphrukFluorinated carbonate additives are widely employed to stabilize electrolytes for high-energy lithium-ion batteries (LIBs), yet the interplay between fluorination degree, molecular geometry, and lithium-ion (Li⁺) solvation remains poorly understood. It…The content of this RSS Feed (c) The Royal Society of Chemistry
  • Membrane Anchoring Amplifies Intracellular Catalysis of Caged Palladium Nanoclusters
    by Zhengnuo Ba
    Chem. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D6SC02576E, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Zhengnuo Ba, Jiadong Tang, Junji Zhang, Chen WangPalladium nanoclusters (Pd NCs) represent a promising candidate for intracellular redox catalysis owing to their capacity to generate reactive oxygen species (ROS). Yet, in living systems, their catalytic performance is…The content of this RSS Feed (c) The Royal Society of Chemistry
  • GFP Chromophore Photophysics: Ultrafast Dynamics and Hot Ground State Cooling in the Neutral Form
    by Anam Fatima
    Chem. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D6SC02114J, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Anam Fatima, Mark H Stockett, Eleanor K Ashworth, Woojin Park, Cheol Choi, Joseph A Wright, Pratip Chakraborty, Partha Malakar, Steve R. Meech, James N BullThe neutral GFP chromophore is the photoactive form in many photoconvertible and photoswitchable fluorescent proteins, yet experimental characterisation of its ultrafast dynamics requires clear assignment of the associated transient signals….The content of this RSS […]
  • Alternating copolymerization of L-lactide and ε-caprolactone via enantiomorphic site and chain-end synergistic control
    by Ji Xian
    Chem. Sci., 2026, Advance ArticleDOI: 10.1039/D6SC04630D, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Ji Xian, Guojie Li, Linyun Wu, Hongjun Fu, Chunmei Wang, Shaoyu Lü, Xiaobo Pan, Jincai WuHighly alternating copolymerization of L-lactide and ε-caprolactone is achieved via an enantiomorphic site and chain-end synergistic control strategy. This strategy yields sequence-controlled polyesters with exceptional regularity (Palt > 0.90).To cite this article before page numbers are assigned, use the DOI form of citation […]
  • Correction: Conditional generation of free radicals by selective activation of alkoxyamines: towards more effective and less toxic targeting of brain tumors
    by Patricia Piris
    Chem. Sci., 2026, Advance ArticleDOI: 10.1039/D6SC90135B, Correction Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Patricia Piris, Duje Buric, Toshihide Yamasaki, Paul Huchedé, Maïlys Rossi, Mélanie Matteudi, Marie-Pierre Montero, Anne Rodallec, Romain Appay, Christine Roux, Sébastien Combes, Eddy Pasquier, Marie Castets, Nicolas André, Paul Brémond, Manon CarréTo cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry
  • Stabilizing sub-nanoporous zinc metal–organic frameworks in SnTe thermoelectrics for high-temperature power generation
    by Wang Yue
    Chem. Sci., 2026, Advance ArticleDOI: 10.1039/D6SC04137J, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Wang Yue, Decheng An, Jiali Ren, Fangyuan Chen, Zhijun Hao, Jiaxi Song, Zejin Li, Wutao Yang, Shaoping Chen, Yuan Yu, Xian-Ming ZhangThe integration of porous metal–organic frameworks (MOFs) with thermoelectric materials offers an effective route toward the phonon-glass electron crystal paradigm.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of […]
  • Substituent Engineering of Dynamic Covalent Bonds Enables Simultaneous Enhancement of Performance and Recyclability
    by Zhiyong Liu
    Chem. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D6SC04529D, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Zhiyong Liu, Qian Chao, Jinyan Zhao, Ying Lin, Ping Yu, Min Chen, Shengyu Shi, Yixin Xiang, Jiangang Gao, Youwei MaA central challenge in designing recyclable polymers lies in the trade-off between recyclability and performance. State-of-the-art strategies leveraging supramolecular interactions or dynamic covalent bonds (DCBs), either individually or in orthogonal…The content of this RSS Feed (c) The Royal Society […]
  • Engineering Asymmetric Solvation Structures for Synergistically Boosted Quasi-Solid Thermocells
    by Wentao Lin
    Chem. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D6SC03942A, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Wentao Lin, Shuo Niu, Shukai Wu, Chao FangQuasi solid-state thermocells (QTECs) based on the thermogalvanic effect offer a promising route for directly converting abundant low-grade heat into electricity. Introducing a single solvent into hydrogel electrolytes, a common…The content of this RSS Feed (c) The Royal Society of Chemistry
  • Materials Process Informatics-Assisted Precise Particle Size Control of Metal-Organic Framework
    by ＹＵＡＮ ＷＡＮＧ
    Chem. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D6SC03212E, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.ＹＵＡＮ ＷＡＮＧ, Heng Liu, Yusuke Hashimoto, Kazuyuki Iwase, Hao Li, Takaaki TomaiPrecise control over the particle size of metal–organic frameworks (MOFs) is pivotal for optimizing their performance in catalysis, separation, and drug delivery. However, conventional synthetic strategies largely depend on empirical…The content of this RSS Feed (c) The Royal Society of Chemistry
  • Recent Progress in Catalytic Asymmetric Synthesis of Triarylmethanes
    by Han Yajing
    Chem. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D6SC02570F, Review Article Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Han Yajing, Luyao Li, Teck Peng LohChiral triarylmethanes, with their unique three-dimensional spatial configuration, tunable electronic properties, and excellent functional group compatibility, have wide applications in fields such as the dye industry, materials science, and medicinal…The content of this RSS Feed (c) The Royal Society of Chemistry
  • Improving the accuracy and generalizability of molecular property regression models with a substructure-substitution-rule-informed framework
    by Xiaoyu Fan
    Chem. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D6SC01813K, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Xiaoyu Fan, Lin Guo, Ruizhen Jia, Yang Tian, Zhihao Yang, Weihao Li, Boxue TianAbstract Artificial Intelligence (AI)-aided drug discovery is an active research field, yet AI models often exhibit poor accuracy in regression tasks for molecular property prediction, and perform catastrophically poorly for…The content of this RSS Feed (c) The Royal Society of Chemistry
  • A spatially confined “double-key lock” smart DNA hydrogel for dynamic detection of MicroRNA in cells
    by Liyun Shi
    Chem. Sci., 2026, Advance ArticleDOI: 10.1039/D6SC03610D, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Liyun Shi, Dandan Liang, Jingyu Kuang, Yuting He, Dongyang Wang, Jiayi Shan, Ziyang Wang, Wei Shen, Hian Kee Lee, Sheng TangA spatially confined “double-key lock” smart DNA hydrogel integrating temperature responsiveness and target recognition was developed to realize dynamic monitoring of miRNA in cells.To cite this article before page numbers are assigned, use the DOI form of citation […]
  • Correction: Sterically controlled 5-exo-dig cyclization enables synthesis of non-benzenoid polycyclic aromatic hydrocarbons with intriguing (anti)aromaticity and diradical properties
    by Liangliang Chen
    Chem. Sci., 2026, Advance ArticleDOI: 10.1039/D6SC90125E, Correction Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Liangliang Chen, Zhichun Shangguan, Tianyu Shi, Liyuan Qin, Yiyun Zeng, Qingqiu Zhu, Jin Chen, Junhong Liang, Wentao Miao, Yurong He, Xiaosong Qiu, Xunchang Wang, Deqing Zhang, Renqiang YangTo cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry
  • Concise Synthesis of Simplified Aogacillin Analogs Reveals Innate Reactivity and Synergy with Aminoglycosides
    by Andrew R. LeBlanc
    Chem. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D6SC04046B, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Andrew R. LeBlanc, Jacqueline R. Smith, Audrey J. Isakov, John Bacsa, William WuestAogacillins (AOGs) A-B, two diastereomeric natural products isolated from Simplicillium sp. FKI-5985, were reported to have potent synergism with aminoglycoside antibiotics. Herein, we show that structural simplification expedites the synthesis…The content of this RSS Feed (c) The Royal Society of Chemistry
  • Chiral recognition of 2,3-dihydroxypropanesulfonate by bacterial transport proteins adapted to distinct ecological niches
    by Helen Barber
    Chem. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D6SC02372J, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Helen Barber, Sabrina Borusak, Adam William Endian Stewart, Hamza Tahir, Nichollas Scott, David Shleheck, Mihwa Lee, Spencer J Williams2,3-Dihydroxypropanesulfonate (DHPS) is an abundant organosulfonate that links sulfosugar catabolism to sulfur mineralization in marine and gut environments. In surface seawater, DHPS occurs as a dilute, mixed R/S pool, whereas…The content of this RSS Feed (c) The Royal Society of […]
  • De novo design of NIR-II thioxanthene dye and phosphate-driven charge transfer-coupled J-aggregates for high resolution tumor angiography and type I phototherapy against hypoxic tumors
    by Chuangli Zhang
    Chem. Sci., 2026, Advance ArticleDOI: 10.1039/D6SC01958G, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Chuangli Zhang, Ziyong Wu, Yang Bai, Jing He, Mengyuan Miao, Feiyu Diao, Qingzhi Wang, Shan Zhong, Pengfei Shi, Xin-Yue Song, Shusheng ZhangA NIR-II thioxanthene-based dye was designed by replacing O with S. Driven by phosphates, JCT-aggregates were constructed. The JCT-aggregates achieved high-resolution NIR-II FL/PA tumor angiography and efficient type I phototherapy of hypoxic tumors.To cite this article before […]
  • Strong Interactions between Carbones and Halogen Atomic Centers
    by Shunhua Li
    Chem. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D6SC02210C, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Shunhua Li, Hangyu Zhou, Qingzhong Li, Steve ScheinerCarbone compounds are characterized by a zero oxidation state on divalent C, which contains two lone, coupled with dative bonding to its two substituents. The ability of this carbone center…The content of this RSS Feed (c) The Royal Society of Chemistry
  • Interaction–structure coupling enables high-flux enantioselective transport in lamellar membranes
    by Siqi Han
    Chem. Sci., 2026, Advance ArticleDOI: 10.1039/D6SC03058K, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Siqi Han, Furong Yuan, Honghong Cao, Wentao Han, Ximeng Chen, Hongyan Wan, Zhan LiInteraction–structure coupling in rGO–ssDNA–SWCNT lamellar membranes amplifies weak chiral recognition into gallery reconfiguration and transport-barrier differences, enabling fast L-Phe permeation with high enantioselectivity.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The […]
  • Amide α-C-H Oxidative Coupling Reactions Enabled by Base-Promoted Halogen Transfer
    by Faith E. Kidd
    Chem. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D6SC02461K, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Faith E. Kidd, Cristian Vásquez Tapia Vera, Jeffrey S. BandarA base-promoted protocol for the direct oxidative coupling of amide α-C-H bonds with common O-, S-, and N-pronucleophiles is described. This process operates via a synergistic deprotonation, halogenation, and substitution…The content of this RSS Feed (c) The Royal Society of Chemistry
  • Ga-Induced Electron Pump Optimization of Fe active sites in NiFe-LDHs for Efficient Alkaline Water Electrooxidation
    by Yu Shuai
    Chem. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D6SC00682E, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Yu Shuai, Shucheng Liu, Gangbiao Li, Yi LiuThe development of efficient and stable electrocatalysts for the alkaline oxygen evolution reaction (OER) is crucial for large-scale industrial application in producing green hydrogen. Herein, we propose a targeted electronic…The content of this RSS Feed (c) The Royal Society of Chemistry

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