- by MS ArticlesAnalytical ChemistryDOI: 10.1021/acs.analchem.4c05789
- by MS ArticlesABSTRACT Cembranoids are significant flavor precursors found in flue-cured tobacco leaves. The degradation products can serve as important aromatic compounds. In this study, 16 cembranoids were discovered in flue-cured tobacco leaves by liquid chromatography–mass spectrometry (MS), and 1 cembranoid featuring both oxidation and dehydrogenation from α/β-cembranoid was identified for the first time. α- and β-cembranoids were confirmed to be precursors […]
- by MS ArticlesPublication date: Available online 21 February 2025Source: Journal of Mass Spectrometry and Advances in the Clinical LabAuthor(s): Difei Sun, Donna Sealy, Dorothy Truong, Danijela Konforte
- by MS ArticlesPublication date: Available online 21 February 2025Source: Journal of Chromatography BAuthor(s): Sangeun Lee, Jihyun Lee, Dain Jang, Hee-jung Cho, Seonmi Choi, Eunbin Ryu, Wonhee Koo, Jaewoo Song, Jea-sung Pyo, Na Young Lim, Chan Hyeok Kwon, Kikyung Jung, Jin Young Kim, Sungill Suh, Youngmin Hong, Eunyoung Han
- by MS ArticlesPublication date: Available online 22 February 2025Source: Journal of ProteomicsAuthor(s): Masaaki Sato, Kouhei Nagai, Toshiyuki Sato, Ryo Yoshimoto, Yuto Shibano, Minori Shibahara, Haruka Satokawa, Masayuki Anzai, Teisuke Uchida, Atsuhiro Tsutiya, Yukiko Takakuwa, Kazuki Omoteyama, Mitsumi Arito, Naoya Suematsu, Seido Ooka, Kimito Kawahata, Tomohiro Kato, Manae S. Kurokawa
- by MS ArticlesABSTRACT Mume Fructus (MF), a representative substance in the field of medicine-food homology, has been extensively utilized in clinical treatments and daily diets for its raw and processed forms. This study aimed to establish the spectrum-effect relationship between ultra–high-performance liquid chromatography coupled with quadrupole tandem time-of-flight mass spectrometry (UHPLC-Q-TOF-MS/MS) fingerprints and anti-inflammatory and antitussive activities of raw and processed MF […]
- by MS ArticlesPROTEOMICS, EarlyView.
- by MS ArticlesAbstract The spatial metabolic analysis of tumor tissues following neoadjuvant chemotherapy (NAC) is critical for understanding chemotherapy-induced metabolic changes. Matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI MSI) offers a powerful tool for revealing spatially resolved metabolic profiles within tissues. However, necrotic regions in post-NAC tissues are fragile, creating challenges for sample preparation and MALDI MSI analysis. In this study, we […]
- by MS ArticlesAnalytical ChemistryDOI: 10.1021/acs.analchem.4c05961
- by MS ArticlesPublication date: Available online 21 February 2025Source: Analytica Chimica ActaAuthor(s): Anpu Wang, Taghi Sahraeian, Abraham K. Badu-Tawiah, Susan V. Olesik
- by MS ArticlesPublication date: Available online 20 February 2025Source: Journal of Chromatography BAuthor(s): Haihong Jia, Ruihong Li, Yahui Li, Fen Lu, Lan Ma, Xiujuan Xu
- by MS ArticlesAs part of the US HUPO sponsored "Philly Express" series highlighting speakers at the upcoming 2025 US HUPO meeting in Philadelphia, Ben and Ben sit down to talk with Dr. Jesse Meyer, Cedars Sinai Medical Center, winner of the 2025 Robert J. Cotter New Investigator Award.
- by MS ArticlesTHIS is the study that I've been waiting for. I don't know how it wasn't blowing up the interwebs when it dropped, but here it is.
- by MS ArticlesJournal of the American Society for Mass SpectrometryDOI: 10.1021/jasms.4c00448
- by MS ArticlesAnalytical ChemistryDOI: 10.1021/acs.analchem.4c04516
- by MS ArticlesJournal of Mass Spectrometry, Volume 60, Issue 3, March 2025.
- by MS ArticlesABSTRACT Metabolomics, a powerful discipline within systems biology, aims at comprehensive profiling of small molecules in biological samples. The challenges of biological sample complexity are addressed through innovative sample preparation methods, including solid-phase extraction and microextraction techniques, enhancing the detection and quantification of low-abundance metabolites. Advances in chromatographic separation, particularly liquid chromatography (LC) and gas chromatography (GC), coupled with high-resolution […]
- by MS ArticlesABSTRACT The widespread use of organophosphorus pesticides (OPs) has raised significant environmental and health concerns due to their residues in soil and potential entry into the food chain. This study introduced chiral analysis methods for four OPs—methamidophos (METHP), dipterex (DIP), malathion (MALA), and isothiophos-methyl (ISOME)—using liquid chromatography–tandem mass spectrometry (LC–MS/MS) with cellulose-based chiral columns. Three distinct methods were established: one […]
- by MS ArticlesPublication date: Available online 19 February 2025Source: Analytica Chimica ActaAuthor(s): Lorenzo Toma, Maurizio Piergiovanni, Silvia Gentili, Monica Mattarozzi, Maria Careri, Encarnación Moyano
- by MS ArticlesPublication date: Available online 19 February 2025Source: Analytica Chimica ActaAuthor(s): Ids B. Lemmink, Sipke Bosma, Toine F.H. Bovee, Han Zuilhof, Gert IJ. Salentijn