Murray Mass Spectrometry Group
Research group of Kermit Murray at Louisiana State University where we use lasers for sampling and imaging and study the chemistry and physics of laser ablation.
K. K. Murray, , C. A. Seneviratne, and S. Ghorai, “High Resolution Laser Mass Spectrometry Bioimaging” Methods 104 (2016) 118–126; doi:10.1016/j.ymeth.2016.03.002 Mass spectrometry imaging (MSI) was introduced more than five decades ago with secondary ion mass spectrometry (SIMS) and a decade later with laser desorption/ionization (LDI) mass spectrometry (MS). Large biomolecule imaging by matrix-assisted laser …
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Murray, K. K. “The Term ‘Multiple Reaction Monitoring’ Is Recommended.” Rapid Commun. Mass Spectrom. 2015, 29, 1926–1928. DOI: 10.1002/rcm.7297
F. Donnarumma, F. Cao, & K. K. Murray, J. Am. Soc. Mass Spectrom. (2015) DOI: 10.1007/s13361-015-1249-0 We have developed a laser ablation sampling technique for matrix-assisted laser desorption ionization (MALDI) mass spectrometry and tandem mass spectrometry (MS/MS) analyses of in-situ digested tissue proteins. Infrared laser ablation was used to remove biomolecules from tissue sections for …
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C. A. Seneviratne, S. Ghorai & K. K. Murray, Rapid Commun. Mass Spectrom. in press DOI: 10.1002/rcm.7419 RATIONALE: Ambient mass spectrometry can detect small molecules directly, but complex mixtures can be a challenge. We have developed a method that incorporates small molecule separation based on laser desorption with 80 capture on a solid-phase microextraction (SPME) …
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Al Ghafly, Siraj, Das, Regmi, Magut, Galpothdeniya, Murray, Warner, Rapid Commun. Mass Spectrom. 2014, 28, 2307; DOI: 10.1002/rcm.7027. RATIONALE Detection of hydrophobic peptides remains a major obstacle for matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS). This stems from the fact that most matrices for MALDI are hydrophilic and therefore have low affinities for hydrophobic peptides. Herein, …
