Ultra sensitive affinity chromatography on avidin-functionalized PMMA microchip for low abundant post-translational modified protein enrichment

H. Xia, K. Murray, S. Soper, J. Feng, Ultra sensitive affinity chromatography on avidin-functionalized PMMA microchip for low abundant post-translational modified protein enrichment, Biomed. Microdevices, 14 (2012) 67-81; doi: 10.1007/s10544-011-9586-7 Abstract Post-translational modifications (PTM) of proteins play essential roles in cellular physiology and disease. The identification of protein substrates and detection of modification site helps …