Mass spectrometry RSS feeds from journals and social media.
- by MS ArticlesPublication date: Available online 1 April 2025Source: Journal of ProteomicsAuthor(s): Dandan Zhang, Hairong Zhang, Yuexin Yang, Ying Jin, Yingjie Chen, Caisheng Wu
- by MS ArticlesJournal of the American Society for Mass SpectrometryDOI: 10.1021/jasms.4c00465
- by MS ArticlesJournal of the American Society for Mass SpectrometryDOI: 10.1021/jasms.5c00012
- by MS ArticlesPublication date: Available online 1 April 2025Source: International Journal of Mass SpectrometryAuthor(s): Sudam S. Mane, Easton K. Cox, Cole D. Warner, David V. Dearden, Kenneth W. Lee
- by MS ArticlesAnalytical ChemistryDOI: 10.1021/acs.analchem.4c05228
- by MS ArticlesPublication date: Available online 1 April 2025Source: Analytica Chimica ActaAuthor(s): Guoliang Huang, Baoshan Zang, Yunna Li, Guohua Zhu, Kezhi Jiang
- by MS ArticlesPublication date: Available online 1 April 2025Source: Analytica Chimica ActaAuthor(s): Jianglong Du, Shutong Yang, Yanqiu Chu, Yinghua Yan, Zhenhua Li, Chuan-Fan Ding
- by MS ArticlesPublication date: Available online 1 April 2025Source: Analytica Chimica ActaAuthor(s): Gaosheng Zhao, Yuliang Huang, Bin Jia, Jiafan Ji, Ping Cheng
- by MS ArticlesThis is a solid new resource for figuring out if your search engine is lying to you about those modified peptides. Case study? That miserable region of histones where everything is conserved and everything can have multiple PTMs and – worst of all -people really truly care about which PTM is where!
- by MS ArticlesSometimes you need a very large sequence database, e.g. search all proteobacteria proteins. Mascot Server has no size limit. Search a database of hundreds of millions of protein sequences without running out of resources.https://www.matrixscience.com/blog/big-databases-and-large-peak-lists.html#proteomics #MassSpec
- by MS ArticlesChemistry – A European Journal, Volume 31, Issue 19, April 1, 2025.
- by MS ArticlesABSTRACT Background Atmospheric particulate matter (PM) is a complex mixture with a wide range of sources, but only a limited proportion can be identified by existing analytical techniques. Comprehensive two-dimensional gas chromatography–mass spectrometry (GC × GC-MS) couples the advantages on high resolution, sensitivity, and peak capacity on gas chromatography, together with the high mass accuracy and acquisition frequency of time-of-flight mass spectrometry (TOFMS). GC × GC-MS has been gradually applied on the analysis of environmental organic pollutants. Aims This review introduces the principles of […]
- by MS ArticlesWe have previously demonstrated that the transcription-dependent interaction of the promoter and terminator ends of a gene, which results in the formation of a gene loop, is facilitated by the interaction of the general transcription factor TFIIB with the CF1, CPF and Rat1 termination complexes. To further elucidate the protein-protein interactions that stabilize gene loop, we performed mass spectrometry of affinity purified termination complexes from chromatin fraction. Quantitative proteomic analysis revealed additional interactions of termination factors with TFIID and SAGA […]
- by MS ArticlesInterferon-induced antiviral proteins act on the first line of defence against viruses, including influenza A virus (IAV). Among those, the short isoform of Nuclear Receptor Coactivator 7 (NCOA7-AS) has been shown to inhibit IAV entry and more especially the fusion between endosomal and viral membranes. Ectopic expression of NCOA7-AS leads to the increased acidification of the endolysosomal pathway, putatively through NCOA7-AS interaction with the vacuolar ATPase (V-ATPase). However, the precise mechanism of action of NCOA7-AS is not fully understood. Here, […]
- by MS ArticlesRationale: Epilepsy presents significant sex-based disparities in prevalence and manifestation. Epidemiological studies reveal that epilepsy is more prevalent in males, with lesional types being more common, whereas idiopathic generalized epilepsies are more frequently observed in females. These differences stress the importance of considering sex-specific factors in epilepsy diagnosis, treatment, and mechanistic research using preclinical models. To elucidate potential molecular differences that could explain these disparities and inform personalized treatment strategies, we conducted a proteomic analysis of epileptic brain tissues from […]
- by MS ArticlesJournal of Proteome ResearchDOI: 10.1021/acs.jproteome.4c00742
- by MS ArticlesProtein complexes are essential for virtually all biological processes, yet their structural characterization remains a major challenge due to their heterogeneous, dynamic nature and the complexity of the proteome. Native top-down mass spectrometry (nTDMS) has emerged as a powerful tool for comprehensive structural characterization of purified protein complexes, but its application to endogenous protein complexes in the proteome is challenging and typically requires labor-intensive and time-consuming prefractionation. Here, for the first time, we develop a nondenaturing online two-dimensional liquid chromatography […]
- by MS ArticlesJournal of the American Society for Mass SpectrometryDOI: 10.1021/jasms.4c00474
- by MS ArticlesBackground: While operative and perioperative care continues to improve for single ventricle congenital heart disease (SV), long-term morbidities and mortality remain high. Importantly, phosphodiesterase-5 inhibitor therapies (PDE5i) are increasingly used, however, little is known regarding the direct myocardial effects of PDE5i therapy in the SV population. Objectives: Our group has previously demonstrated that the failing SV myocardium is characterized by increased PDE5 activity and impaired mitochondrial bioenergetics. Here we sought to determine whether serum circulating factors contribute to pathological metabolic […]
- by MS ArticlesAnalytical ChemistryDOI: 10.1021/acs.analchem.4c06949
- by MS ArticlesAnalytical ChemistryDOI: 10.1021/acs.analchem.5c00386
- by MS ArticlesAnalytical ChemistryDOI: 10.1021/acs.analchem.5c00429
- by MS ArticlesJournal of Mass Spectrometry, Volume 60, Issue 4, April 2025.
- by MS ArticlesAge-related vascular changes accompany or precede the development of Alzheimer's disease (AD) pathology. The comorbidity of AD and arterial stiffening may suggest that vascular changes have a pathogenic role. Carotid artery mechanics and hemodynamics have been associated with age-related cognitive decline. However, the impact of hemodynamics and vascular mechanics on regional vulnerability within the brain have not been thoroughly explored. Despite the venous system's role in transport, the impact of age-related alterations of the brain venous circulation on cognitive impairment […]
- by MS ArticlesFor an old post on what a Lab Developed Test (LDT) is vs an In Vitro Diagnostic (IVD) you can go here. And…in what was an altogether extremely bad day for the FDA with thousands of people finding out when they tried to use their badges and they simply didn't work – they also lost a federal appeal in this recent ruling.The American Clinical Lab Association sued to overturn FDA's new rules for moving all new (?) or all (?) diagnostics […]