- by MS ArticlesPublication date: Available online 8 January 2026Source: International Journal of Mass SpectrometryAuthor(s): Zhe Fang, Lei Wang, Kai Li, Chaogang Wang, Lizhi Ren, Yaqiang Li, Yihui Wang, Ming Chen, Haizhou Wang
- by MS ArticlesPublication date: Available online 8 January 2026Source: International Journal of Mass SpectrometryAuthor(s): Lasini Amunugama, Jared B. Shaw
- by MS ArticlesWe investigated how seed proteolysis was enhanced by germination, by subsequent homogenisation (disrupting sprout compartments), and by co-incubation of homogenates from different species. Mass spectrometry of released peptides tracked proteolytic signatures from chickpea, lentil, mung and broccoli proteins, in soaked seeds, in sprouted seeds, and after sprout homogenisation followed by incubation alone or in mixture with other sprouts. The proteolytic […]
- by MS ArticlesJ. Anal. At. Spectrom., 2026, Accepted ManuscriptDOI: 10.1039/D5JA00337G, Technical NoteLouise Darricau, Jérôme Aléon, Maximilien Verdier, Virginie Sellier, Josselin Gorny, Smail Mostefaoui, Cyrielle Jardin, Arnaud Mangeret, Arnaud Duverger, Nicolas Ait-Ouabbas, David Suhard, Gilles Montavon, Alkiviadis GourgiotisThis study presents an analytical protocol for the quantitative imaging of 226Ra by Nanoscale Secondary Ion Mass Spectrometry (NanoSIMS), based on the synthesis and characterization of […]
- by MS ArticlesPublication date: 15 May 2026Source: Talanta, Volume 302Author(s): Annika Haase, Gertrud Morlock
- by MS ArticlesPublication date: Available online 8 January 2026Source: TalantaAuthor(s): Xiaoyu Wei, Xudong Wang, Ming Xu
- by MS ArticlesJournal of the American Society for Mass SpectrometryDOI: 10.1021/jasms.5c00340
- by MS ArticlesJournal of the American Society for Mass SpectrometryDOI: 10.1021/jasms.5c00276
- by MS ArticlesAnalytical ChemistryDOI: 10.1021/acs.analchem.5c06533
- by MS ArticlesABSTRACT The objective was to achieve accurate origins discriminations of flos of Lonicerae japonicae, especially those from the genuine and non-genuine producing areas. An integration strategy was proposed based on machine learning, combining ultra-high performance liquid chromatography-time-of-flight mass spectrometry and gas chromatography-ion mobility chromatography data fusion for geographical origins discrimination of flos of Lonicerae japonicae. Sixty-one batches of flos of […]
- by MS ArticlesHuman myoglobin (hMYO) is a sensitive early biomarker for acute myocardial infarction, rising within 1~3 h after myocardial injury and offering high predictive value for excluding infarction. To standardize its measurement, a precise quantitative method combining magnetic bead extraction with liquid chromatography–isotope dilution tandem mass spectrometry (LC‑IDMS/MS) was established. 15NLabeled myoglobin was spiked into serum as an internal standard, and magnetic […]
- by MS ArticlesProteomics software is prone to filling up the disk with data and temp files, which can cause weird issues. This blog article lists the most common errors in Mascot products and how to free up disk space.https://www.matrixscience.com/blog/strange-software-failures-check-your-disk-space.html#proteomics #massspec
- by MS ArticlesTo survive stressful conditions, bacteria enter the stringent response mediated by the magic spot nucleotides (MSN) guanosine 3', 5' bispyrophosphate (ppGpp) and guanosine 3'-diphosphate 5' triphosphate (pppGpp). Another group of so-called alarmones elevated under stress are dinucleoside polyphosphates (NpnNs), such as diadenosine triphosphate (Ap3A). How these two groups of alarmones intersect with one another is poorly understood. Here, we present […]
- by MS ArticlesAs part of the US HUPO sponsored "Pony Express" series highlighting speakers at the upcoming 2026 US HUPO meeting in St. Louis, Ben and Ben sit down to talk with Dr. Jeffrey Gordon, Washington University, who will be giving the opening plenary.keywords: microbiome; human gut; #24; philosophy of science
- by MS ArticlesThe photoprotective efficacy of natural skin-active complexes is well recognized, yet their application is often hindered by the challenge of deciphering their complex, multi-component, and multi-target mechanisms. To bridge the gap between established phenotypes and molecular mechanisms, we developed an AI-driven integrated platform that combines phytochemical profiling, network pharmacology, and deep learning-based target prediction with rigorous biophysical validation. We applied […]
- by MS ArticlesImmunoglobulin light chains, a component of antibodies, can misfold and aggregate to cause systemic AL amyloidosis. Aggregation, including amyloid fibril formation, requires unfolding of the full-length light chain from its native state, and in most cases aberrant proteolysis. Small molecules that bind to the native state of light chains to stabilize them against conformational excursions and proteolysis are under development […]
- by MS ArticlesPublication date: 1 May 2026Source: Talanta, Volume 301Author(s): Lucas Abruzzi, Jack Gillies, Erik T. Krogh, Daniel G. Beach, Chris G. Gill
- by MS ArticlesAnal. Methods, 2026, Accepted ManuscriptDOI: 10.1039/D5AY01566A, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Cécile Dionne Edoa, Ken Goeury, Justine Fontaine, Sébastien SauvéA sensitive method has been developed for the analysis of the three subclasses of dithiocarbamates (DTCs), (dimethyl dithiocarbamates (DMDs), ethylenebisdithiocarbamates (EBDs), propylenebisdithiocarbamates (PBD)) in berries and leafy vegetables using UHPLC/MS-MS….The content […]
- by MS ArticlesChemical proteomics is a powerful method to track proteins labelled by reactive small molecules in living cells on proteome-wide scale. The strategy relies on reactivity and specificity of bioorthogonal click reactions. Although a variety of bioorthogonal reactions have been developed to facilitate chemical proteomics, their reactivity and specificity might not be comparable with enzymatic reactions. Here we describe an iodoacetamide […]
- by MS ArticlesProtein secretion is a fundamental mechanism for cellular coordination and signalling, with its dysregulation leading to widespread physiological dysfunction and disease. Immunoassay formats that utilise secondary antibody readouts are the current gold standard for measuring secreted proteins, offering high specificity and sensitivity, but relying on predefined protein panels that constrain the discovery of novel biology. We present a scalable mass […]
Murray Mass Spectrometry Group
Research group of Kermit Murray at Louisiana State University where we use lasers for sampling and imaging and study the chemistry and physics of laser ablation.
