- by MS ArticlesPublication date: Available online 1 April 2025Source: Journal of ProteomicsAuthor(s): Dandan Zhang, Hairong Zhang, Yuexin Yang, Ying Jin, Yingjie Chen, Caisheng Wu
- by MS ArticlesJournal of the American Society for Mass SpectrometryDOI: 10.1021/jasms.4c00465
- by MS ArticlesJournal of the American Society for Mass SpectrometryDOI: 10.1021/jasms.5c00012
- by MS ArticlesPublication date: Available online 1 April 2025Source: International Journal of Mass SpectrometryAuthor(s): Sudam S. Mane, Easton K. Cox, Cole D. Warner, David V. Dearden, Kenneth W. Lee
- by MS ArticlesAnalytical ChemistryDOI: 10.1021/acs.analchem.4c05228
- by MS ArticlesPublication date: Available online 1 April 2025Source: Analytica Chimica ActaAuthor(s): Guoliang Huang, Baoshan Zang, Yunna Li, Guohua Zhu, Kezhi Jiang
- by MS ArticlesPublication date: Available online 1 April 2025Source: Analytica Chimica ActaAuthor(s): Jianglong Du, Shutong Yang, Yanqiu Chu, Yinghua Yan, Zhenhua Li, Chuan-Fan Ding
- by MS ArticlesPublication date: Available online 1 April 2025Source: Analytica Chimica ActaAuthor(s): Gaosheng Zhao, Yuliang Huang, Bin Jia, Jiafan Ji, Ping Cheng
- by MS ArticlesThis is a solid new resource for figuring out if your search engine is lying to you about those modified peptides. Case study? That miserable region of histones where everything is conserved and everything can have multiple PTMs and – worst of all -people really truly care about which PTM is where!
- by MS ArticlesSometimes you need a very large sequence database, e.g. search all proteobacteria proteins. Mascot Server has no size limit. Search a database of hundreds of millions of protein sequences without running out of resources.https://www.matrixscience.com/blog/big-databases-and-large-peak-lists.html#proteomics #MassSpec
- by MS ArticlesChemistry – A European Journal, Volume 31, Issue 19, April 1, 2025.
- by MS ArticlesABSTRACT Background Atmospheric particulate matter (PM) is a complex mixture with a wide range of sources, but only a limited proportion can be identified by existing analytical techniques. Comprehensive two-dimensional gas chromatography–mass spectrometry (GC × GC-MS) couples the advantages on high resolution, sensitivity, and peak capacity on gas chromatography, together with the high mass accuracy and acquisition frequency of time-of-flight mass spectrometry […]
- by MS ArticlesWe have previously demonstrated that the transcription-dependent interaction of the promoter and terminator ends of a gene, which results in the formation of a gene loop, is facilitated by the interaction of the general transcription factor TFIIB with the CF1, CPF and Rat1 termination complexes. To further elucidate the protein-protein interactions that stabilize gene loop, we performed mass spectrometry of […]
- by MS ArticlesInterferon-induced antiviral proteins act on the first line of defence against viruses, including influenza A virus (IAV). Among those, the short isoform of Nuclear Receptor Coactivator 7 (NCOA7-AS) has been shown to inhibit IAV entry and more especially the fusion between endosomal and viral membranes. Ectopic expression of NCOA7-AS leads to the increased acidification of the endolysosomal pathway, putatively through […]
- by MS ArticlesRationale: Epilepsy presents significant sex-based disparities in prevalence and manifestation. Epidemiological studies reveal that epilepsy is more prevalent in males, with lesional types being more common, whereas idiopathic generalized epilepsies are more frequently observed in females. These differences stress the importance of considering sex-specific factors in epilepsy diagnosis, treatment, and mechanistic research using preclinical models. To elucidate potential molecular differences […]
- by MS ArticlesJournal of Proteome ResearchDOI: 10.1021/acs.jproteome.4c00742
- by MS ArticlesProtein complexes are essential for virtually all biological processes, yet their structural characterization remains a major challenge due to their heterogeneous, dynamic nature and the complexity of the proteome. Native top-down mass spectrometry (nTDMS) has emerged as a powerful tool for comprehensive structural characterization of purified protein complexes, but its application to endogenous protein complexes in the proteome is challenging […]
- by MS ArticlesJournal of the American Society for Mass SpectrometryDOI: 10.1021/jasms.4c00474
- by MS ArticlesBackground: While operative and perioperative care continues to improve for single ventricle congenital heart disease (SV), long-term morbidities and mortality remain high. Importantly, phosphodiesterase-5 inhibitor therapies (PDE5i) are increasingly used, however, little is known regarding the direct myocardial effects of PDE5i therapy in the SV population. Objectives: Our group has previously demonstrated that the failing SV myocardium is characterized by […]
- by MS ArticlesAnalytical ChemistryDOI: 10.1021/acs.analchem.4c06949