- 🎁 Season’s Greetings & GratitudeThanks for choosing us in 2025.Wishing you a peaceful holiday season and a successful new year — from our team to yours!#mswil #proteomics #LCMS #MassSpec #MassSpectrometry #Proteomics #Chemistry #BioMedical #Pharmancy #Metabolomics #Physics #MSWil #MakingScienceWork
- Mascot Newsletter, December 2025:NCBI nr FASTA replacement.Immunoregulation during pregnancy.Mascot Server as system service on Linux.https://www.matrixscience.com/nl/202512/newsletter.html#proteomics #massspec
- After a fair bit of frustration, our new excimer laser is installed! We have it coupled to an Element 2, and new laser plus sector magnet (rather than quadupole) mass spectrometry is a steep learning curve for me. Nice to spend the afternoon tinkering in the lab though.#LAICPMS #MassSpec #MPIC
- When raw data is processed into peak lists, there is a choice: how should peak intensity be calculated? Mascot Distiller defaults to peak area. The alternative, signal-to-noise (S/N), can be useful with detecting diagnostic ions.#proteomics #massspechttps://www.matrixscience.com/blog/peak-list-arcana-area-vs-signal-to-noise.html
- Mascot Newsletter, November 2025:Top-3 quant with DDA-PASEF.ZooMS peptide markers for South American Xenarthrans.Migrating from Windows 10 to Linux could extend the lifetime of your hardware.https://www.matrixscience.com/nl/202511/newsletter.html#proteomics #massspec
- The NCBI nr FASTA file of protein sequences is no longer updated. We've summarised instructions for creating it from the BLAST database — or you may be better off using TrEMBL.https://www.matrixscience.com/blog/replacements-for-ncbi-nr.html#proteomics #massspec
- Mascot Newsletter, October 2025:Spectrum-centric DIA scoring.Molecular mechanisms of SBK2 kinase on the heart.Windows update issue with IIS (resolved).https://www.matrixscience.com/nl/202510/newsletter.html#proteomics #massspec
- Der Mann hat was neues für #Lupus gefunden – oder wie @kabalak selbst sagen würde:In conclusion, this study uncovers a new dimension of immune crosstalk: a proteolytic plasma network that generates immunoactive fragments with intrinsic self-regulatory capabilities to modulate #inflammation and tissue injury in complex disease contexts. Deciphering these immunoactivities may pave the way for innovative diagnostic and therapeutic strategies in complement-driven pathologies, potentially benefiting a wide range of inflammatory and autoimmune diseases.#AutoimmuneDiseases #InflammatoryDisease #Science #SLE #proteomics #MassSpec #TeamMassSpec #LupusResearch https://www.embopress.org/doi/full/10.1038/s44318-025-00598-8
- Next @denbi.bsky.social #training course: 🔬🚀 OpenMS Training & Open House 2025 in Toronto!📅 Nov 9 | 10AM–2PM | 🏛️ U of TorontoHands-on sessions in #proteomics & #metabolomics: OpenMS, pyOpenMS, WebApps, DIA, data viz & more.🤝 https://www.denbi.de/training-courses-2025/1965-openms-training-open-house-2025#OpenMS #MassSpec #Bioinformatics
- 🚀 Registration is open for EuBIC-MS Winter School 2026! ❄️🧬📍 Harrachov, Czechia🎙️ Keynotes | 🛠️ Workshops | 🤝 NetworkingSupported by @deNBI. This event is a must for anyone in #Bioinformatics, #Proteomics, or #Metabolomics.🔗 https://eubic-ms.org/events/2026-winter-school/#EuBIC2026 #MassSpec @eubic-ms.org
- Mascot Daemon can export protein level quant intensities for replicate LFQ, SILAC and iTRAQ/TMT. The latest version can also export intensity values calculated using the "Top-3" method, illustrated here with DDA-PASEF data.https://www.matrixscience.com/blog/top-3-quantitation-summary-in-mascot-daemon-3-using-dda-pasef.html#proteomics #massspec
- I just submitted my manuscript for November's meeting of the NVMS!#MassSpec #Proteomics #Bioinformatics @magnuspalmblad @Stephanhacker2 https://www.nvms.nl/
- 🎁 Season’s Greetings & GratitudeThanks for choosing us in 2025.Wishing you a peaceful holiday season and a successful new year — from our team to yours!#mswil #proteomics #LCMS #MassSpec #MassSpectrometry #Proteomics #Chemistry #BioMedical #Pharmancy #Metabolomics #Physics #MSWil #MakingScienceWork
- Mascot Newsletter, December 2025:NCBI nr FASTA replacement.Immunoregulation during pregnancy.Mascot Server as system service on Linux.https://www.matrixscience.com/nl/202512/newsletter.html#proteomics #massspec
- After a fair bit of frustration, our new excimer laser is installed! We have it coupled to an Element 2, and new laser plus sector magnet (rather than quadupole) mass spectrometry is a steep learning curve for me. Nice to spend the afternoon tinkering in the lab though.#LAICPMS #MassSpec #MPIC
- When raw data is processed into peak lists, there is a choice: how should peak intensity be calculated? Mascot Distiller defaults to peak area. The alternative, signal-to-noise (S/N), can be useful with detecting diagnostic ions.#proteomics #massspechttps://www.matrixscience.com/blog/peak-list-arcana-area-vs-signal-to-noise.html
- Mascot Newsletter, November 2025:Top-3 quant with DDA-PASEF.ZooMS peptide markers for South American Xenarthrans.Migrating from Windows 10 to Linux could extend the lifetime of your hardware.https://www.matrixscience.com/nl/202511/newsletter.html#proteomics #massspec
- The NCBI nr FASTA file of protein sequences is no longer updated. We've summarised instructions for creating it from the BLAST database — or you may be better off using TrEMBL.https://www.matrixscience.com/blog/replacements-for-ncbi-nr.html#proteomics #massspec
- Mascot Newsletter, October 2025:Spectrum-centric DIA scoring.Molecular mechanisms of SBK2 kinase on the heart.Windows update issue with IIS (resolved).https://www.matrixscience.com/nl/202510/newsletter.html#proteomics #massspec
- Der Mann hat was neues für #Lupus gefunden – oder wie @kabalak selbst sagen würde:In conclusion, this study uncovers a new dimension of immune crosstalk: a proteolytic plasma network that generates immunoactive fragments with intrinsic self-regulatory capabilities to modulate #inflammation and tissue injury in complex disease contexts. Deciphering these immunoactivities may pave the way for innovative diagnostic and therapeutic strategies in complement-driven pathologies, potentially benefiting a wide range of inflammatory and autoimmune diseases.#AutoimmuneDiseases #InflammatoryDisease #Science #SLE #proteomics #MassSpec #TeamMassSpec #LupusResearch https://www.embopress.org/doi/full/10.1038/s44318-025-00598-8
- Next @denbi.bsky.social #training course: 🔬🚀 OpenMS Training & Open House 2025 in Toronto!📅 Nov 9 | 10AM–2PM | 🏛️ U of TorontoHands-on sessions in #proteomics & #metabolomics: OpenMS, pyOpenMS, WebApps, DIA, data viz & more.🤝 https://www.denbi.de/training-courses-2025/1965-openms-training-open-house-2025#OpenMS #MassSpec #Bioinformatics
- 🚀 Registration is open for EuBIC-MS Winter School 2026! ❄️🧬📍 Harrachov, Czechia🎙️ Keynotes | 🛠️ Workshops | 🤝 NetworkingSupported by @deNBI. This event is a must for anyone in #Bioinformatics, #Proteomics, or #Metabolomics.🔗 https://eubic-ms.org/events/2026-winter-school/#EuBIC2026 #MassSpec @eubic-ms.org
- Mascot Daemon can export protein level quant intensities for replicate LFQ, SILAC and iTRAQ/TMT. The latest version can also export intensity values calculated using the "Top-3" method, illustrated here with DDA-PASEF data.https://www.matrixscience.com/blog/top-3-quantitation-summary-in-mascot-daemon-3-using-dda-pasef.html#proteomics #massspec
- I just submitted my manuscript for November's meeting of the NVMS!#MassSpec #Proteomics #Bioinformatics @magnuspalmblad @Stephanhacker2 https://www.nvms.nl/