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    (RSS) (BioRxiv All) Discovery of CDK4-selective molecular glue degraders by high-throughput proteomics: Molecular glue degraders (MGDs) are proximity-inducing molecules that promote the destruction of disease-causing proteins by stabilizing novel interfaces between E3 ubiquitin ligases and target proteins. The rational design of MGDs remains exceptionally challenging, historically relying on serendipitous discoveries. Here, we deployed a… https://www.biorxiv.org/content/10.64898/2026.06.19.733443v1?rss=1&utm_source=dlvr.it&utm_medium=mastodon #BioRxiv #MassSpecRSS
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    RSS Feed: (Analyst) Metabolic profiles of MK-3984 (SARM) in zebrafish using Ultra High Performance liquid chromatography Q Extractive HF Hybrid Quadrupole Orbitrap mass spectrometry (UPLC-QE-HF-MS) for doping control: Analyst, 2026, Accepted ManuscriptDOI: 10.1039/D6AN00421K, PaperYang Liu, Zhengyang Guo, Siyang Qin, Xuxiao Zhao, Xiaopei Wu, Jing Jing, Jianghai LuIn this study, the metabolic profiles of MK-3984, a selective… http://pubs.rsc.org/en/Content/ArticleLanding/2026/AN/D6AN00421K?utm_source=dlvr.it&utm_medium=mastodon (RSS) /RSS Feed #MassSpecRSS #analyst
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    (RSS) (CEJ) Probing the Influence of Sulfur–Aromatic Interactions on the Electronic Structure of Gas‐Phase Peptides: Chemistry – A European Journal, Volume 32, Issue 23, 16 June 2026. https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/chem.202503483?af=R&utm_source=dlvr.it&utm_medium=mastodon (/CEJ)
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    (RSS) (CEJ) Synthesis of Oligonucleotide Conjugates Employing a Diselenide Linker: Chemistry – A European Journal, EarlyView. https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/chem.71277?af=R&utm_source=dlvr.it&utm_medium=mastodon (/CEJ)
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    (RSS) (BioRxiv All) The dynamic inositol phosphate network during development in Drosophila melanogaster: Inositol phosphates (InsPs) and inositol pyrophosphates (PP-InsPs) are key regulators of cellular signaling and metabolism, yet developmental changes in the InsP/PP-InsP network in eukaryotic systems remain poorly understood. Here, we combine isomer-resolved capillary electrophoresis-mass spectrometry (CE-MS) with genetic perturbations to… https://www.biorxiv.org/content/10.64898/2026.06.18.733221v1?rss=1&utm_source=dlvr.it&utm_medium=mastodon #BioRxiv #MassSpecRSS
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    (RSS) (Talanta) Online solid-phase extraction coupled to liquid chromatography-tandem mass spectrometry for fungicide translocation studies in soybean plants: Publication date: 1 December 2026Source: Talanta, Volume 310Author(s): Eliézer de Oliveira, Carla Beatriz Grespan Bottoli https://www.sciencedirect.com/science/article/pii/S003991402600809X?dgcid=rss_sd_all&utm_source=dlvr.it&utm_medium=mastodon #Talanta #MassSpecRSS
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    (RSS) Scaling covalent ligand discovery through dynamic combinatorial library-versus-proteome screening https://www.nature.com/articles/s41467-026-74672-y?utm_source=dlvr.it&utm_medium=mastodon #nature #MassSpecRSS
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    (RSS) (J Mass Spectrom) In Memory of Prof. Günter Allmaier (1956–2022): Journal of Mass Spectrometry, Volume 61, Issue 7, July 2026. https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/jms.70074?af=R&utm_source=dlvr.it&utm_medium=mastodon #JMassSpectrom #MassSpecRSS
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    (RSS) (BioRxiv All) Regional connectivity and partial residency of capelin (Mallotus villosus) in the Gulf of St. Lawrence inferred from otolith chemistry: Capelin (Mallotus villosus), a key forage fish in the Northwest Atlantic, links zooplankton to predators including commercial fishes, seabirds, and marine mammals, yet its life-cycle movements in the Gulf of St. Lawrence (GSL) remain poorly understood. Between 2022 and 2024, otoliths from 927… https://www.biorxiv.org/content/10.64898/2026.06.18.733096v1?rss=1&utm_source=dlvr.it&utm_medium=mastodon #BioRxiv #MassSpecRSS
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    (RSS) (RCM) Determination of Residual Nitrilase in Brivaracetam Using Characteristic Peptides by Liquid Chromatography–Mass Spectrometry: ABSTRACTRationaleNitrilases are widely used as biocatalysts in pharmaceutical manufacturing because of their high stereoselectivity and mild reaction conditions. However, residual nitrilase in final drug products may compromise product quality and safety, highlighting the need for… https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/rcm.70126?af=R&utm_source=dlvr.it&utm_medium=mastodon #RapidCommunMassSpectrom #MassSpecRSS
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    (RSS) (RCM) Bioanalysis of Ametryn by UHPLC‐MS3 Coupled With Multiple Fragmentation to Decrease Interference and Enhance Sensitivity: ABSTRACTRationaleAmetryn poses significant risks to aquatic ecosystems, but conventional MRM methods suffer from matrix interference and limited sensitivity. To overcome these limitations, we established a more selective and sensitive UHPLC-MS3 approach that effectively suppresses background… https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/rcm.70124?af=R&utm_source=dlvr.it&utm_medium=mastodon #RapidCommunMassSpectrom #MassSpecRSS
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    (RSS) (Angew Chem) Strain Engineering via W–O–Ru Interfacial Coupling to Suppress Lattice Oxygen Activation for Stable Acidic Water Electrolysis: Constructing atomically coupled W–O–Ru interfacial units on RuO2 triggers a dynamic strain evolution during the oxygen evolution reaction. An initial tensile strain secures structural stability, while a self-adjusting transition to interfacial compression optimizes catalytic activity. This dynamic… https://onlinelibrary.wiley.com/doi/10.1002/anie.7876559?af=R&utm_source=dlvr.it&utm_medium=mastodon (RSS) #AngewChem #MassSpecRSS

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