- (RSS) (BioRxiv All) Muscle spatial lipidomics identifies early ALS signatures in presymptomatic SOD1G93A mice: Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease whose diagnosis often remains delayed. Skeletal muscle is increasingly recognized as an early contributor to ALS pathology. Using lipid imaging mass spectrometry (LIMS) in Tibialis anterior muscle from hSOD1G93A mice across disease stages, we identified… https://www.biorxiv.org/content/10.64898/2026.07.08.737202v1?rss=1&utm_source=dlvr.it&utm_medium=mastodon #BioRxiv #MassSpecRSS
- (RSS) (J Proteom) Evaluation of pilocarpine effects on sweat proteome: Publication date: Available online 12 July 2026Source: Journal of ProteomicsAuthor(s): S. Wislet, C. Le Goff, Massonet Ph, S. Hody, J.L. Croisier, V. D’orio, J.F. Kaux, G. Mazzucchelli, R. Cloots https://www.sciencedirect.com/science/article/pii/S1874391926001120?dgcid=rss_sd_all&utm_source=dlvr.it&utm_medium=mastodon #MassSpecRSS
- (RSS) (J Proteom) Community-driven advances in computational mass spectrometry: The perspective of EuBIC-MS members: Publication date: Available online 11 July 2026Source: Journal of ProteomicsAuthor(s): Dirk Winkelhardt, Julia P. Schessner, Sven Berres, Alireza Nameni, Armin Soleymaniniya, Ayla Schröder, Caroline Jachmann, Douwe Schulte, Georg Wallmann, Henry Webel, Johannes Rainer, Katerina Nastou, Laurent Gatto, Magnus Palmblad, Maike Weber, Omar… https://www.sciencedirect.com/science/article/pii/S1874391926001119?dgcid=rss_sd_all&utm_source=dlvr.it&utm_medium=mastodon #MassSpecRSS
- (RSS) (BioRxiv All) onsite: An Integrated Framework for Phosphosite Localization and False Localization Rate Estimation: With the rapid development of mass spectrometry-based proteomics, the volume of phosphoproteomic data has increased substantially. However, accurate localization of phosphorylation sites and standardized statistical validation remain critical analytical bottlenecks. To address the lack of standardized cross-algorithm evaluation,… https://www.biorxiv.org/content/10.64898/2026.07.08.737157v1?rss=1&utm_source=dlvr.it&utm_medium=mastodon #BioRxiv #MassSpecRSS
- (RSS) (BioRxiv All) The most common epilepsy-causing mutation in EEF1A2 (E122K) perturbs the translation of specific transcripts but not the rate of global protein synthesis: Heterozygous de novo missense mutations in the EEF1A2 gene encoding translation elongation factor eEF1A2 result in neurodevelopmental disorders, typically characterised by early onset epilepsy and intellectual disability (ID). The E122K mutation is the most commonly reported… https://www.biorxiv.org/content/10.64898/2026.07.08.737232v1?rss=1&utm_source=dlvr.it&utm_medium=mastodon #BioRxiv #MassSpecRSS
- (RSS) (Biomed Chrom) Development and Validation of a UPLC–MS/MS for Determination of Loureirin D in Rat Plasma and Its Application to Pharmacokinetics: ABSTRACTLoureirin D is a bioactive dihydrochalcone isolated from Dracaena resin with very high therapeutic value. A sensitive and high-throughput ultra-performance liquid chromatography–mass spectrometry (UPLC–MS/MS) method was developed for the quantitative analysis of loureirin D in rat… https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/bmc.70547?af=R&utm_source=dlvr.it&utm_medium=mastodon #massSpecRSS #biomedchrom
- (RSS) (Biomed Chrom) Overcoming Stability Challenge During the Quantification of SHR6508 in Human Plasma by LC–MS/MS: ABSTRACTSHR6508, a novel calcimimetic agent, is currently being developed for treating secondary hyperparathyroidism in chronic kidney disease (CKD) patients requiring maintenance hemodialysis. For the purpose of quantifying SHR6508 in human plasma, a sensitive and reliable LC–MS/MS method was first developed and… https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/bmc.70555?af=R&utm_source=dlvr.it&utm_medium=mastodon #massSpecRSS #biomedchrom
- (RSS) (Angew Chem) Interstellar Ice Chemistry Yields Elusive Sulfinothioic Acid (HS(O)SH): Hot chemistry in cold ices reveals the previously elusive sulfinothioic acid molecule, HS(O)SH, prepared through nonequilibrium chemistry in low-temperature ices and identified with isomer selective photoionization reflectron time-of-flight mass spectrometry combined with isotopic labeling.ABSTRACTLow-oxidation-state sulfur oxyacids are key… https://onlinelibrary.wiley.com/doi/10.1002/anie.8731327?af=R&utm_source=dlvr.it&utm_medium=mastodon (RSS) #AngewChem #MassSpecRSS
- (RSS) (TrAC) Generative AI for environmental mass spectrometry: Opportunities and challenges: Publication date: October 2026Source: TrAC Trends in Analytical Chemistry, Volume 203Author(s): Wen Li, Bin Hu https://www.sciencedirect.com/science/article/pii/S0165993626003808?dgcid=rss_sd_all&utm_source=dlvr.it&utm_medium=mastodon #TrAC #MassSpecRSS
- (RSS) (Electrophoresis) Glycosylation Signatures of Thyroglobulin in Papillary Thyroid Carcinoma: This study investigated site-specific N-glycosylation alterations in thyroglobulin from patients with papillary thyroid carcinoma using nano-LC–MS/MS. Advanced bioinformatics and machine learning identified these unique glycan signatures, establishing the Asn1365-HexNAc(3)Hex(6) glycoform as a highly predictive diagnostic biomarker (AUC =… https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/elps.70130?af=R&utm_source=dlvr.it&utm_medium=mastodon #ElectrophoresisWiley #MassSpecRSS
- (RSS) (Electrophoresis) Chiral HPLC Separation of Phosphonothrixin and Phosphonate Derivatives and Electronic Circular Dichroism Characterization of the Isolated Enantiomers: Natural compound phosphonothrixin's herbicidal activity resides exclusively in its (S)-enantiomer, yet existing enantioselective syntheses are cumbersome, and direct chiral LC separation is hampered by the compound's high polarity, lack of aromatic groups, and… https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/elps.70128?af=R&utm_source=dlvr.it&utm_medium=mastodon #ElectrophoresisWiley #MassSpecRSS
- (RSS) (J Mass Spectrom) Evaluation of Surface Acoustic Wave Nebulization for NEMS Mass Spectrometry: Journal of Mass Spectrometry, Volume 61, Issue 8, August 2026. https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/jms.70084?af=R&utm_source=dlvr.it&utm_medium=mastodon #JMassSpectrom #MassSpecRSS
Mass spectrometry websites, social media, journal feeds, and other links and items of interest to the mass spectrometry community.
