Science

• Repair of DNA double-strand breaks leaves heritable impairment to genome function
  November 6, 2025 by Susanne Bantele, Irene Mordini, Alva Biran, Nicolas Alcaraz, Gijs Zonderland, Alice Wenger, Nils Krietenstein, Anja Groth, Jiri Lukas
  Science, Volume 390, Issue 6773, November 2025.
• Unlocking the potential of brassinosteroids: A path to precision plant engineering
  November 6, 2025 by Nemanja Vukašinović, Trevor M. Nolan, Eugenia Russinova
  Science, Volume 390, Issue 6773, November 2025.
• The role of organizations in fostering innovation
  November 6, 2025 by Imran Rasul
  Science, Volume 390, Issue 6773, November 2025.
• Preventing hypocontractility-induced fibroblast expansion alleviates dilated cardiomyopathy
  November 6, 2025 by Ross C. Bretherton, Isabella M. Reichardt, Kristin A. Zabrecky, Abigail Nagle, Logan R. J. Bailey, Darrian Bugg, Sasha Smolgovsky, Amy L. Gifford, Timothy S. McMillen, Alex J. Goldstein, Kristina B. Kooiker, Galina V. Flint, Amy Martinson, Jagdambika Gunaje, Franziska Koser, Elizabeth Plaster, Wolfgang A. Linke, Michael Regnier, Farid Moussavi-Harami, Nathan J. Sniadecki, Cole A. DeForest, Jennifer Davis
  Science, Volume 390, Issue 6773, November 2025.
• The anti-inflammatory activity of IgG is enhanced by co-engagement of type I and II Fc receptors
  November 6, 2025 by Andrew T. Jones, Alessandra E. Marino, Tetyana Martynyuk, Stylianos Bournazos, Jeffrey V. Ravetch
  Science, Volume 390, Issue 6773, November 2025.
• Direct targeting and regulation of RNA polymerase II by cell signaling kinases
  November 6, 2025 by Preeti Dabas, Meritxell B. Cutrona, Wojciech Rosikiewicz, Ryan P. Kempen, Patrick Rodrigues, John Bowling, Mollie S. Prater, Walter H. Lang, Adithi Danda, Zhi Yuan, Beisi Xu, Shondra M. Pruett-Miller, Gang Wu, Taosheng Chen, Aseem Z. Ansari
  Science, Volume 390, Issue 6773, November 2025.
• Adipogenin promotes the development of lipid droplets by binding a dodecameric seipin complex
  November 6, 2025 by Chao Li, Xue-Nan Sun, Jan-Bernd Funcke, Lauri Vanharanta, Xavier Prasanna, Kaitlynn Gov, Yan Li, Megan Virostek, Chanmin Joung, Nolwenn Joffin, Kristiina Kanerva, Abel Szkalisity, Waldemar Kulig, Leon Straub, Shiuhwei Chen, Joselin Velasco, Ayanna Cobb, Davide La Padula, May-Yun Wang, Toshiharu Onodera, Csaba Vörös, Dae-Seok Kim, Min Kim, Oleg Varlamov, Yang Li, Chen Liu, Andrea R. Nawrocki, Shangang Zhao, Da Young Oh, Zhao V. Wang, Ruth Gordillo, Joel M. Goodman, R. Max Wynn, W. Mike Henne, Ilpo Vattulainen, Yan Han, Elina Ikonen, Philipp E. Scherer
  Science, Volume 390, Issue 6773, November 2025.
• Deep generative models design mRNA sequences with enhanced translational capacity and stability
  November 6, 2025 by He Zhang, Hailong Liu, Yushan Xu, Haoran Huang, Yiming Liu, Jia Wang, Yan Qin, Haiyan Wang, Lili Ma, Zhiyuan Xun, Xuzhuang Hou, Timothy K. Lu, Jicong Cao
  Science, Volume 390, Issue 6773, November 2025.
• AI hallucinates because it’s trained to fake it till it makes it
  November 6, 2025 by Celina Zhao
  Science, Volume 390, Issue 6773, Page 558-559, November 2025.
• Thinning of DOE advisory bodies dismays researchers
  November 6, 2025 by Adrian Cho
  Science, Volume 390, Issue 6773, Page 555-556, November 2025.
• Biomedical philanthropy promises dramatic expansion and AI focus
  November 6, 2025 by Jon Cohen
  Science, Volume 390, Issue 6773, Page 552-553, November 2025.
• Protect Iraq’s Mesopotamian Marshes
  November 6, 2025 by Sarmad Dashti Latif
  Science, Volume 390, Issue 6773, Page 581-581, November 2025.
• FDA export restrictions threaten collaboration
  November 6, 2025 by Kaili Zhang, Jingyi Niu, and Zhiyong Li
  Science, Volume 390, Issue 6773, Page 452-452, November 2025.
• Cell signaling meets gene transcription
  November 6, 2025 by Richard Young
  Science, Volume 390, Issue 6773, Page 568-569, November 2025.
• Frankenstein and the problem of abandonment
  November 6, 2025 by Dov Greenbaum
  Science, Volume 390, Issue 6773, Page 578-579, November 2025.
• Cosmic dust reveals dynamic shifts in central Arctic sea-ice coverage over the past 30,000 years
  November 6, 2025 by Frank J. Pavia, Jesse R. Farmer, Laura Gemery, Thomas M. Cronin, Jonathan Treffkorn, Kenneth A. Farley
  Science, Volume 390, Issue 6773, Page 628-632, November 2025.
• River metabolism in the contiguous United States: A West of extremes
  November 6, 2025 by Taylor Maavara, Zimin Yuan, Andrew M. Johnson, Shuang Zhang, Kelly S. Aho, Craig B. Brinkerhoff, Laura A. Logozzo, Peter Raymond
  Science, Volume 390, Issue 6773, Page 622-627, November 2025.
• Multi-timescale frequency-phase matching for high-yield nonlinear photonics
  November 6, 2025 by Mahmoud Jalali Mehrabad, Lida Xu, Gregory Moille, Christopher J. Flower, Supratik Sarkar, Apurva Padhye, Shao-Chien Ou, Daniel G. Suárez-Forero, Mahdi Ghafariasl, Yanne Chembo, Kartik Srinivasan, Mohammad Hafezi
  Science, Volume 390, Issue 6773, Page 612-616, November 2025.
• The need for a global effort to attend to human neural organoid and assembloid research
  November 6, 2025 by Sergiu P. Pașca, Paola Arlotta, Philip Campbell, Alta Charo, John H. Evans, Nita Farahany, Fred H. Gage, Peter Godfrey-Smith, Insoo Hyun, Arnold R. Kriegstein, Lucia Melloni, Guo-Li Ming, Jonathan D. Moreno, Jeremy Sugarman, Sally Temple, Giuseppe Testa, and Henry T. Greely
  Science, Volume 390, Issue 6773, Page 574-577, November 2025.
• Shear-induced bubble nucleation in magmas
  November 6, 2025 by Olivier Roche, Jean-Michel Andanson, Alain Dequidt, Christian Huber, Olivier Bachmann, David Pinel
  Science, Volume 390, Issue 6773, Page 633-637, November 2025.

Related Journals

• Proceedings of the National Academy of Sciences