- by Shumaila Yousaf, Sadia Nawaz, Shagufta Saeed, Huma Mujahid, Azamt Ullah, Duaa Qaiser, Tahir MehmoodEuropean Journal of Mass Spectrometry, Ahead of Print. Diabetes mellitus (DM) is an onset metabolic illness in which hyperglycemia occurs due to acquired or inherited impaired insulin production and ineffective action. Diabetes is frequently managed with the use of drugs, which may have adverse consequences …
- by Abdulaziz Aljohari, Adham Bahian, Adnan A Kadi, AFM Motiur RahmanDepartment of Pharmaceutical Chemistry, 108788College of Pharmacy, King Saud University, Riyadh, Saudi ArabiaEuropean Journal of Mass Spectrometry, Ahead of Print. Chemical modification of the tyrosine kinase inhibitor (TKI) imatinib was performed to obtain the imatinib-N-oxide, followed by metabolic profiling to study the possibilities of forming potential reactive metabolites of both imatinib and imatinib-N-oxide. …
- by Viritha Bezawada, Padma Mogili, Sireesha Dodda, Srinivasa Rao PolaganiEuropean Journal of Mass Spectrometry, Volume 31, Issue 3-4, Page 87-93, June–August 2025. A high-performance liquid chromatography-tandem mass spectrometry method has been developed for the quantification of ertugliflozin in human plasma, employing ertugliflozin D5 as the internal standard. Methyl tertiary butyl ether-based liquid-liquid …
- by Ganiboy T Rakhmanov, Tursunali S Kholikov, Azim Sh Radjabov, Saida S Iskhakova, Dilshadbek T UsmanovEuropean Journal of Mass Spectrometry, Volume 31, Issue 3-4, Page 109-114, June–August 2025. The adsorption and surface ionization of cocaine molecules C17H21NO4(M: 303 Da) on the surface of oxidized tungsten was studied using the non-stationary voltage modulation method in a high-vacuum mass spectrometric setup employing a “black chamber,” all …
- by Namra Sarosh, Bilal RasulDepartment of Physics, University of Sargodha, Sargodha, PakistanEuropean Journal of Mass Spectrometry, Volume 31, Issue 3-4, Page 115-123, June–August 2025. The stability of gas-phase clusters primarily depends on their size, with magic numbers exhibiting exceptional conformal stability due to symmetric or closed-shell configurations. This phase is ideal for analyzing intrinsic properties, that is, as cluster …
- by M.S. Semynin, S.S. Rudyi, A.Y. Dubavik, A.V. Gavenchuk, A.V. Ivanov, D.P. Shcherbinin1International Research and Educational Center for Physics of Nanostructures, 65071ITMO University, Saint-Petersburg, RussiaEuropean Journal of Mass Spectrometry, Volume 31, Issue 3-4, Page 104-108, June–August 2025. In this paper, we develop and describe a technology for delivering micro- and nanoparticles from solutions into a linear quadrupole Paul trap using the paper spray method. The developed technology is based on electrospraying of colloids with the particles …
- by Ayesha Arshad, Shagufta Saeed, Muhammad Tayyab, Quratulain Maqsood, Tahir MehmoodEuropean Journal of Mass Spectrometry, Volume 31, Issue 3-4, Page 94-103, June–August 2025. The rapid increase in incidences of antibiotic resistance, as well as the severity of side effects associated with the synthetic drugs, have directed the researchers to focus on the natural reservoirs as an alternative to the available drugs. The aim of …
- by J Stuart Grossert, Robert L WhiteDepartment of Chemistry, 98609Dalhousie University, Halifax, Nova Scotia, CanadaEuropean Journal of Mass Spectrometry, Volume 31, Issue 3-4, Page 124-132, June–August 2025. Carboxylic acids containing anO-acetyl substituent were studied using tandem mass spectrometry (MS/MS). Decarboxylation was observed for deprotonatedO-acetylmandelic acid, whereas deprotonated acetoxyacetic acid and acetylsalicylic acid fragmented by …
- by Kevin M DownardInfectious Disease Responses Laboratory, Prince of Wales Clinical Research Sciences, 214154, NSW Sydney, AustraliaEuropean Journal of Mass Spectrometry, Volume 31, Issue 3-4, Page 73-78, June–August 2025. The nominal mass of amino acid residues calculated from their elemental compositions are defined by prime numbers far more often than chance, and such residues appear to play an important role in the formation and biology of proteins. It is proposed …
- by Thomas Powell, Martin Ebner, Andrew Creese272345Analytical Development, Immunocore Limited, Abingdon, UKEuropean Journal of Mass Spectrometry, Volume 31, Issue 3-4, Page 133-136, June–August 2025. Cross-linking mass spectrometry is rapidly becoming a choice method for determining a protein's higher-order structure as well as capturing inter-protein interactions. In particular, diazirene-based photo-activatable cross-linkers, such as sulfo-SDA have …
- by Bala Manikantha Adimoolam, Aruna Jangam, S Babu Dadinaboyina, Srinivas Ragampeta, Jagadeshwar Reddy ThotaEuropean Journal of Mass Spectrometry, Volume 31, Issue 3-4, Page 79-86, June–August 2025. Characterization of impurities is very important in drug chemistry and process development. Due to these transformation products (TPs), the drug may lose its stability, safety and efficiency. Hence, it is imperative to develop a selective analytical …
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