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  • Identification and characterization of unknown oxidation degradation products of Rimegepant by HPLC and triple quadrupole mass spectrometry
    by Narayana Reddy Godi, Sireesha Dodda, Nagavardhana Reddy Vanga, Kumarswamy Ummiti
    European Journal of Mass Spectrometry, Ahead of Print. Rimegepant is a calcitonin gene-related peptide receptor antagonist that has been licensed for migraine headache treatment in the United States, the European Union, the United Kingdom, Hong Kong, Australia, and Kuwait. The oxidation stress study of the …
  • LC-ESI-MS/MS method for the accurate quantification of eight nitrosamines in pharmaceutical products
    by Ibrahim Danis, Durisehvar Ozer Unal
    European Journal of Mass Spectrometry, Ahead of Print. In 2018, the Food and Drug Administration and the European Medicines Agency identified nitrosamine impurities in certain drugs, prompting detailed investigations by international regulatory authorities. According to ICH M7 (R1) guidelines, nitrosamines …
  • Increased preponderance of glutamatergic dysregulation in atypical facial pain
    by Tajdeen Faaheera Fathima, Ramya Suresh, Ramya Ramadoss, Sandhya Sundar, Suganya Panneer Selvam, Pratibha Ramani, Krishnaswamy Nitya, Kasi Rajan Hema Shree
    European Journal of Mass Spectrometry, Ahead of Print. Background:Orofacial pain, encompassing a broad spectrum of conditions, arises from the intricate interplay of sensory, cognitive, and emotional components. Accurate diagnosis and management are challenging due to the complexity of orofacial anatomy. …
  • Characterization of linear quadrupoles operated with amplitude-asymmetric sinusoidal waveforms
    by Alexander I. Ivanov, Alexey A. Sysoev, Andrew N. Konenkov, Nikolai V. Konenkov
    European Journal of Mass Spectrometry, Ahead of Print. The stability regions formed by the asymmetric sinusoidal shape of the periodic supply potential of the quadrupole mass filter are calculated, with the signal duty cycled=0.5. Two cases are considered, whenA1A2, whereA1andA2are the amplitudes of the …
  • Basics of utilizing NH[math] ions for accurate phthalate ester quantification via selected ion flow tube mass spectrometry in food
    by Manjeet BhatiaQuantumSIMM, Kangra, HP, India
    European Journal of Mass Spectrometry, Ahead of Print. Phthalate esters, frequently used as plasticizers in consumer products, raise concerns because of potential health effects. Using density functional theory (DFT) with B3LYP and 6-311++G(d, p) basis sets, their properties, such as dipole moment, …
  • Ion crystal size and structure in Paul traps
    by Appala Naidu Kotana, Atanu K Mohanty
    European Journal of Mass Spectrometry, Volume 30, Issue 5-6, Page 221-234, October–December 2024. This article presents a relationship between the size of an ion crystal in a Paul trap and the radio frequency potential applied on the central ring electrode. Using a simple and elegant derivation it has been shown that the distance of an ion in the …
  • Bioanalytical method development and validation of docetaxel and carvacrol in mice plasma using LC-QqQ-MS/MS
    by Shiva Kumar Gogikar, Sibu Sen, Sandeep Daravath, Mayur Aalhate, Srushti Mahajan, Mohd Aman Mohd Ateeq, Pankaj Kumar Singh, Amol G. Dikundwar
    European Journal of Mass Spectrometry, Volume 30, Issue 5-6, Page 235-245, October–December 2024. Present work describes the development of a liquid chromatography tandem mass spectrometry-based bioanalytical method for the reliable simultaneous quantification of docetaxel (DXL) and carvacrol (CVL) in the mice plasma. A rapid and sensitive …
  • Exploring the versatility of mass spectrometry: Applications across diverse scientific disciplines
    by Akhilesh Kumar Kuril245536Department of Pharmacy, Bhagwant University, Ajmer, Rajasthan, India
    European Journal of Mass Spectrometry, Volume 30, Issue 5-6, Page 209-220, October–December 2024. Mass spectrometry (MS) has become a pivotal analytical tool across various scientific disciplines due to its ability to provide detailed molecular information with high sensitivity and specificity. MS plays a crucial role in various fields, including drug …
  • Analysis of dimer and trimer complexes of the non-amyloidogenic rat islet amyloid polypeptide 21–37 by electrospray ionization-tandem mass spectrometry
    by Jin Young Lim, Seo Yeon Kim, Ho-Tae KimDepartment of Chemistry and Bioscience, 34975Kumoh National Institute of Technology, Gumi, Republic of Korea
    European Journal of Mass Spectrometry, Volume 30, Issue 5-6, Page 254-260, October–December 2024. The dimer and trimer structures of the non-amyloidogenic rat islet amyloid polypeptide 21–37 peptide, formed in an H2O/CH3OH (1% CH3COOH) solution were investigated using electrospray ionization-tandem mass spectrometry (ESI-MS/MS). The dissociation of …
  • Clustering of biphenyl oxamide ions by chiral recognition
    by Renata Kobetić, Tomislav Portada, Dario Dabić
    European Journal of Mass Spectrometry, Volume 30, Issue 5-6, Page 246-253, October–December 2024. Gels created by self-assembly of small organic molecules are dynamic soft materials that have unique properties and demanding characterization. Four chiral gelators, with two valinol- or leucinoloxamido arms attached to the 2,2′-positions of the …

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