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  • Peptide-Directed Folding of the Elusive RNA i-Motif
    by Lachlan Barton Cox
    Chem. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D6SC01203E, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Lachlan Barton Cox, Pall Thordarson, Felix RizzutoFolded RNA structures are increasingly being recognised as key regulators in biological processes, yet the RNA i-motif remains poorly characterised due to its low stability and lack of selective molecular…The content of this RSS Feed (c) The Royal Society of Chemistry
  • AccA from Neisseria gonorrhoeae provides a new framework for understanding periplasmic copper metallochaperones.
    by Samantha Firth
    Chem. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D5SC08738D, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Samantha Firth, William Earl, Denis Thaqi, YoungJin Hong, Charlotte O'Hern, Gemma Luscombe, Dalton Ngu, Zhenyao Luo, Chacko Jobichen, Bostjan Kobe, Alastair G McEwan, Karrera DjokoMany bacteria use copper (Cu) to drive key redox reactions and energy metabolism, and they often rely on metallochaperones to deliver Cu to Cu-dependent enzymes. However, why trafficking by metallochaperones…The content of this RSS […]
  • Chloride-Induced Easier Phase Transformation and Catalytic Synergy for Enhanced Seawater Splitting
    by Haibin Ma
    Chem. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D5SC09403H, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Haibin Ma, Yuxiang Jin, Xiaoyan Zhou, Yujie Cui, Yang Zhao, Chia-Yu Chang, Min-Hsin Yeh, Wei-Hsiang Huang, Erhong Song, Jiwei Ma, Hongfei ChengHydrogen production from sustainable seawater splitting technology is restricted by the side reactions of chlorine evolution and chlorine oxidation on anode. Different from the common catalyst design strategy, i.e., selecting…The content of this RSS Feed (c) The […]
  • Leveraging the Redox Activities of Cerium and Dibenzotetrathiafulvalene to Discover a Photo-Responsive Magnetic Material
    by Himanshu Gupta
    Chem. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D5SC08870D, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Himanshu Gupta, Ethan P Shapera, Xiaojuan Yu, Xiaoyu Wang, Patrick Smith, Pragati Pandey, Michael Gau, Stefan Minasian, Eva Zurek, Jochen Autschbach, James M. Kikkawa, Eric J. SchelterStimuli-responsive changes in lanthanide-based materials are a promising research direction. In this study, [DBTTF]4[Ce2Cl10] DBTTF = dibenzotetrathiafulvalene (1) was synthesized by a light-induced crystallization, where photo-oxidation of DBTTF enables formation…The content of […]
  • Homoleptic seven-coordinate Ti(0) and Zr(0) through a new stabilization mode
    by Ivan Antsiburov
    Chem. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D6SC00226A, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Ivan Antsiburov, Raphael Bühler, Johannes Stephan, Maxim Erdyakov, Christian Gemel, Samia Kahlal, Olivier Cador, Thierry Guizouarn, Jean-Yves Saillard, Karsten Meyer, Roland A. FischerThe stabilization of zero oxidation state group (IV) metal centers in readily accessible compounds on a preparative scale remains a significant challenge. Substituting hydrocarbon ligands in the precursor complexes [Ti(η6-toluene)2]…The content of this RSS Feed (c) […]
  • Decoupling Ion Size from Electrochemistry: Cation-Size-Independent Accommodation of Li+ to Cs+ in an Amorphous Sulfonamide Coordination Polymer
    by Robert Markowski
    Chem. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D6SC00585C, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Robert Markowski, Darsi Rambabu, Augustin ramackers, Alexandru VladUnderstanding how cation identity governs charge storage is critical for next-generation batteries beyond lithium. Here we show that the amorphous Ca-Zn-PTtSA coordination polymer functions as a universal host for reversible…The content of this RSS Feed (c) The Royal Society of Chemistry
  • Chemical Regulation of Carbonization Enables Structure-Tailored Hard Carbon Anodes from Recycled Polypropylene Separators
    by Mingyue Wang
    Chem. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D6SC00807K, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Mingyue Wang, Yue Wang, Na Li, Qing Zhong, Min Zhu, Dongyang Zhang, Shujiang DingThe high-value recycling of spent lithium-ion battery separators and the rational design of hard carbon anodes are critical for sustainable sodium-ion batteries. Herein, a sulfonation-induced crosslinking strategy is proposed to…The content of this RSS Feed (c) The Royal Society of Chemistry
  • A reflection on ‘A hydrazone-based covalent organic framework for photocatalytic hydrogen production’: teaching sponges new tricks
    by Andrés Rodríguez-Camargo
    Chem. Sci., 2026, Advance ArticleDOI: 10.1039/D6SC90032A, Commentary Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Andrés Rodríguez-Camargo, Bettina V. LotschIn celebration of our 15th anniversary and some of our most popular articles, Bettina Lotsch reflects on the area of catalysis with covalent organic frameworks, building on a seminal paper published in Chemical Science on this topic (Chem. Sci., 2014, https://doi.org/10.1039/C4SC00016A).To cite this article before page numbers are assigned, use the DOI form of citation […]
  • Delicate Molecular Design, Self-Assembly and Functional Applications of Chiral Cyclophanes
    by Yiming Zhang
    Chem. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D5SC09932C, Review Article Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Yiming Zhang, Hongzhe Jia, Lijin Xu, Minghua Liu, Guanghui OuyangChiral cyclophanes represent a unique supramolecular architecture that integrates chiral cavities with luminescent properties, enabled by their precisely controlled interchromophoric orientation, distance, and asymmetry. These features confer exceptional chiral recognition…The content of this RSS Feed (c) The Royal Society of Chemistry
  • Ring-opening decarbonylative C(sp3)–C(sp3) cross-electrophile coupling of cyclic imides with unactivated alkyl chlorides
    by Niklas J. Lentelink
    Chem. Sci., 2026, Advance ArticleDOI: 10.1039/D6SC00815A, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Niklas J. Lentelink, Peter M. F. Pânzar, Nathalie A. V. Rowlinson, Bill MorandiSelective nickel-mediated endocyclic N–C(O) activation establishes cyclic imides as competent electrophiles in decarbonylative C(sp3)–C(sp3) cross-electrophile coupling with unactivated alkyl chlorides.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry
  • Simulating enzyme catalysis with electrostatically embedded machine learning potentials
    by Valentin Gradisteanu
    Chem. Sci., 2026, Advance ArticleDOI: 10.1039/D6SC01156J, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Valentin Gradisteanu, Elliot W. Chan, Lester Hedges, Meritxell Malagarriga, Rolf David, Miguel de la Puente, Damien Laage, Iñaki Tuñón, Marc W. van der Kamp, Kirill ZinovjevEnzyme catalysis can be simulated accurately and efficiently by coupling machine-learned potentials trained on gas-phase data to the environment (ML/MM) using electrostatic machine-learning embedding (EMLE).To cite this article before page numbers are assigned, […]
  • Amino acid appended supramolecular self-associating amphiphiles demonstrate dual activity against both MRSA and ovarian cancer
    by Precious I. A. Popoola
    Chem. Sci., 2026, Advance ArticleDOI: 10.1039/D5SC03376D, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Precious I. A. Popoola, Thomas L. Allam, Rebecca J. Lilley, Chandni Manwani, Olivia B. Keers, Junyang Tan, Kylie Yang, Yifan Long, Ewan R. Clark, Lisa J. White, Kira L. F. Hilton, Jennifer Rankin, Jennifer Baker, Charlotte Bennett, Hollie B. Wilson, Evelyn R. Morton, Alvaro Keskküla, Bethany Martin, Christopher O'Connor, J. Mark Sutton, Charlotte K. Hind, Michelle D. Garrett, […]
  • Deep excitation afterglow luminescent probes for biomedical applications
    by Yiqian Hao
    Chem. Sci., 2026, Advance ArticleDOI: 10.1039/D5SC09312K, Perspective Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Yiqian Hao, Yuxia Liu, Xi Liu, Siyue Ma, Chao Wang, Qing Miao, Linlin Wang, Pu Chen, Dongliang Su, Jonathan L. Sessler, Bo Tang, Tony D. James, Guang ChenAfterglow imaging provides continuous deep luminescence when excited by NIR-light, X-ray or ultrasound. Avoiding autofluorescence, improving imaging sensitivity and signal-to-background ratio.To cite this article before page numbers are assigned, use the DOI […]
  • Photoluminescence of ligand-protected gold nanoclusters: progress in experimental and theoretical studies
    by Kang Li
    Chem. Sci., 2026, Advance ArticleDOI: 10.1039/D6SC00001K, Review Article Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Kang Li, Pu Wang, Yong PeiExperimental enhancement and theoretical mechanisms of photoluminescence in ligand-protected Au nanoclusters.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry
  • Computational Study of the Effect of Lewis Base Additives and Molecular Spin State in SmI2-Chemistry
    by Song Yu
    Chem. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D5SC08336B, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Song Yu, Ciro Romano, David John Procter, Nikolas KaltsoyannisSmI2 has become a crucial reagent in organic chemistry due to its ability to facilitate single-electron transfer (SET) reactions under mild conditions, enabling the construction of complex molecular architectures. Its…The content of this RSS Feed (c) The Royal Society of Chemistry
  • Selenol-containing two-dimensional perovskite promotes visible-light-driven selective reduction of unsaturated ketones
    by Wenxuan Li
    Chem. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D5SC09706A, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Wenxuan Li, Lihao Liao, Guoying Yao, Jialong Liu, Yilan Zhang, Jingpeng Li, Wangzhen Qiu, Tao Zeng, Xiaodan Zhao, Zhenyu YangSemiconductors have shown growing promise for photocatalytic reactions due to their tunable band structures and efficient charge separation capabilities. Among them, metal halide perovskites (MHPs) have emerged as particularly attractive…The content of this RSS Feed (c) The Royal Society […]
  • Near-infrared (NIR)-responsive activation of Ru-benziphthalocyanine complexes via singlet-triplet transition
    by Orie Takayama
    Chem. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D5SC09646D, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Orie Takayama, Naoyuki Toriumi, Kenjiro Hanaoka, Masanobu UchiyamaNear-infrared (NIR) light-responsive molecules are important tools in life sciences due to high tissue transparency and low phototoxicity in this wavelength region. However, conventional compounds are generally activated via S0–S1…The content of this RSS Feed (c) The Royal Society of Chemistry
  • Metal-Centered X-ray Absorption and Emission Spectroscopy of Iron Corroles: Implications for Ligand Non-Innocence †
    by Meiyuan Guo
    Chem. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D6SC00669H, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Meiyuan Guo, Abraham Alemayehu, Augustin Braun, Sang-Jun Lee, Dimosthenis Sokaras, Edward I. Solomon, Abhik Ghosh, Thomas KrollDetermining the electronic structure of transition metal complexes with non-innocent ligands is challenging, both experimentally and theoretically. In this study, we investigate the electronic structure of iron corrole nitrosyl (Fe[TPC](NO),…The content of this RSS Feed (c) The Royal Society of Chemistry
  • Photoinduced intramolecular S-α-C(sp3)–H functionalization enabled by an electron donor–acceptor complex-Mediated radical relay
    by Tiantian Xu
    Chem. Sci., 2026, Advance ArticleDOI: 10.1039/D6SC01281G, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Tiantian Xu, Ran Hong, Tong Lu, Denghua Zhu, Jiong Yu, Min Wang, Pinhua LiWe describe a consecutive reaction of 2-alkynylthioanisoles and 4-cyanopyridine enabled by EDA complex photoactivation, which facilitates the sequential S-α-C(sp3)–H bond activation, cyclization and radical coupling under mild conditions.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of […]
  • Why and When Does Lattice Oxygen Participate in Oxygen Evolution?
    by Arun Karmakar
    Chem. Sci., 2026, Accepted ManuscriptDOI: 10.1039/D6SC00812G, Perspective Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Arun Karmakar, Asha K Satheesan, Subrata KunduWhy does lattice oxygen contribute to the oxygen evolution reaction (OER) in some oxides and hydroxides, while remaining completely inactive in others that seem to have similar electronic properties? This…The content of this RSS Feed (c) The Royal Society of Chemistry

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