Science

• Rapid directed evolution guided by protein language models and epistatic interactions
  May 7, 2026 by Vincent Q. Tran, Matthew Nemeth, Liam J. Bartie, Sita S. Chandrasekaran, Alison Fanton, Hyungseok C. Moon, Brian L. Hie, Silvana Konermann, Patrick D. Hsu
  Science, Volume 392, Issue 6798, May 2026.
• A molecule with half-Möbius topology
  May 7, 2026 by Igor Rončević, Fabian Paschke, Yueze Gao, Leonard-Alexander Lieske, Lene A. Gödde, Stefano Barison, Samuele Piccinelli, Alberto Baiardi, Ivano Tavernelli, Jascha Repp, Florian Albrecht, Harry L. Anderson, Leo Gross
  Science, Volume 392, Issue 6798, May 2026.
• Tuft dendrites in frontal motor cortex enable flexible learning
  May 7, 2026 by Eduardo Maristany de las Casas, Kris Killmann, Moritz Drüke, Lukas Münster, Christian Ebner, Robert Sachdev, Dieter Jaeger, Matthew E. Larkum
  Science, Volume 392, Issue 6798, May 2026.
• Erratum for the Report “The Antibacterial Lectin RegIIIγ Promotes the Spatial Segregation of Microbiota and Host in the Intestine”
  May 7, 2026
  Science, Volume 392, Issue 6798, May 2026.
• Intermetallic nanoassemblies potentiate systemic STING activation
  May 7, 2026 by Xingwu Zhou, Xiang Ling, Xiaoqi Sun, Ziye Wan, Tobias Dwyer, Timothy C. Moore, Quguang Li, Hannah E. Dobson, Qi Wu, Xiangbo Kong, Fang Xie, Xinran An, Jingyao Gan, Kaikai Wang, Young Seok Cho, Wang Gong, Katherine Dong, Jie Zhang, Mariko Takahashi, Cheng Xu, Swetha Kodamasimham, Jie Xu, Vilma Yuzbasiyan-Gurkan, Steven B. Chinn, Anna Schwendeman, Sharon C. Glotzer, Yu Leo Lei, James J. Moon
  Science, Volume 392, Issue 6798, May 2026.
• Human DHX29 detects nonoptimal codon usage to regulate mRNA stability
  May 7, 2026 by Fabian Hia, Yitong Wu, Masanori Yoshinaga, Sakurako Goto-Ito, Wakana Iwasaki, Koshi Imami, Hirotaka Toh, Peixun Han, Ting Cai, Takayuki Ohira, Akira Fukao, Daron M. Standley, Yuichi Shichino, Masaki Takegawa, Toshinobu Fujiwara, Tsutomu Suzuki, Shintaro Iwasaki, Michael C. Bassik, Takuhiro Ito, Osamu Takeuchi
  Science, Volume 392, Issue 6798, May 2026.
• Short RNA chaperones promote aggregation-resistant TDP-43 conformers to mitigate neurodegeneration
  May 7, 2026 by Katie E. Copley, Jocelyn C. Mauna, Helen L. Danielson, Qizan Chen, Busra Ozguney, Marilyn Ngo, Longxin Xie, Ashleigh Smirnov, Matt Davis, Leland Mayne, Miriam Linsenmeier, Jack D. Rubien, Cristian A. Bergmann, Bede Portz, Bo Lim Lee, Hana M. Odeh, Longsheng Lai, Yi-Wei Chang, Martina Hallegger, Jernej Ule, Piera Pasinelli, Yan Poon, Jeetain Mittal, Nicolas L. Fawzi, Ben E. Black, Christopher J. Donnelly, Brigid K. Jensen, James Shorter
  Science, Volume 392, Issue 6798, May 2026.
• Competitive reactivity drives size- and composition-focusing in multimetallic nanocrystals
  May 7, 2026 by Jeesoo Yoon, Jinwon Oh, Dongjun Kim, Pin-Hung Chung, NaHyeon Hong, Jake Heinlein, Carlos Lizandara-Pueyo, Roel S. Sánchez-Carrera, Jungwon Park, Hee-Tae Jung, Matteo Cargnello
  Science, Volume 392, Issue 6798, May 2026.
• Magic mushroom compound shows promise against cocaine addiction
  May 7, 2026 by Rachel Nuwer
  Science, Volume 392, Issue 6798, Page 570-571, May 2026.
• Ferrimagnetism of ultracold fermions in a multiband Hubbard system
  May 7, 2026 by Martin Lebrat, Anant Kale, Lev Haldar Kendrick, Muqing Xu, Youqi Gang, Alexander Nikolaenko, Pietro M. Bonetti, Subir Sachdev, Markus Greiner
  Science, Volume 392, Issue 6798, Page 612-616, May 2026.
• Safeguard water infrastructure amid conflict
  May 7, 2026 by Xue Xiao and Yichen Tao
  Science, Volume 392, Issue 6798, Page 587-587, May 2026.
• The future of plant extinction
  May 7, 2026 by Rosa A. Scherson and Federico Luebert
  Science, Volume 392, Issue 6798, Page 581-582, May 2026.
• Building an oral peptide drug
  May 7, 2026 by Rebecca Buller and Joelle N. Pelletier
  Science, Volume 392, Issue 6798, Page 582-583, May 2026.
• Data-driven decisions in a fast-and-loose world
  May 7, 2026 by Jonathan Wai
  Science, Volume 392, Issue 6798, Page 585-585, May 2026.
• High risk of extinction across the flowering plant tree of life
  May 7, 2026 by Félix Forest, Ruth Brown, Sven Buerki, Jonathan F. Colville, Justin Moat, Eimear Nic Lughadha, Nisha R. Owen, Domitilla C. Raimondo, Malin Rivers, James Rosindell, Barnaby E. Walker, Steven P. Bachman, Sebastian Pipins, Rikki Gumbs, Matilda J. M. Brown
  Science, Volume 392, Issue 6798, Page 655-659, May 2026.
• Dynamic segmentation of the Sagaing fault
  May 7, 2026 by Mingqi Liu, Binhao Wang, Sezim E. Guvercin, Zhen Li, Teng Wang, Chuanjin Liu, Lingyun Ji, Sylvain Barbot
  Science, Volume 392, Issue 6798, Page 617-623, May 2026.
• Chaotic whale rescue shocks marine biologists
  May 7, 2026 by Martin Enserink
  Science, Volume 392, Issue 6798, Page 567-568, May 2026.
• Aging and the narrowing of scientific innovation
  May 7, 2026 by Haochuan Cui, Yiling Lin, Lingfei Wu, and James A. Evans
  Science, Volume 392, Issue 6798, Page 588-591, May 2026.
• Wildfire damages and the cost-effective role of forest fuel treatments
  May 7, 2026 by Frederik Strabo, Calvin Bryan, Matthew N. Reimer
  Science, Volume 392, Issue 6798, Page 629-635, May 2026.
• Forecasting volcanic eruptions across scales
  May 7, 2026 by Magnús T. Gudmundsson and Christopher J. Bean
  Science, Volume 392, Issue 6798, Page 578-579, May 2026.

Related Journals

• Proceedings of the National Academy of Sciences