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  • Stereoselective chemoenzymatic phytate transformations provide access to diverse inositol phosphate derivatives
    by Georg M Häner
    Chem. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5SC02844B, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Georg M Häner, Guizhen Liu, Esther Riemer, Nikolaus Jork, Klaus Ditrich, Ralf Greiner, Gabriel Schaaf, Henning Jacob JessenPhosphorylated myo-inositols (InsPs) are essential cytoplasmic signaling molecules, while their lipidated analogs (PtdInsPs) play a crucial role in membrane signaling. Stereoselective synthesis of these compounds has been achieved through various…The content of this RSS Feed (c) The Royal Society of Chemistry
  • Understanding the strain effect in alkaline hydrogen oxidation reaction over well-defined Ru surfaces: Insights into catalyst design
    by Zihan Guo
    Chem. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5SC02886H, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Zihan Guo, Yan Qiao, Mengfan Li, Zhenghe Gong, Jing-Wei Yu, Yanan Wang, Liang Zhao, Yang Li, Zehua Hu, Yangfan Lu, Hongwen HuangSurface strain has general impacts on the electronic structure and catalytic properties of catalyst surfaces. However, accurately deciphering the strain effect in many catalytic processes, such as the alkaline hydrogen…The content of this RSS Feed (c) The […]
  • Simulation of Ultrafast Transient Absorption Spectra of a Perylene-Based Light Harvesting Antenna
    by Royle Perez Castillo
    Chem. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5SC03157E, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Royle Perez Castillo, Victor Manuel Freixas Lemus, Aliezer Martinez-Mesa, Llinersy Uganda-Piña, Maxim F. Gelin, Sergei Tretiak, Sebastian Fernandez-AlbertiAtomistic simulations of photo-induced responses in artificial light-harvesting molecular systems help to reveal the mechanisms of ultrafast intramolecular energy transfer between individual chromophores. These light-induced processes mimic the primary events…The content of this RSS Feed (c) The Royal Society of Chemistry
  • Photosalient effect and reversible photochromic photoluminescence driven by cascade [2+2] cycloaddition reaction and water adsorption in 0D hybrid metal halide
    by Chudong Chen
    Chem. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5SC03344F, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Chudong Chen, Ziquan Li, Yonghong Xiao, Chenghao Ye, Jianwu Wei, Ruosheng Zeng, Qi Pang, Binbin LuoThe weak electronic coupling in ionic hybrid metal halides (HMHs) is conducive to integrating the photoactivity of organic components and mechanical properties of inorganic components. Therefore, HMHs can function as…The content of this RSS Feed (c) The Royal Society of Chemistry
  • Organic mechanoluminescent nanoparticles for biomedical applications
    by Christina Gu
    Chem. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5SC02526E, Review Article Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Christina Gu, Xiangping Liu, Brian Song, Wenliang Wang, Weilong He, Huiliang WangMechanoluminescence has emerged as a promising tool for biomedical applications, particularly when paired with ultrasound to enable remote activation. These mechanoluminescent systems have shown potential by offering remote control over…The content of this RSS Feed (c) The Royal Society of Chemistry
  • Biosynthesis of reveromycin derivatives by altering the regioselectivity of cytochrome P450revI
    by Ya Fen Yong
    Chem. Sci., 2025, Advance ArticleDOI: 10.1039/D5SC01355K, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Ya Fen Yong, Song Liu, Katsuyuki Sakai, Keisuke Fujiyama, Hiroshi Takagi, Yushi Futamura, Takeshi Shimizu, Hiroyuki Osada, Eugene Boon Beng Ong, Shunji TakahashiSpiroacetal rearrangement of reveromycin significantly reduces its biological potency. This study developed novel reveromycins with improved stability via P450 engineering and synthetic biological approaches.To cite this article before page numbers are assigned, use the DOI form […]
  • A Stable and Highly Selective Co-CeF3@Ni3N Sheet-on-Sheet Heterostructures for PET Electro-Upgrading and Hydrogen Production
    by Kuan Deng
    Chem. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5SC02685G, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Kuan Deng, Xuesong Liu, Peng Liu, Xing-Bin Lv, Wen Tian, Junyi JiElectro-upgrading of polyethylene terephthalate (PET) alkaline hydrolysate provides an energy-saving strategy towards green hydrogen and value-added anodic products, but their selectivity and stability under industrial-scale current densities (>200 mA cm-2)…The content of this RSS Feed (c) The Royal Society of Chemistry
  • Optimal photosynthesis of 2-benzothiazoles over hexaazatrinaphthylene-based porous aromatic frameworks
    by Jingjing Shao
    Chem. Sci., 2025, Advance ArticleDOI: 10.1039/D5SC00394F, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Jingjing Shao, He Wang, Xin Tao, Guangshan ZhuThe optimal photosynthesis of 2-arylbenzothiazoles over hexaazatrinaphthylene-based porous aromatic frameworks (HATN-PAFs) is achieved in high yields (up to 99%) with a broad substrate scope (20 examples) and good recyclability (10 cycles).To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed […]
  • Perfluoroarene-Arene Interaction Cocrystal of Perfluorocarbazoles toward IEF-Enhanced Photocatalysis
    by Wenbo Hu
    Chem. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5SC02837J, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Wenbo Hu, Bingxin Yuan, Heng LiThe photocatalytic generation of highly reactive oxygen species (ROS) such as H₂O₂ and ·OH, using molecular oxygen without sacrificial reagents or metal catalysts, is a significant challenge. To address this,…The content of this RSS Feed (c) The Royal Society of Chemistry
  • Difluoroenol Phosphinates as Difluoroenolate Surrogates: Synthesis and Applications in Defluorination and Deoxygenative Coupling
    by Miki B. Kurosawa
    Chem. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5SC03915K, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Miki B. Kurosawa, Shuhei Shimoyama, HIroki Tanaka, Junichiro YamaguchiWe report defluorinative and deoxygenative functionalization reactions of trifluoromethyl ketones mediated by the phospha-Brook rearrangement, offering a streamlined approach to selectively modifying fluorinated compounds. Trifluoromethyl ketones react with phosphine oxides…The content of this RSS Feed (c) The Royal Society of Chemistry
  • Mechanistic Insights into Spontaneous Redispersion of ZnO onto TiO2 in Water-Containing Environments†
    by Conghui Liu
    Chem. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5SC01637A, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Conghui Liu, Rongtan Li, Xiaohui Feng, Yuting Sun, Yamei Fan, Jiaxin Li, Qiang FuWater has a profound effect on surface structure and catalytic performance of numerous heterogeneous catalysts. Understanding the mechanism of structural evolution in water-containing reaction atmosphere is essential for the rational…The content of this RSS Feed (c) The Royal Society of Chemistry
  • Robust biomimetic MOF featuring a negative pocket for precise recognition of uranyl enabling an ultrahigh U/V selectivity and a rapid uranium extraction from seawater
    by Anni Ye
    Chem. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5SC02966J, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Anni Ye, Yuxuan Liu, Le Le Gong, Xianqing Xie, Feng LuoLow U/V selectivity and long extraction time remains the major obstacles in the field of uranium extraction from seawater, since both them can largely reduce the uranium extraction ability of…The content of this RSS Feed (c) The Royal Society of Chemistry
  • The Nuclear Targeted Type‑I Photosensitizer for Anti-Tumor Therapy
    by Zipeng Li
    Chem. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5SC02476E, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Zipeng Li, Wenkai Liu, Wanying Ma, Changyu Zhang, Jiangli Fan, Xiaojun PengPhotodynamic therapy (PDT) has attracted considerable interest in recent years as an effective and promising approach for tumor treatment. In particular, the nuclear-targeted type I photosensitizers (PSs) can directly damage…The content of this RSS Feed (c) The Royal Society of Chemistry
  • Bright and Water-Dispersible Membrane Probes Enable Visualization of Cellular Morphologies and Dynamics in Light-Scattering Tissues of Living Mice
    by Takumi Uemura
    Chem. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5SC03047A, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Takumi Uemura, Ryosuke Kawakami, Hitomi Seki, Satoshi Yoshida, Masamoto Murakami, Takeshi Imamura, Shingo Hadano, Shigeru Watanabe, Yosuke NikoFluorescent plasma membrane probes are indispensable tools for biological studies, enabling the visualization of the fine structure and dynamics of plasma membranes, and, by extension, the overall morphology of living…The content of this RSS Feed (c) The Royal Society of Chemistry
  • Hybrid Dual-electrolyte Electrochemical Cell for Glycerol Oxidation Upgrading
    by genxiang Wang
    Chem. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5SC02411K, Perspective Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.genxiang Wang, Junxiang Chen, Fen Qiao, Junfeng Wang, Zhenhai WenIntegrating the glycerol oxidation reaction (GOR) into aqueous electrochemical systems, such as fuel cells and electrolyzers, offers a promising strategy for utilizing the oxidized energy of glycerol to generate electricity…The content of this RSS Feed (c) The Royal Society of Chemistry
  • A Screening Approach Unveils an Unknown Mn2+-dependent Endopolyphosphatase Activity in Yeast
    by Sandra Moser
    Chem. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5SC02166A, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Sandra Moser, Gloria Hans, Anuj Shukla, Adolfo Saiardi, Samuel Bru, Asli Aras Taskin, Chris Meisinger, Henning Jacob JessenInorganic polyphosphate (polyP) is a ubiquitous biopolymer composed of multiple orthophosphates connected by energy-rich phosphoanhydride bonds. In organisms, polyP is digested by two types of enzymes: exopolyphosphatases, which shorten the…The content of this RSS Feed (c) The Royal Society of Chemistry
  • Stabilizing electrode-electrolyte interface for high-voltage Li||LiCoO2 cells by dual electrolyte additives
    by Jiwei Ding
    Chem. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5SC03120F, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Jiwei Ding, Chao Yang, Wenxi Hu, Xiaowei Liu, Anran Zhang, Deda Peng, Jin Han, Ya YouThe rechargeable cells Li||LiCoO2 are attractive due to their high energy density. However, the growth of lithium dendrites and the degradation of cathode under the high potential hinder their practical…The content of this RSS Feed (c) The Royal Society of Chemistry
  • Outstanding Reviewers for Chemical Science in 2024
    Chem. Sci., 2025, Advance ArticleDOI: 10.1039/D5SC90122G, Editorial Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.We would like to take this opportunity to highlight the Outstanding Reviewers for Chemical Science in 2024, as selected by the editorial team for their significant contribution to the journal.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry
  • Distinct oxygen reduction pathways for solar H₂O₂ production by regulating unsaturated bonds in covalent organic frameworks
    by Jieyu Yue
    Chem. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D5SC03270A, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Jieyu Yue, Zi-Xian Pan, Yan Guo, Peng Yang, Bo TangPhotocatalytic H2O2 generation via the two-electron oxygen reduction reaction (2e- ORR) is a highly sustainable approach, capable of proceeding via either a one-step or two-step 2e- ORR route. Nonetheless, precise…The content of this RSS Feed (c) The Royal Society of Chemistry
  • Segmented milli-fluidic crystallisation of paracetamol with in situ single-crystal X-ray diffraction
    by Karen Robertson
    Chem. Sci., 2025, Accepted ManuscriptDOI: 10.1039/D4SC08565E, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Karen Robertson, Mark R Warren, Lois E Wayment, Pollyanna Payne, C Daniel Scott, Chick C Wilson, Lucy K Saunders, Graeme Winter, Benjamin Williams, Lauren E. Hatcher, David Robert AllanSerial crystallography has revolutionalised our ability to analyse protein crystals; crystal structures can be uncovered by combining data from multiple crystals mitigating radiation damage through overexposure to the X-ray beam….The […]

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