Clinical Proteomics Most Recent Articles: Clinical Proteomics Most Recent Articles: Clinical Proteomics Proteomic characteristics and diagnostic potential of exhaled breath particles in patients with COVID-19 SARS-CoV-2 has been shown to predominantly infect the airways and the respiratory tract and too often have an unpredictable and different pathologic pattern compared to other respiratory diseases. Current clin… …
Tag Archives: Clinical_Proteomics
Discovery of novel glioma serum biomarkers by proximity extension assay
Clinical Proteomics Most Recent Articles: Clinical Proteomics Most Recent Articles: Clinical Proteomics Discovery of novel glioma serum biomarkers by proximity extension assay Gliomas are among the most malignant tumors, with a very poor prognosis. Early diagnosis is highly desirable since it can help implement more effective treatments for smaller tumors, which have not yet extensi… …
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Proteomic analysis of sialoliths from calcified, lipid and mixed groups as a source of potential biomarkers of deposit formation in the salivary glands
Clinical Proteomics Most Recent Articles: Clinical Proteomics Most Recent Articles: Clinical Proteomics Proteomic analysis of sialoliths from calcified, lipid and mixed groups as a source of potential biomarkers of deposit formation in the salivary glands Salivary stones, also known as sialoliths, are formed in a pathological situation in the salivary glands. So far, neither the …
Quantitative proteomics identifies and validates urinary biomarkers of rhabdomyosarcoma in children
Clinical Proteomics Most Recent Articles: Clinical Proteomics Most Recent Articles: Clinical Proteomics Quantitative proteomics identifies and validates urinary biomarkers of rhabdomyosarcoma in children Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma with poor prognosis in children. The 5-year survival rate for early RMS has improved, whereas it remains unsatisfactory for advanced patients. Urin… Na …
Potential biomarker proteins for aspiration pneumonia detected by shotgun proteomics using buccal mucosa samples: a cross-sectional case–control study
Clinical Proteomics Most Recent Articles: Clinical Proteomics Most Recent Articles: Clinical Proteomics Potential biomarker proteins for aspiration pneumonia detected by shotgun proteomics using buccal mucosa samples: a cross-sectional case–control study Aspiration pneumonia (AP), which is a major cause of death in the elderly, does present with typical symptoms in the early stages of onset, thus …
Proteomic analysis identifies dysregulated proteins and associated molecular pathways in a cohort of gallbladder cancer patients of African ancestry
Clinical Proteomics Most Recent Articles: Clinical Proteomics Most Recent Articles: Clinical Proteomics Proteomic analysis identifies dysregulated proteins and associated molecular pathways in a cohort of gallbladder cancer patients of African ancestry Gallbladder cancer (GBC) is a lethal cancer with a poor prognosis. The lack of specific and sensitive biomarkers results in delayed diagnosis with most …
Changes of serum IgG glycosylation patterns in rheumatoid arthritis
Clinical Proteomics Most Recent Articles: Clinical Proteomics Most Recent Articles: Clinical Proteomics Changes of serum IgG glycosylation patterns in rheumatoid arthritis RA is a common chronic and systemic autoimmune disease, and the diagnosis is based significantly on autoantibody detection. This study aims to investigate the glycosylation profile of serum IgG in RA patients … Xiaoyue …
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Integrating the serum proteomic and fecal metaproteomic to analyze the impacts of overweight/obesity on IBD: a pilot investigation
Clinical Proteomics Most Recent Articles: Clinical Proteomics Most Recent Articles: Clinical Proteomics Integrating the serum proteomic and fecal metaproteomic to analyze the impacts of overweight/obesity on IBD: a pilot investigation Inflammatory bowel disease (IBD) encompasses a group of chronic relapsing disorders which include ulcerative colitis (UC) and Crohn’s disease (CD). The incidences of IBD and …
Investigation on the mechanisms of human sperm DNA damage based on the proteomics analysis by SWATH-MS
Clinical Proteomics Most Recent Articles: Clinical Proteomics Most Recent Articles: Clinical Proteomics Investigation on the mechanisms of human sperm DNA damage based on the proteomics analysis by SWATH-MS Spermatozoa have the task of delivering an intact paternal genome to the oocyte and supporting successful embryo development. The detection of sperm DNA fragmentation (SDF) has been …
A proteomic profile of the healthy human placenta
Clinical Proteomics Most Recent Articles: Clinical Proteomics Most Recent Articles: Clinical Proteomics A proteomic profile of the healthy human placenta The placenta remains one of the least studied organs within the human body. Yet, placental dysfunction has been associated with various pregnancy complications leading to both maternal and fetal death and long… Samprikta Manna, Julia …
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Are the results from a multiplex proteomic assay and a conventional immunoassay for NT-proBNP and GDF-15 comparable?
Clinical Proteomics Most Recent Articles: Clinical Proteomics Most Recent Articles: Clinical Proteomics Are the results from a multiplex proteomic assay and a conventional immunoassay for NT-proBNP and GDF-15 comparable? We aimed to compare absolute plasma concentrations of N-terminal pro-brain natriuretic peptide (NT-proBNP) and growth differentiation factor 15 (GDF-15) obtained by a conventional immunoassay with the …
The novel biomarkers for assessing clinical benefits of continuous renal replacement therapy in pediatric sepsis: a pilot study
Clinical Proteomics Most Recent Articles: Clinical Proteomics Most Recent Articles: Clinical Proteomics The novel biomarkers for assessing clinical benefits of continuous renal replacement therapy in pediatric sepsis: a pilot study Continuous renal replacement therapy (CRRT) has been considered as an adjuvant therapy for sepsis. However, the novel biomarker to evaluate the benefits of CRRT is …
Combination of automated sample preparation and micro-flow LC–MS for high-throughput plasma proteomics
Clinical Proteomics Most Recent Articles: Clinical Proteomics Most Recent Articles: Clinical Proteomics Combination of automated sample preparation and micro-flow LC–MS for high-throughput plasma proteomics Non-invasive detection of blood-based markers is a critical clinical need. Plasma has become the main sample type for clinical proteomics research because it is easy to obtain and contains measurable protein …