- New approach methodologies for drug discovery
- Atomic unification in molecular AI
- The E3-ome gene-centric compendium reveals the human E3 ligase landscape
- Contextual computation by competitive protein dimerization networks
- Four centuries of commercial whaling eroded 11,000 years of population stability in bowhead whales
- Functional RNA splitting drove the evolutionary emergence of type V CRISPR-Cas systems from transposons
- Cell-type-specific transposon demethylation and TAD remodeling in aging mouse brain
- Ferritin aggregation cell engager for CAR T avidity engineering against refractory leukemias
- Metabolite-gated vascular contractility switch: OXGR1 activation mechanism enables agonist therapy for rosacea erythema
- Genetically encoded fluorescent reporters to visualize α-synuclein pathology in live brain
- Efficient amyloid-β degradation in Alzheimer’s disease using SPYTACs
- Restoring circadian rhythms in the hypothalamic paraventricular nucleus reverses aging biomarkers and extends lifespan in male mice
- Pyruvate is a natural suppressor of interferon signaling by inducing STAT1 protein pyruvylation
- Large-scale proteomics across neurological disorders uncovers biomarker panel and targets in multiple sclerosis
- The MicrobeAtlas database: Global trends and insights into Earth’s microbial ecosystems
- Nuclear speckles enable processing of RNA from GC-rich isochores
- Editing strigolactone hormone receptor for robust antiviral silencing in rice
- A GPX1-OSBPL8 axis mediates noncanonical in vivo ferroptosis and cancer growth suppression
- Unified modeling of 3D molecular generation via atomic interactions with PocketXMol
- Planetary microbiome structure and generalist-driven gene flow across disparate habitats
