Mass spectrometry analysis of phosphotyrosine‐containing proteins

Mass Spectrometry Reviews Wiley: Mass Spectrometry Reviews: Table of Contents Table of Contents for Mass Spectrometry Reviews. List of articles from both the latest and EarlyView issues. Mass spectrometry analysis of phosphotyrosine‐containing proteins Abstract Tyrosine phosphorylation is a crucial posttranslational modification that is involved in various aspects of cell biology and often has functions in …

Analysis of carbohydrates and glycoconjugates by matrix‐assisted laser desorption/ionization mass spectrometry: An update for 2019–2020

Mass Spectrometry Reviews Wiley: Mass Spectrometry Reviews: Table of Contents Table of Contents for Mass Spectrometry Reviews. List of articles from both the latest and EarlyView issues. Analysis of carbohydrates and glycoconjugates by matrix‐assisted laser desorption/ionization mass spectrometry: An update for 2019–2020 Abstract This review is the tenth update of the original article published in …

Measurement and utilization of the proteomic reactivity by mass spectrometry

Mass Spectrometry Reviews Wiley: Mass Spectrometry Reviews: Table of Contents Table of Contents for Mass Spectrometry Reviews. List of articles from both the latest and EarlyView issues. Measurement and utilization of the proteomic reactivity by mass spectrometry Abstract Chemical proteomics, which involves studying the covalent modifications of proteins by small molecules, has significantly contributed to …

Innovations in Applications of Mass Spectrometry Impact Many Fields of Science.

Mass Spectrometry Reviews Wiley: Mass Spectrometry Reviews: Table of Contents Table of Contents for Mass Spectrometry Reviews. List of articles from both the latest and EarlyView issues. Innovations in Applications of Mass Spectrometry Impact Many Fields of Science. Abstract I am pleased and honored that Dan Fabris has organized this special issue of reviews that …

Gene-metabolite annotation with shortest reactional distance enhances metabolite genome-wide association studies results

BioRxiv bioRxiv Subject Collection: Systems Biology This feed contains articles for bioRxiv Subject Collection "Systems Biology" Gene-metabolite annotation with shortest reactional distance enhances metabolite genome-wide association studies results Studies combining metabolomics and genetics, known as metabolite genome-wide association studies (mGWAS), have provided valuable insights into our understanding of the genetic control of metabolite levels. However, …

An improved rhythmicity analysis method using Gaussian Processes detects cell-density dependent circadian oscillations in stem cells

BioRxiv bioRxiv Subject Collection: Systems Biology This feed contains articles for bioRxiv Subject Collection "Systems Biology" An improved rhythmicity analysis method using Gaussian Processes detects cell-density dependent circadian oscillations in stem cells Detecting oscillations in time series datasets remains a challenging problem even after decades of research. Development of improved statistical algorithms, therefore, remains an …

DIP-MS: A novel ultra-deep interaction proteomics for the deconvolution of protein complexes

BioRxiv bioRxiv Subject Collection: Systems Biology This feed contains articles for bioRxiv Subject Collection "Systems Biology" DIP-MS: A novel ultra-deep interaction proteomics for the deconvolution of protein complexes Most, if not all, proteins are organized in macromolecular assemblies, which represent key functional units regulating and catalyzing the majority of cellular processes in health and disease. …

[ASAP] Machine Learning on Large-Scale Proteomics Data Identifies Tissue and Cell-Type Specific Proteins

Journal of Proteome Research Journal of Proteome Research: Latest Articles (ACS Publications) latest articles published in Journal of Proteome Research [ASAP] Machine Learning on Large-Scale Proteomics Data Identifies Tissue and Cell-Type Specific Proteins Journal of Proteome Research DOI: 10.1021/acs.jproteome.2c00644 Tine Claeys, Maxime Menu, Robbin Bouwmeester, Kris Gevaert, and Lennart Martens March 25, 2023 http://dx.doi.org/10.1021/acs.jproteome.2c00644

[ASAP] Modeling Lower-Order Statistics to Enable Decoy-Free FDR Estimation in Proteomics

Journal of Proteome Research Journal of Proteome Research: Latest Articles (ACS Publications) latest articles published in Journal of Proteome Research [ASAP] Modeling Lower-Order Statistics to Enable Decoy-Free FDR Estimation in Proteomics Journal of Proteome Research DOI: 10.1021/acs.jproteome.2c00604 Dominik Madej and Henry Lam March 25, 2023 http://dx.doi.org/10.1021/acs.jproteome.2c00604

[ASAP] OpenCustomDB: Integration of Unannotated Open Reading Frames and Genetic Variants to Generate More Comprehensive Customized Protein Databases

Journal of Proteome Research Journal of Proteome Research: Latest Articles (ACS Publications) latest articles published in Journal of Proteome Research [ASAP] OpenCustomDB: Integration of Unannotated Open Reading Frames and Genetic Variants to Generate More Comprehensive Customized Protein Databases Journal of Proteome Research DOI: 10.1021/acs.jproteome.3c00054 Noé Guilloy, Marie A. Brunet, Sébastien Leblanc, Jean-François Jacques, Marie-Pierre Hardy, …

[ASAP] Age-Dependent Serum Volatilomics of Milk and Yogurt Intake: A Randomized Crossover Study in Healthy Young and Older Men

Journal of Proteome Research Journal of Proteome Research: Latest Articles (ACS Publications) latest articles published in Journal of Proteome Research [ASAP] Age-Dependent Serum Volatilomics of Milk and Yogurt Intake: A Randomized Crossover Study in Healthy Young and Older Men Journal of Proteome Research DOI: 10.1021/acs.jproteome.2c00674 Hélène Yi Meng, Jinyoung Kim, Charlotte Fleuti, Pascal Fuchsmann, Sergio …

Learning Perturbation-specific Cell Representations for Prediction of Transcriptional Response across Cellular Contexts

BioRxiv bioRxiv Subject Collection: Systems Biology This feed contains articles for bioRxiv Subject Collection "Systems Biology" Learning Perturbation-specific Cell Representations for Prediction of Transcriptional Response across Cellular Contexts Pre-clinical and clinical scientific endeavours provide complementary perspectives on fundamental biological processes of translational value. Harnessing the information value on the totality of such knowledge requires novel …

Using interactive platforms to encode, manage and explore immune-related adverse outcome pathways

BioRxiv bioRxiv Subject Collection: Systems Biology This feed contains articles for bioRxiv Subject Collection "Systems Biology" Using interactive platforms to encode, manage and explore immune-related adverse outcome pathways We address the need for modelling and predicting adverse outcomes in immunotoxicology to improve non-clinical assessments of immunomodulatory therapy safety and efficacy. The integrated approach includes, first, …

Compromised beta-cell identity in type 2 diabetes

BioRxiv bioRxiv Subject Collection: Systems Biology This feed contains articles for bioRxiv Subject Collection "Systems Biology" Compromised beta-cell identity in type 2 diabetes Compromised beta-cell identity is emerging as an important contributor of beta-cell dysfunction in type 2 diabetes (T2D). Several studies suggest that hyperglycemia induces the inactivation of transcription factors involved in mature beta-cell …

Modeling transcriptional regulation of the cell cycle using a novel cybernetic-inspired approach

BioRxiv bioRxiv Subject Collection: Systems Biology This feed contains articles for bioRxiv Subject Collection "Systems Biology" Modeling transcriptional regulation of the cell cycle using a novel cybernetic-inspired approach Quantitative understanding of cellular processes, such as cell cycle and differentiation, is impeded by various forms of complexity ranging from myriad molecular players and their multilevel regulatory …

standard-GEM: standardization of open-source genome-scale metabolic models

BioRxiv bioRxiv Subject Collection: Systems Biology This feed contains articles for bioRxiv Subject Collection "Systems Biology" standard-GEM: standardization of open-source genome-scale metabolic models The field of metabolic modelling at the genome-scale continues to grow with more models being created and curated. This comes with an increasing demand for adopting common principles regarding transparency and versioning, …

Identification of novel smORFs and microprotein acting in response to rehydration of Nostoc flagelliforme

Proteomics (Wiley) Wiley: PROTEOMICS: Table of Contents Table of Contents for PROTEOMICS. List of articles from both the latest and EarlyView issues. Identification of novel smORFs and microprotein acting in response to rehydration of Nostoc flagelliforme Abstract Nostoc flagelliforme, a terrestrial cyanobacterium spread throughout arid and semi-arid areas, has been long known for its outstanding …

[ASAP] Normal Alpha-1-Antitrypsin Variants Display in Serum Allele-Specific Protein Levels

Journal of Proteome Research Journal of Proteome Research: Latest Articles (ACS Publications) latest articles published in Journal of Proteome Research [ASAP] Normal Alpha-1-Antitrypsin Variants Display in Serum Allele-Specific Protein Levels Journal of Proteome Research DOI: 10.1021/acs.jproteome.2c00833 Shelley Jager, Dario A. T. Cramer, and Albert J. R. Heck March 22, 2023 http://dx.doi.org/10.1021/acs.jproteome.2c00833

Proteomic analysis of liver tissue reveals Aeromonas hydrophila infection mediated modulation of host metabolic pathways in Labeo rohita

Journal of Proteomics ScienceDirect Publication: Journal of Proteomics ScienceDirect RSS Proteomic analysis of liver tissue reveals Aeromonas hydrophila infection mediated modulation of host metabolic pathways in Labeo rohita Publication date: 15 May 2023 Source: Journal of Proteomics, Volume 279 Author(s): Mehar Un Nissa, Nevil Pinto, Biplab Ghosh, Urvi Singh, Mukunda Goswami, Sanjeeva Srivastava March 22, …

Emergence of power-law distributions in protein-protein interaction networks through study bias

BioRxiv bioRxiv Subject Collection: Systems Biology This feed contains articles for bioRxiv Subject Collection "Systems Biology" Emergence of power-law distributions in protein-protein interaction networks through study bias Protein-protein interaction (PPI) networks have been found to be power-law-distributed, ie, in observed PPI networks, the fraction of nodes with degree k often follows a power-law (PL) distribution …