- (RSS) (Biomed Chrom) Pharmacokinetic, Bioavailability, and Excretion Study of Cistanoside A Following Intragastric and Intravenous Administration in Rats Using Ultra‐High Performance Liquid Chromatography–Tandem Mass Spectrometry: ABSTRACTCistanoside A (Cis A) has received more attention because of its potential in the treatment of osteoporosis. However, its in vivo process remains unknown. In this study, a simple liquid… https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/bmc.70508?af=R&utm_source=dlvr.it&utm_medium=mastodon #massSpecRSS #biomedchrom
- (RSS) (BioRxiv All) Integrating mass spectrometry with Nanopore direct RNA sequencing for de novo modification profiling of bacteriophage MS2: RNA modifications contribute to the regulatory and structural complexity of RNA molecules, influencing key biological processes. Nanopore direct RNA sequencing (DRS) enables the detection of these modifications at single-molecule resolution without chemical conversion. Oxford Nanopore Technologies recently… https://www.biorxiv.org/content/10.64898/2026.06.01.729303v1?rss=1&utm_source=dlvr.it&utm_medium=mastodon #BioRxiv #MassSpecRSS
- RSS Feed: (Analyst) Synthesis of Rhodamine B Hydrazine Derivatives and Their Application in Glycan Analysis: Analyst, 2026, Accepted ManuscriptDOI: 10.1039/D6AN00299D, PaperYu-Nan Chen, Xiao-Long Hou, Ying Liu, Xuyang Shen, Yi-xuan Gu, Yue Yu, Xin Zheng, Ying-Lin Zhou, Xinxiang ZhangDue to the high molecular weight and polarity, glycans suffer low ionization efficiency in electrospray ionization mass spectrometry (ESI-MS). It is… http://pubs.rsc.org/en/Content/ArticleLanding/2026/AN/D6AN00299D?utm_source=dlvr.it&utm_medium=mastodon (RSS) /RSS Feed #MassSpecRSS #analyst
- RSS Feed: (Analyst) Ultra-performance convergence chromatography tandem mass spectrometry strategy for quantification of monodisperse polyethylene glycol polymers coupled with multiple fragmentation to enhance sensitivity: Analyst, 2026, Accepted ManuscriptDOI: 10.1039/D6AN00305B, PaperJiarui Zhang, Hui Miao, Jiale Liu, Xinyue Zhou, Yue Deng, Shuang Feng, Yalin Xi, Meiyun Shi, Lei YinAccurate quantification of hydrophilic… http://pubs.rsc.org/en/Content/ArticleLanding/2026/AN/D6AN00305B?utm_source=dlvr.it&utm_medium=mastodon (RSS) /RSS Feed #MassSpecRSS #analyst
- (RSS) (BioRxiv All) Histone succinylation directly inhibits Jumonji domain demethylases and stabilizes repressive chromatin states: Herein we uncover a relationship between histone succinylation and Jumonji (JmjC) domain-containing histone demethylases. We used quantitative proteomics and peptide pull-down assays to identify JmjC demethylases as candidate interactors with succinylated histone peptides. Succinyl-lysine peptides bind and inhibit the… https://www.biorxiv.org/content/10.64898/2026.05.29.728167v1?rss=1&utm_source=dlvr.it&utm_medium=mastodon #BioRxiv #MassSpecRSS
- (RSS) (ACS Anal Chem) [ASAP] Reactive Paper Spray Mass Spectrometry Enables Speciation of Trace Levels of Mercuric Halides: Analytical ChemistryDOI: 10.1021/acs.analchem.6c02808 http://dx.doi.org/10.1021/acs.analchem.6c02808?utm_source=dlvr.it&utm_medium=mastodon #MassSpecRSS #ACSAChem
- (RSS) (BioRxiv All) Integrated multi-omics reveals adaptive anti-oxidant remodeling in early alcohol-associated liver disease: Alcohol-associated liver disease (ALD) is a leading cause of liver-related morbidity and mortality. Although various omics approaches have revealed early metabolic alterations, individual datasets provide limited mechanistic insight. Here, we integrated RNA sequencing with mass spectrometry-based analyses to quantify gene… https://www.biorxiv.org/content/10.64898/2026.05.28.728507v1?rss=1&utm_source=dlvr.it&utm_medium=mastodon #BioRxiv #MassSpecRSS
- (RSS) (BioRxiv All) SILAC-Site: A streamlined workflow for determining phosphopeptide stoichiometries: Mass spectrometry-based proteomics enables in-depth investigation of protein phosphorylation, quantifying tens of thousands of phosphosites per sample following phosphopeptide enrichment. However, critical information on phosphosite occupancy (stoichiometry) is typically lost during the phospho-enrichment process. Here, we introduce SILAC-Site, a… https://www.biorxiv.org/content/10.64898/2026.05.28.728441v1?rss=1&utm_source=dlvr.it&utm_medium=mastodon #BioRxiv #MassSpecRSS
- (RSS) (BioRxiv All) Nano- and microplastics in pediatric tonsil tissue: bioaccumulation, distribution, and immunomodulatory effects in human lymphoid aggregate organoids: Nano- and microplastics (NMPs), by-products of the fragmentation and degradation of plastic products, are ubiquitous environmental contaminants, yet their burden in pediatric immune tissues and functional consequences for developing immunity remain unknown. Here we report the first… https://www.biorxiv.org/content/10.64898/2026.05.27.728317v1?rss=1&utm_source=dlvr.it&utm_medium=mastodon #BioRxiv #MassSpecRSS
- (RSS) (BioRxiv All) A Charge Detection Mass Spectrometer for the Analysis of Megadalton-sized Molecules: Advances in Electrostatic Linear Ion Trap (ELIT) Charge Detection Mass Spectrometry (CDMS) over the past 10 years have revolutionized its use for analyzing very high-molecular-weight species such as protein complexes, viral vectors, vaccines, viruses, and amyloid fibrils. Nonetheless, ELIT-based CDMS has remained confined to a small number of… https://www.biorxiv.org/content/10.64898/2026.05.28.728353v1?rss=1&utm_source=dlvr.it&utm_medium=mastodon #BioRxiv #MassSpecRSS
- (RSS) (BioRxiv All) p38 dependent IL-33 responses define a conserved inflammatory programme in mast cells: Interleukin-33 (IL-33) is a key cytokine in mast cell mediated immunity, promoting inflammatory cytokine production without inducing degranulation. Here, we compared IL-33 induced proteomic responses across three mast cell culture systems, Foetal Liver derived Mast Cells (FLMCs), Bone Marrow derived Mast Cells (BMMCs), and Peritoneal Mast Cells… https://www.biorxiv.org/content/10.64898/2026.05.29.728623v1?rss=1&utm_source=dlvr.it&utm_medium=mastodon #BioRxiv #MassSpecRSS
- (RSS) (BioRxiv All) Antimicrobial activity of polymyxin A, and characterisation of the cognate biosynthetic gene cluster within the genome of the producing Paenibacillus polymyxa.: We report the isolation and identification of a Paenibacillus polymyxa strain from the citizen science project; Swab and Send. Through whole genome sequencing we are able to describe the biosynthetic gene cluster of polymyxin A produced by P. polymyxa 1G (NCBI accession… https://www.biorxiv.org/content/10.64898/2026.05.29.728749v1?rss=1&utm_source=dlvr.it&utm_medium=mastodon #BioRxiv #MassSpecRSS
