- (RSS) (J Sep Sci) Rapid and Sensitive Quantitation of Fipronil and Its Metabolites Fipronil Sulfone, Fipronil Sulfide, and Fipronil Desulfinyl in Zebrafish Tissues by UHPLC‐MS/MS: ABSTRACTAn ultra-high performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) method was developed and validated for the simultaneous determination of fipronil and its three metabolites (fipronil sulfone, fipronil sulfide, and fipronil desulfinyl) in… https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/jssc.70326?af=R&utm_source=dlvr.it&utm_medium=mastodon #JSepSci #MassSpecRSS
- (RSS) (BioRxiv All) Serum Lipidome as an Early Peripheral Indicator in Familial Alzheimers Disease: Protein biomarkers in biofluids are highly sensitive indicators of prodromal cognitive impairment yet remain limited for primary prevention. Lipids, essential to brain structure and function, offer untapped prognostic value. Here, we identify a lipidomic signature in serum from asymptomatic PSEN1-E280A mutation carriers aged 6-40 years, that… https://www.biorxiv.org/content/10.1101/2025.11.25.690392v1?rss=1&utm_source=dlvr.it&utm_medium=mastodon #BioRxiv #MassSpecRSS
- (RSS) (Biomed Chrom) Simultaneous Determination of Olmesartan and Hydrochlorothiazide in Human Plasma by UPLC–MS/MS Method and Its Application to a Bioequivalence Study: ABSTRACTA simple, sensitive and efficient ultra performance liquid chromatography–mass spectrometry (UPLC–MS/MS) method for simultaneous quantitative determination of olmesartan and hydrochlorothiazide in human plasma has been developed and validated. Using olmesartan-d4… https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/bmc.70254?af=R&utm_source=dlvr.it&utm_medium=mastodon #massSpecRSS #biomedchrom
- (RSS) (Biomed Chrom) A System Pharmacology Approach: Deciphering Atheroprotective Mechanisms of Yi‐Mai Compound Through Integrative Analysis of UPLC‐ESI‐MS Profiling, Network Targeting, and Molecular Docking: ABSTRACTYi-Mai compound (YMHJ), a traditional Chinese medicine formulation, has demonstrated therapeutic efficacy against atherosclerosis (AS) in clinical observational studies. To elucidate its underlying pharmacological mechanisms,… https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/bmc.70263?af=R&utm_source=dlvr.it&utm_medium=mastodon #massSpecRSS #biomedchrom
- (RSS) In-situ cross-linking mass spectrometry reveals compartment-specific proteasomal interactions and structural heterogeneity https://www.nature.com/articles/s41467-025-65752-6?utm_source=dlvr.it&utm_medium=mastodon #nature #MassSpecRSS
- (RSS) Structural mechanisms of allosteric regulation in the human cis-prenyltransferase complex https://www.nature.com/articles/s41467-025-65833-6?utm_source=dlvr.it&utm_medium=mastodon #nature #MassSpecRSS
- (RSS) (BioRxiv All) Host-derived lipid transfer and metabolic reprogramming in a ciliate-algal symbiosis: Symbiotic associations enable species to integrate complementary traits and adapt to novel environments. However, how the host and endosymbiont exchange nutrients remains poorly understood in most cases. Previously Paramecium bursaria cells were shown to reorganize lipid droplets to accommodate endosymbiotic Chlorella cells and interfering with… https://www.biorxiv.org/content/10.1101/2025.11.27.690892v1?rss=1&utm_source=dlvr.it&utm_medium=mastodon #BioRxiv #MassSpecRSS
- (RSS) (BioRxiv All) Structure of NO16, a marine non-tailed vibriophage with a global distribution: Non-tailed phages remain an underexplored group in marine environments, as tailed phages have dominated sequence and culture collections. However, recent surveys indicate that non-tailed phages might be more abundant than tailed phages, and with different effects on microbial mortality and gene transfer. Here, we report the structural characterization… https://www.biorxiv.org/content/10.1101/2025.11.28.690173v1?rss=1&utm_source=dlvr.it&utm_medium=mastodon #BioRxiv #MassSpecRSS
- (ACA) (ACA) MALDI Mass Spectrometry and Imaging for Lipid Analysis in Food Matrices: A Review of Analytical Principles and Perspectives: Publication date: Available online 28 November 2025Source: Analytica Chimica ActaAuthor(s): Ana Jano, Adrián Fuente-Ballesteros, M.Teresa Martín, Ana M. Ares, José Bernal https://www.sciencedirect.com/science/article/pii/S0003267025013285?dgcid=rss_sd_all&utm_source=dlvr.it&utm_medium=mastodon (RSS) #AChimActa #MassSpecRSS
- (ACA) (ACA) Differentiation of CBD and Δ9-THC isomers using copper-ion complexation and electrospray ionization-tandem mass spectrometry: Publication date: Available online 28 November 2025Source: Analytica Chimica ActaAuthor(s): Alleigh N. Couch, Christopher M. Zall, J.Tyler Davidson https://www.sciencedirect.com/science/article/pii/S0003267025013479?dgcid=rss_sd_all&utm_source=dlvr.it&utm_medium=mastodon (RSS) #AChimActa #MassSpecRSS
- (RSS) (BioRxiv All) Proteostasis Modelling using Deuterated Water Metabolic Labeling and Data-Independent Acquisition Mass Spectrometry: We present the first application of a deuterated water metabolic labeling workflow coupled with data-independent acquisition (DIA) tandem mass spectrometry (MS/MS) for quantifying label enrichment in MS/MS to study protein turnover. The approach automates the turnover rate determination from combined precursor and… https://www.biorxiv.org/content/10.1101/2025.11.25.690247v1?rss=1&utm_source=dlvr.it&utm_medium=mastodon #BioRxiv #MassSpecRSS
- (RSS) (J Proteom) Opt-TMT: An optimized and scaled-down TMT labeling strategy for limited sample: Publication date: Available online 27 November 2025Source: Journal of ProteomicsAuthor(s): Michele Martins, Fábio César Sousa Nogueira, Magno Junqueira, Guillaume Nugue https://www.sciencedirect.com/science/article/pii/S1874391925002039?dgcid=rss_sd_all&utm_source=dlvr.it&utm_medium=mastodon #MassSpecRSS
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