BioRxiv
bioRxiv Subject Collection: Systems Biology
This feed contains articles for bioRxiv Subject Collection "Systems Biology"
A compact model for cold tolerance entrainment based on the ICE1-CBF-COR pathway in plants
Most temperate plants can tolerate both chilling and freezing temperatures. Plants have developed self-defense mechanisms to perceive cold signal, trigger the cold tolerance for the cold response ICE1-CBF-COR pathway by packing a cascade of kinase phosphorylation/dephosphorylation events into a functional module. Linked to the central ICE1-CBF-COR model, two sub-models were adopted for the second messenger Ca2+ — a one-compartment model for Ca2+ transient and a two-compartment model for a train of Ca2+ spikes. Numerical simulation verified the expression patterns of the cold-induced genes as observed in Arabidopsis thaliana, Brassica napa and Solanum lycopersicum, including wild types and mutants. Moreover, the desensitization and resensitization of CBF3 and COR15A were displayed as well as the dynamics in the gradually decreasing temperature response to cold stress. The duration of cold tolerance was predicted for approximate 10 days. Interpreting and predicting the dynamical behaviors of the cold signaling pathway are valuable and time-saving for understanding mechanisms of cold acclimation.
Huang, T., Wu, Y., Lv, H., Shu, Y., Yu, L., Yang, H., Hou, X., You, X.
February 25, 2023
http://biorxiv.org/cgi/content/short/2023.02.23.529825v1?rss=1