{"id":2668,"date":"2002-03-29T17:27:43","date_gmt":"2002-03-29T23:27:43","guid":{"rendered":"https:\/\/kermitmurray.com\/murray\/?p=2668"},"modified":"2019-08-29T17:29:52","modified_gmt":"2019-08-29T22:29:52","slug":"ir-ldi-on-silicon","status":"publish","type":"post","link":"https:\/\/kermitmurray.com\/research\/2002\/03\/ir-ldi-on-silicon\/","title":{"rendered":"Infrared laser desorption\/ionization on silicon"},"content":{"rendered":"\n<div class=\"wp-block-caxton-grid relative\"><div class=\"absolute absolute--fill\"><div class=\"cover bg-center absolute absolute--fill\" style=\"background-color:;background-image:linear-gradient( );\"><\/div><div class=\"absolute absolute--fill\" style=\"background-color:;background-image:linear-gradient( );opacity:1;\"><\/div><\/div><div class=\"relative caxton-columns caxton-grid-block\" style=\"padding-top:0;padding-left:0;padding-bottom:0;padding-right:0;grid-template-columns:repeat(12, 1fr)\" data-tablet-css=\"padding-left:em;padding-right:em;\" data-mobile-css=\"padding-left:em;padding-right:em;\">\n<div class=\"wp-block-caxton-section relative\" style=\"grid-area:span 1\/span 12\"><div class=\"absolute absolute--fill\"><div class=\"cover bg-center absolute absolute--fill\" style=\"background-color:;background-image:linear-gradient( );\"><\/div><div class=\"absolute absolute--fill\" style=\"background-color:;background-image:linear-gradient( );opacity:1;\"><\/div><\/div><div class=\"relative caxton-section-block\" style=\"padding-top:5px;padding-left:5px;padding-bottom:5px;padding-right:5px\" data-mobile-css=\"padding-left:1em;padding-right:1em;\" data-tablet-css=\"padding-left:1em;padding-right:1em;\">\n<p>S.H. Bhattacharya, T.J. Raiford, K.K. Murray, &#8220;Infrared laser desorption\/ionization on silicon,&#8221; <em>Anal. Chem.<\/em><strong>74<\/strong> (2002) 2228\u20132231. doi:<a href=\"http:\/\/doi.org\/10.1021\/ac0112972\">10.1021\/ac0112972<\/a>.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Abstract<\/h4>\n\n\n\n<div class=\"wp-block-image\"><figure class=\"alignright is-resized\"><a href=\"https:\/\/kermitmurray.com\/murray\/?attachment_id=2671\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/kermitmurray.com\/murray\/wp-content\/uploads\/2019\/08\/IR-DIOS-Figure-1-806x1024.jpg\" alt=\"LDI MS of bradykinin at 2.94 \u00b5m from (a) silicon and (b) stainless steel targets\" class=\"wp-image-2671\" width=\"605\" height=\"768\" srcset=\"https:\/\/kermitmurray.com\/research\/wp-content\/uploads\/2019\/08\/IR-DIOS-Figure-1-806x1024.jpg 806w, https:\/\/kermitmurray.com\/research\/wp-content\/uploads\/2019\/08\/IR-DIOS-Figure-1-236x300.jpg 236w, https:\/\/kermitmurray.com\/research\/wp-content\/uploads\/2019\/08\/IR-DIOS-Figure-1-768x975.jpg 768w, https:\/\/kermitmurray.com\/research\/wp-content\/uploads\/2019\/08\/IR-DIOS-Figure-1.jpg 1200w\" sizes=\"auto, (max-width: 605px) 100vw, 605px\" \/><\/a><figcaption>Laser desorption\/ionization mass spectra of bradykinin at 2.94 \u00b5m from (a) silicon and (b) stainless steel targets.<\/figcaption><\/figure><\/div>\n\n\n\n<p>Laser desorption\/ionization from a single-crystal silicon surface was performed using a laser operating in the 3-\u03bcm region of the mid-infrared. Analyte molecules up to 6 kDa were ionized with no added matrix. As with ultraviolet desorption\/ionization from porous silicon (DIOS), IR laser desorption from silicon does not produce matrix ions that can interfere with analysis of low-mass analytes. However, in contrast to UV DIOS, silicon porosity or roughness is not required for ionization using an IR laser. Mass spectra were obtained in the wavelength range between 2.8 and 3.5 \u03bcm, which is consistent with energy absorption by a hydrogen-bonded OH group. A mechanism based on desorption of adsorbed solvent molecules is postulated.<\/p>\n<\/div><\/div>\n<\/div><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":2671,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[134,5],"tags":[8,9],"class_list":["post-2668","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-lsu","category-publication","tag-infrared","tag-maldi","entry"],"_links":{"self":[{"href":"https:\/\/kermitmurray.com\/research\/wp-json\/wp\/v2\/posts\/2668","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/kermitmurray.com\/research\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/kermitmurray.com\/research\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/kermitmurray.com\/research\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/kermitmurray.com\/research\/wp-json\/wp\/v2\/comments?post=2668"}],"version-history":[{"count":3,"href":"https:\/\/kermitmurray.com\/research\/wp-json\/wp\/v2\/posts\/2668\/revisions"}],"predecessor-version":[{"id":2673,"href":"https:\/\/kermitmurray.com\/research\/wp-json\/wp\/v2\/posts\/2668\/revisions\/2673"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/kermitmurray.com\/research\/wp-json\/wp\/v2\/media\/2671"}],"wp:attachment":[{"href":"https:\/\/kermitmurray.com\/research\/wp-json\/wp\/v2\/media?parent=2668"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/kermitmurray.com\/research\/wp-json\/wp\/v2\/categories?post=2668"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/kermitmurray.com\/research\/wp-json\/wp\/v2\/tags?post=2668"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}