{"id":2284,"date":"2012-09-02T13:29:24","date_gmt":"2012-09-02T18:29:24","guid":{"rendered":"https:\/\/kermitmurray.com\/murray\/?p=2284"},"modified":"2019-08-03T16:11:16","modified_gmt":"2019-08-03T21:11:16","slug":"ir-laser-ablation-sample-transfer-for-on-line-lc-esi-ms","status":"publish","type":"post","link":"https:\/\/kermitmurray.com\/research\/2012\/09\/ir-laser-ablation-sample-transfer-for-on-line-lc-esi-ms\/","title":{"rendered":"Infrared laser ablation sample transfer for on-line liquid chromatography electrospray ionization mass spectrometry"},"content":{"rendered":"\n<div class=\"wp-block-caxton-grid relative\"><div class=\"absolute absolute--fill\"><div class=\"cover bg-center absolute absolute--fill\" style=\"background-color:;background-image:linear-gradient( );\"><\/div><div class=\"absolute absolute--fill\" style=\"background-color:;background-image:linear-gradient( );opacity:1;\"><\/div><\/div><div class=\"relative caxton-columns caxton-grid-block\" style=\"padding-top:0;padding-left:0;padding-bottom:0;padding-right:0;grid-template-columns:repeat(12, 1fr)\" data-tablet-css=\"padding-left:em;padding-right:em;\" data-mobile-css=\"padding-left:em;padding-right:em;\">\n<div class=\"wp-block-caxton-section relative\" style=\"grid-area:span 1\/span 12\"><div class=\"absolute absolute--fill\"><div class=\"cover bg-center absolute absolute--fill\" style=\"background-color:;background-image:linear-gradient( );\"><\/div><div class=\"absolute absolute--fill\" style=\"background-color:;background-image:linear-gradient( );opacity:1;\"><\/div><\/div><div class=\"relative caxton-section-block\" style=\"padding-top:5px;padding-left:5px;padding-bottom:5px;padding-right:5px\" data-mobile-css=\"padding-left:1em;padding-right:1em;\" data-tablet-css=\"padding-left:1em;padding-right:1em;\">\n<p>S.-G. Park, K.K. Murray, &#8220;Infrared laser ablation sample transfer for on-line liquid chromatography electrospray ionization mass spectrometry,&#8221; <em>J. Mass Spectrom.<\/em> <strong>47<\/strong> (2012) 1322\u20131326. doi:<a href=\"http:\/\/doi.org\/10.1002\/jms.3096\">10.1002\/jms.3096<\/a>.<\/p>\n\n\n\n<h5 class=\"wp-block-heading\">Abstract<\/h5>\n\n\n\n<div class=\"wp-block-image\"><figure class=\"alignright is-resized\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/kermitmurray.com\/murray\/wp-content\/uploads\/2019\/08\/Park-2012-Fig-1-300x155.jpg\" alt=\"Schematic of the laser ablation sample transfer collection system for on\u2010line ESI\" class=\"wp-image-2286\" width=\"300\" height=\"155\" srcset=\"https:\/\/kermitmurray.com\/research\/wp-content\/uploads\/2019\/08\/Park-2012-Fig-1-300x155.jpg 300w, https:\/\/kermitmurray.com\/research\/wp-content\/uploads\/2019\/08\/Park-2012-Fig-1-768x396.jpg 768w, https:\/\/kermitmurray.com\/research\/wp-content\/uploads\/2019\/08\/Park-2012-Fig-1.jpg 876w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><figcaption>Schematic of the laser ablation sample transfer collection system for on\u2010line electrospray ionization.<\/figcaption><\/figure><\/div>\n\n\n\n<p>We have demonstrated an on-line laser ablation sampling system and coupling of the system to liquid chromatography (LC) using an infrared (IR) laser to ablate and transfer materials into a flowing solvent stream. With this approach, samples are deposited on a microscope slide mounted on a translation stage and ablated in transmission geometry using a pulsed mid-IR laser. The ablated material is captured in an exposed flowing solvent stream that carries the ablated material to the electrospray source. Post-ablation separation is accomplished using a capillary column downstream of the capture zone. The performance of the system was assessed using peptide and protein mixtures ablated from the target and analyzed with and without LC separation. <\/p>\n<\/div><\/div>\n<\/div><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[79,134,5],"tags":[117,8,116,135,77],"class_list":["post-2284","post","type-post","status-publish","format-standard","hentry","category-last","category-lsu","category-publication","tag-electrospray","tag-infrared","tag-liquid-chromatography","tag-lsu","tag-publication","entry"],"_links":{"self":[{"href":"https:\/\/kermitmurray.com\/research\/wp-json\/wp\/v2\/posts\/2284","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/kermitmurray.com\/research\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/kermitmurray.com\/research\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/kermitmurray.com\/research\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/kermitmurray.com\/research\/wp-json\/wp\/v2\/comments?post=2284"}],"version-history":[{"count":5,"href":"https:\/\/kermitmurray.com\/research\/wp-json\/wp\/v2\/posts\/2284\/revisions"}],"predecessor-version":[{"id":2290,"href":"https:\/\/kermitmurray.com\/research\/wp-json\/wp\/v2\/posts\/2284\/revisions\/2290"}],"wp:attachment":[{"href":"https:\/\/kermitmurray.com\/research\/wp-json\/wp\/v2\/media?parent=2284"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/kermitmurray.com\/research\/wp-json\/wp\/v2\/categories?post=2284"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/kermitmurray.com\/research\/wp-json\/wp\/v2\/tags?post=2284"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}