{"id":2195,"date":"1993-05-25T14:47:50","date_gmt":"1993-05-25T19:47:50","guid":{"rendered":"https:\/\/kermitmurray.com\/murray\/?p=2195"},"modified":"2024-02-20T09:39:00","modified_gmt":"2024-02-20T15:39:00","slug":"aerosol-maldi","status":"publish","type":"post","link":"https:\/\/kermitmurray.com\/research\/1993\/05\/aerosol-maldi\/","title":{"rendered":"Aerosol Matrix-Assisted Laser-Desorption Ionization Mass-Spectrometry"},"content":{"rendered":"\n
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K.K. Murray, D.H. Russell, “Aerosol Matrix-Assisted Laser-Desorption Ionization Mass-Spectrometry, “ J. Am. Soc. Mass Spectrom<\/em>. 5<\/strong> (1994) 1\u20139. doi:10.1016\/1044-0305(94)85077-1<\/a>.<\/p>\n<\/div><\/div>\n<\/div><\/div>\n\n\n\n

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Abstract: <\/em>A new method of liquid sample introduction for a time-of-flight mass spectrometer (TOF-MS) has been developed by applying the method of matrix-assisted laser desorption ionization to aerosols. Analyte biomolecules are dissolved in a methanol solvent along with a UVabsorbing matrix and formed into an aerosol with a pneumatic nebulizer. The aerosol particles are dried in a heated skimmer tube before ionization by pulsed 355-nm UV laser radiation. Mass analysis is achieved in a linear TOF-MS. Results for the ionization of bovine insulin (5733.5 Mw) are reported.<\/p>\n<\/div><\/div>\n\n\n\n

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Aerosol MALDI apparatus at Texas A&M University<\/figcaption><\/figure>\n<\/div><\/div>\n<\/div><\/div>\n\n\n\n
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\"AMALDI
Texas A&M Aerosol MALDI instrument side view<\/figcaption><\/figure>\n<\/div><\/div>\n\n\n\n
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\"TAMU
Aerosol MALDI instrument at Texas A&M University, showing the flight tube (right) and ion source (left).<\/figcaption><\/figure>\n<\/div><\/div>\n<\/div><\/div>\n\n\n\n
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\"TAMU
Roots blower and backing pump at Texas A&M University, 1992<\/figcaption><\/figure>\n<\/div><\/div>\n\n\n\n
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\"AMALDI
Aerosol MALDI Instrument at Texas A&M University, 1992.<\/figcaption><\/figure>\n\n\n\n
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Kermit Murray at Texas A&M University in 1993<\/figcaption><\/figure>\n<\/div><\/div>\n<\/div><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":965,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[143,17,5,133],"tags":[104,11,9],"class_list":["post-2195","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-aerosol","category-instrum","category-publication","category-tamu","tag-aerosol","tag-asms","tag-maldi","entry"],"_links":{"self":[{"href":"https:\/\/kermitmurray.com\/research\/wp-json\/wp\/v2\/posts\/2195","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/kermitmurray.com\/research\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/kermitmurray.com\/research\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/kermitmurray.com\/research\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/kermitmurray.com\/research\/wp-json\/wp\/v2\/comments?post=2195"}],"version-history":[{"count":3,"href":"https:\/\/kermitmurray.com\/research\/wp-json\/wp\/v2\/posts\/2195\/revisions"}],"predecessor-version":[{"id":2198,"href":"https:\/\/kermitmurray.com\/research\/wp-json\/wp\/v2\/posts\/2195\/revisions\/2198"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/kermitmurray.com\/research\/wp-json\/wp\/v2\/media\/965"}],"wp:attachment":[{"href":"https:\/\/kermitmurray.com\/research\/wp-json\/wp\/v2\/media?parent=2195"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/kermitmurray.com\/research\/wp-json\/wp\/v2\/categories?post=2195"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/kermitmurray.com\/research\/wp-json\/wp\/v2\/tags?post=2195"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}