ASMS 2024: Deep Ultraviolet and Infrared Laser Ablation of Carbonic Anhydrase II

Deep Ultraviolet and Infrared Laser Ablation of Carbonic Anhydrase II Neda Feizi1; Kadeem O Hayes2; Blessing Chisom Egbejiogu2; Kelcey B. Hines2; Kermit K. Murray2; Touradj Solouki11Baylor University, Waco, TX; 2Louisiana State University, Baton Rouge, LA IntroductionIntegrating ion mobility-mass spectrometry (IM-MS) with laser ablation (LA) holds great appeal for acquiring spatially resolved details on protein conformations. …

Infrared Matrix Assisted Laser Desorption Ionization Mass Spectrometry II

National Science Foundation Infrared Matrix Assisted Laser Desorption Ionization Mass Spectrometry Abstract Professor Kermit Murray of Louisiana State University is supported by the Analytical and Surface Chemistry Program to further the development and application of infrared matrix-assisted laser desorption ionization mass spectrometry (IR-MALDI). IR-MALDI is not as widely accepted a method as MALDI using ultraviolet …

Infrared Matrix-assisted Laser Desorption Ionization Mass Spectrometry I

National Science Foundation Infrared Matrix-assisted Laser Desorption/Ionization Mass Spectrometry Abstract This award to Professor Kermit Murray of Emory University entitled “Infrared Matrix-assisted Laser Desorption/Ionization Mass Spectrometry (IR-MALDI)” is supported by the Analytical and Surface Chemistry Program. The goals of the research are to address fundamental problems in the understanding of IR-MALDI. The research will study …

Infrared Laser Desorption Mass Spectrometry

National Science Foundation Infrared Laser Desorption Mass Spectrometry Abstract The Analytical and Surface Chemistry Program supports Prof. Kermit Murray of Louisiana State University for research targeting enhanced understanding and extended application of laser desorption ionization mass spectrometry. Specific aims are to i) probe particle generation during infrared (IR) laser desorption, ii) develop IR laser desorption …

Infrared Laser Ambient Mass Spectrometry

National Science Foundation Infrared Laser Ambient Mass Spectrometry Abstract With support from the Chemical Measurement and Imaging Program in the Division of Chemistry, Professor Murray and his group at Louisiana State University and Agricultural and Mechanical College in Baton Rouge will develop new instrumentation for rapid chemical and biochemical analysis under ambient conditions. The instruments …

Infrared Laser Ablation Microsampling for Mass Spectrometry Imaging

National Science Foundation Infrared Laser Ablation Microsampling for Mass Spectrometry Imaging Abstract This project is funded by the Chemical Measurement and Imaging program of the Chemistry Division. Professors Kermit Murray of Louisiana State University (LSU) and Professor Touradj Solouki of Baylor University are developing techniques for looking at (imaging) biological tissue in order to identify …

Infrared Laser Desorption Ion Mobility Mass Spectrometer (Phase II)

National Institutes of Health Infrared Laser Desorption Ion Mobility Mass Spectrometer Abstract The development of an infrared laser desorption ionization ion mobility mass spectrometer (IR LDI IM MS) will be continued. The analysis of test biomolecules such as peptides and proteins in the Phase I of the project has demonstrated that the new system’s performance …

Infrared Laser Desorption Ion Mobility Mass Spectrometer (Phase I)

National Institutes of Health Infrared Laser Desorption Ion Mobility Mass Spectrometer Abstract The goal of this [SBIR Phase I] research program is to develop an infrared laser desorption ionization (IR-LDI) ion mobility mass spectrometer (IMMS) for application to the analysis of biomolecules in complex systems such as direct tissue studies and the identification of the …

A Compact Turnable Infrared Laser for MALDI MS (Phase II)

National Institutes of Health A Compact Turnable Infrared Laser for MALDI MS Abstract The goal of this Phase II STTR cooperative research program between OPOTEK and Emory University is to continue development of a small and inexpensive infrared laser based on optical parametric oscillator (OPO) technology and to develop a target system specifically designed for …

A Compact Turnable Infrared Laser for MALDI MS (Phase I)

National Institutes of Health A Compact Turnable Infrared Laser for MALDI MS Abstract The goal of the proposed [SBIR Phase I] research is to develop compact, inexpensive, and tunable infrared (IR) laser for use with matrix-assisted laser desorption ionization (MALDI) mass spectrometry. MALDI is a powerful tool for the analysis of large biological molecules and …