Middle-down proteomics
From Mass Spec Terms
(Redirected from Middle-down mass spectrometry)
| DRAFT DEFINITION |
| Middle-down proteomics |
|---|
| Top-down proteomics applied to a protein that has been cleaved into a few large fragments. |
| Related Term(s): bottom-up proteomics, middle-up proteomics |
| Reference(s): |
| This is an unofficial draft definition presented for information and comment. |
External links
- http://dx.doi.org/10.1007/s13361-019-02201-x F. Lermyte, Y.O. Tsybin, P.B. O'Connor, J.A. Loo, Top or Middle? Up or Down? Toward a Standard Lexicon for Protein Top-Down and Allied Mass Spectrometry Approaches, J Am Soc Mass Spectrom (2019)
- http://dx.doi.org/10.1021/pr800635m Tandem Mass Spectrometry with Ultrahigh Mass Accuracy Clarifies Peptide Identification by Database Retrieval, Michael T. Boyne II, Benjamin A. Garcia, Mingxi Li, Leonid Zamdborg, Craig D. Wenger, Shannee Babai, and Neil L. Kelleher, Journal of Proteome Research 2009 8 (1), 374-379
