Gas chromatography-mass spectrometry: Difference between revisions

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gas chromatography/mass spectrometry (GC/MS)
|def=
'''gas chromatography-mass spectrometry (GC-MS)'''


gas chromatography-mass spectrometry
'''gas chromatography/mass spectrometry (GC/MS)'''
Technique by which a mixture is separated into individual components by gas chromatography, followed by detection with a [[mass spectrometer]].


The technique by which a mixture of analytes is separated into individual components by gas chromatography, followed by the ionization of the separation effluent in the ion source of a mass spectrometer.
:''Note 1'': Either a hyphen or slash can be used to indicate combined instruments.


Note: There is no consensus on the use of a slash or hyphen in this term.
:''Note 2'': The [[mass spectrum]] is typically obtained on a time scale that allows resolution of the component in a single chromatographic peak.


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|rel=[[liquid chromatography-mass spectrometry]] (LC-MS), [[supercritical fluid chromatography-mass spectrometry]] (SFC-MS), [[thin layer chromatography-mass spectrometry]] (TLC-MS).
#J. Lederberg, M. Wightman. Anal. Chem. 36, 2362-2363 (1964).
|ref=J. Lederberg, M. Wightman. Anal. Chem. 36, 2362 (1964). (http://dx.doi.org/10.1021/ac60218a047 )
#R. S. Gohlke, F. W. McLafferty. J. Am. Soc. Mass Spectrom. 4, 367-371 (1993).


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R. S. Gohlke, F. W. McLafferty. J. Am. Soc. Mass Spectrom. 4, 367 (1993). (http://dx.doi.org/10.1016/1044-0305(93)85001-E ) 


{{jchrom|
A combined technique in which a mixture of analytes is separated into individual components by gas chromatography, followed by the ionization of the separated compounds in the[[ ion source]] of a [[mass spectrometer]]. The hyphenated form gas chromatography-mass spectrometry is used interchangeably.
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#J. Lederberg, M. Wightman, Anal. Chem. 36 (1964) 2362.
#R.S. Gohlke, F.W. McLafferty, J. Am. Soc. Mass Spectrom. 4 (1993) 367.
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{{asms|
==Abbreviations of combined methods - the "slashes and hyphens" issue==
combined technique for mixture analysis in which the separated GC components are passed continuously into the MS.
{{quote|quote=
The hyphen, or alternatively the slash (forward stroke), can be used to indicate combined methods such as gas chromatography separation combined for example, gas-liquid chromatography and pyrolysis-gas chromatography [6]. The authors of this document are evenly split in their preference for hyphen or slash. For consistency with the prior recommendations, we use the hyphen for combined techniques but note that the slash can be used inter- changeably.
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== External links ==
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Revision as of 18:16, 22 October 2013