{"id":2733,"date":"2022-12-25T08:17:16","date_gmt":"2022-12-25T14:17:16","guid":{"rendered":"https:\/\/kermitmurray.com\/msblog\/?page_id=2733"},"modified":"2022-12-25T09:55:44","modified_gmt":"2022-12-25T15:55:44","slug":"reddit-r-analyticalchemistry","status":"publish","type":"page","link":"https:\/\/kermitmurray.com\/msblog\/links\/social-feeds\/reddit-feeds\/reddit-r-analyticalchemistry\/","title":{"rendered":"Reddit r\/analyticalchemistry"},"content":{"rendered":"\n<div class=\"wp-block-caxton-grid relative\"><div class=\"absolute absolute--fill\"><div class=\"absolute absolute--fill cover bg-center\" style=\"background-color:;background-image:linear-gradient( );\"><\/div><div class=\"absolute absolute--fill\" style=\"background-color:;background-image:linear-gradient( );opacity:1;\"><\/div><\/div><div class=\"relative caxton-columns caxton-grid-block\" style=\"padding-top:0;padding-left:0;padding-bottom:0;padding-right:0;grid-template-columns:repeat(12, 1fr)\" data-tablet-css=\"padding-left:em;padding-right:em;\" data-mobile-css=\"padding-left:em;padding-right:em;\">\n<div class=\"wp-block-caxton-section relative\" style=\"grid-area:span 1\/span 8\"><div class=\"absolute absolute--fill\"><div class=\"absolute absolute--fill cover bg-center\" style=\"background-color:;background-image:linear-gradient( );\"><\/div><div class=\"absolute absolute--fill\" style=\"background-color:;background-image:linear-gradient( );opacity:1;\"><\/div><\/div><div class=\"relative caxton-section-block\" style=\"padding-top:5px;padding-left:5px;padding-bottom:5px;padding-right:5px\" data-mobile-css=\"padding-left:1em;padding-right:1em;\" data-tablet-css=\"padding-left:1em;padding-right:1em;\">\n<p><a href=\"https:\/\/www.reddit.com\/r\/analyticalchemistry\/\" target=\"_blank\" rel=\"noreferrer noopener\"><strong>\/r\/analyticalchemistry\/<\/strong><\/a><\/p>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-caxton-section relative\" style=\"grid-area:span 1\/span 4\"><div class=\"absolute absolute--fill\"><div class=\"absolute absolute--fill cover bg-center\" style=\"background-color:;background-image:linear-gradient( );\"><\/div><div class=\"absolute absolute--fill\" style=\"background-color:;background-image:linear-gradient( );opacity:1;\"><\/div><\/div><div class=\"relative caxton-section-block\" style=\"padding-top:5px;padding-left:5px;padding-bottom:5px;padding-right:5px\" data-mobile-css=\"padding-left:1em;padding-right:1em;\" data-tablet-css=\"padding-left:1em;padding-right:1em;\">\n<p><strong><a href=\"https:\/\/www.reddit.com\/r\/analyticalchemistry.rss\" target=\"_blank\" rel=\"noreferrer noopener\">RSS<\/a><\/strong><\/p>\n<\/div><\/div>\n<\/div><\/div>\n\n\n<ul class=\"has-dates has-authors has-excerpts wp-block-rss\"><li class='wp-block-rss__item'><div class='wp-block-rss__item-title'><a href='https:\/\/www.reddit.com\/r\/analyticalchemistry\/comments\/1tab6rh\/any_help_with_mass_specs_with_lab_setup_to_data\/'>Any help with mass specs with lab setup to data processing<\/a><\/div><time datetime=\"2026-05-11T18:02:45-05:00\" class=\"wp-block-rss__item-publish-date\">May 11, 2026<\/time> <span class=\"wp-block-rss__item-author\">by \/u\/PFAS123<\/span><div class=\"wp-block-rss__item-excerpt\">Hello guys, If you are in California (San Diego, Orange County or SF Bay Area) and looking for someone\u2019s help to explore mass specs, set up a lab or want to troubleshoot the mass spec problem, please reach out to me and my team. I provide high level consulting work and also solutions to your need in the fraction of the price that you pay from Big Dawgs. From small molecules to Biopharma to Proteins, I have more than 8+ years of experience and my team members have experience more than 30+ years in mass spec. If there is a [&hellip;]<\/div><\/li><li class='wp-block-rss__item'><div class='wp-block-rss__item-title'><a href='https:\/\/www.reddit.com\/r\/analyticalchemistry\/comments\/1t9z4c0\/lgc_chemicals_trc_logical_reliability\/'>LGC Chemicals (TRC, LoGiCal, &#8230;) Reliability<\/a><\/div><time datetime=\"2026-05-11T10:21:16-05:00\" class=\"wp-block-rss__item-publish-date\">May 11, 2026<\/time> <span class=\"wp-block-rss__item-author\">by \/u\/formanz<\/span><div class=\"wp-block-rss__item-excerpt\">Hi everyone, we would like to buy some standards of synthetic cannabinoids and NSOs, but Cayman is quite expensive for us (at least for now). Do anyone have experience with LGC Chemicals distributor and brands like TRC or LoGiCal (sold by LGC)? Any comments will be appreciated, thank you! Have a nice day! submitted by \/u\/formanz [link] [comments]<\/div><\/li><li class='wp-block-rss__item'><div class='wp-block-rss__item-title'><a href='https:\/\/www.reddit.com\/r\/analyticalchemistry\/comments\/1t6g8yi\/need_help_with_quantitative_analysis\/'>Need help with quantitative Analysis<\/a><\/div><time datetime=\"2026-05-07T16:51:06-05:00\" class=\"wp-block-rss__item-publish-date\">May 7, 2026<\/time> <span class=\"wp-block-rss__item-author\">by \/u\/Heiduk00<\/span><div class=\"wp-block-rss__item-excerpt\">submitted by \/u\/Heiduk00 [link] [comments]<\/div><\/li><li class='wp-block-rss__item'><div class='wp-block-rss__item-title'><a href='https:\/\/www.reddit.com\/r\/analyticalchemistry\/comments\/1t5edut\/edtafe_complex_in_the_stability_of_ascorbic_acid\/'>EDTA-Fe complex in the stability of ascorbic acid<\/a><\/div><time datetime=\"2026-05-06T14:21:39-05:00\" class=\"wp-block-rss__item-publish-date\">May 6, 2026<\/time> <span class=\"wp-block-rss__item-author\">by \/u\/ForwardDaikon6761<\/span><div class=\"wp-block-rss__item-excerpt\">Hi, I have a question about the stability of ascorbic acid in a 0.1% H3PO4 solution. The solution has a concentration of 0.02 mg\/mL. Over the course of a few hours, the ascorbate peak drops (RSD% = 3%). If I add an EDTA-Fe complex to the standard solution, the degradation stops or at least decreases dramatically. However, I&#039;m not clear on the mechanism. Could someone explain it to me? submitted by \/u\/ForwardDaikon6761 [link] [comments]<\/div><\/li><li class='wp-block-rss__item'><div class='wp-block-rss__item-title'><a href='https:\/\/www.reddit.com\/r\/analyticalchemistry\/comments\/1t4x579\/stubborn_peak_coeluting_with_api_in_spraydried\/'>Stubborn peak co-eluting with API in spray-dried formulation (HPMCAS?) \u2014 column fouling or something else?<\/a><\/div><time datetime=\"2026-05-06T00:16:39-05:00\" class=\"wp-block-rss__item-publish-date\">May 6, 2026<\/time> <span class=\"wp-block-rss__item-author\">by \/u\/CommunityFrosty<\/span><div class=\"wp-block-rss__item-excerpt\">Hey everyone \u2014 looking for some advice on a column fouling issue. I\u2019m running an RP-HPLC assay on an Ascentis Express C18 (15 cm \u00d7 4.6 mm) for an API (MK-8507) that\u2019s spray-dried in HPMCAS. Mobile phase is 0.1% orthophosphoric acid (A) and ACN (B) with a ~29 min gradient. I keep getting a persistent interference peak right at ~13 min \u2014 basically co-eluting with my API. Full spectra matches closely, and the peak sticks around no matter what I do. I\u2019ve already tried flushing the column (forward flow) with: &#8211; ACN &#8211; IPA &#8211; Acetone None of that removed [&hellip;]<\/div><\/li><li class='wp-block-rss__item'><div class='wp-block-rss__item-title'><a href='https:\/\/www.reddit.com\/r\/analyticalchemistry\/comments\/1t0p5fb\/hplc_column_efficiency_and_resolution\/'>HPLC column efficiency and resolution<\/a><\/div><time datetime=\"2026-05-01T10:06:55-05:00\" class=\"wp-block-rss__item-publish-date\">May 1, 2026<\/time> <span class=\"wp-block-rss__item-author\">by \/u\/peniabipole<\/span><div class=\"wp-block-rss__item-excerpt\">I want to calculate HPLC column efficiency and resolution based on the our lab experimental results, but I\u2019m not sure which data I should use. We have 5 different standards and 1 sample, and for each standard there are 3 measurements. For example, if I choose the 1st standard (the lowest concentration), should I use the average of the 3 measurements or ? Also, which standard should I use for best? submitted by \/u\/peniabipole [link] [comments]<\/div><\/li><li class='wp-block-rss__item'><div class='wp-block-rss__item-title'><a href='https:\/\/www.reddit.com\/r\/analyticalchemistry\/comments\/1syu72y\/acidbased_des_vs_conventional_solvents_any\/'>Acid-based DES vs conventional solvents : any practical experience?<\/a><\/div><time datetime=\"2026-04-29T09:52:05-05:00\" class=\"wp-block-rss__item-publish-date\">April 29, 2026<\/time> <span class=\"wp-block-rss__item-author\">by \/u\/Apacukafundaluka12<\/span><div class=\"wp-block-rss__item-excerpt\">Hi everyone, I\u2019m currently experimenting with deep eutectic solvents (DES), mainly acid-based systems where one of the components is an organic acid. So far, I haven\u2019t had much success..in most cases, simple solvents like methanol or ethanol seem to outperform my DES mixtures in terms of extraction efficiency. I\u2019ve been working primarily with wood samples, but I\u2019m considering switching to other plant matrices to see if the results improve. Does anyone here have experience with DES in similar applications? I\u2019d really appreciate hearing about your insights, tips, or even negative results. anything that could help me better understand what I [&hellip;]<\/div><\/li><li class='wp-block-rss__item'><div class='wp-block-rss__item-title'><a href='https:\/\/www.reddit.com\/r\/analyticalchemistry\/comments\/1sytnyb\/frit_inversion_of_hplc\/'>Frit inversion of HPLC<\/a><\/div><time datetime=\"2026-04-29T09:20:59-05:00\" class=\"wp-block-rss__item-publish-date\">April 29, 2026<\/time> <span class=\"wp-block-rss__item-author\">by \/u\/ForwardDaikon6761<\/span><div class=\"wp-block-rss__item-excerpt\">Hi, is it possible to invert the input frit of an HPLC column with the output frit? submitted by \/u\/ForwardDaikon6761 [link] [comments]<\/div><\/li><li class='wp-block-rss__item'><div class='wp-block-rss__item-title'><a href='https:\/\/www.reddit.com\/r\/analyticalchemistry\/comments\/1sx2okb\/fluctuating_pressuresin_hplc_and_loss_of\/'>Fluctuating pressuresin HPLC and loss of resolution in HPLC<\/a><\/div><time datetime=\"2026-04-27T12:48:33-05:00\" class=\"wp-block-rss__item-publish-date\">April 27, 2026<\/time> <span class=\"wp-block-rss__item-author\">by \/u\/ForwardDaikon6761<\/span><div class=\"wp-block-rss__item-excerpt\">submitted by \/u\/ForwardDaikon6761 [link] [comments]<\/div><\/li><li class='wp-block-rss__item'><div class='wp-block-rss__item-title'><a href='https:\/\/www.reddit.com\/r\/analyticalchemistry\/comments\/1spuyal\/guesses_on_the_6545xts_remaining_lifecycle\/'>Guesses on the 6545XT&#039;s remaining lifecycle?<\/a><\/div><time datetime=\"2026-04-19T14:47:03-05:00\" class=\"wp-block-rss__item-publish-date\">April 19, 2026<\/time> <span class=\"wp-block-rss__item-author\">by \/u\/TheProudCanadian<\/span><div class=\"wp-block-rss__item-excerpt\">I have been pitching an investment in a hi-res LCMS for my facility for the past few months. Agilents 6545XT is a frontrunner for our intended applications, but we&#039;re also considering the Revident as a more future-proofed option. I am aware there has been no official announcement of a successor to the XT, but what does the community here think about how many years are left before this happens? Edit: should mention we&#039;re looking at H1 2027 purchase so whatever lifetime the XT has today, subtract 1 year from that. submitted by \/u\/TheProudCanadian [link] [comments]<\/div><\/li><li class='wp-block-rss__item'><div class='wp-block-rss__item-title'><a href='https:\/\/www.reddit.com\/r\/analyticalchemistry\/comments\/1sm9iaz\/pfas_in_drinking_water\/'>PFAS in drinking water !?<\/a><\/div><time datetime=\"2026-04-15T15:33:19-05:00\" class=\"wp-block-rss__item-publish-date\">April 15, 2026<\/time> <span class=\"wp-block-rss__item-author\">by \/u\/alchemicdpak<\/span><div class=\"wp-block-rss__item-excerpt\">submitted by \/u\/alchemicdpak [link] [comments]<\/div><\/li><li class='wp-block-rss__item'><div class='wp-block-rss__item-title'><a href='https:\/\/www.reddit.com\/r\/analyticalchemistry\/comments\/1skc9iz\/sample_stuck_in_xcalibur_sequence\/'>Sample Stuck in Xcalibur Sequence<\/a><\/div><time datetime=\"2026-04-13T14:20:40-05:00\" class=\"wp-block-rss__item-publish-date\">April 13, 2026<\/time> <span class=\"wp-block-rss__item-author\">by \/u\/Training-Resist-2745<\/span><div class=\"wp-block-rss__item-excerpt\">submitted by \/u\/Training-Resist-2745 [link] [comments]<\/div><\/li><\/ul>\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity is-style-wide\"\/>\n\n\n\n<h4 class=\"wp-block-heading\">Related Feeds<\/h4>\n\n\n<ul class=\"su-siblings\"><li class=\"page_item page-item-2707\"><a href=\"https:\/\/kermitmurray.com\/msblog\/links\/social-feeds\/reddit-feeds\/reddit-r-genomics\/\">Reddit r\/genomics<\/a><\/li>\n<li class=\"page_item page-item-2473\"><a href=\"https:\/\/kermitmurray.com\/msblog\/links\/social-feeds\/reddit-feeds\/reddit-r-massspectrometry\/\">Reddit r\/massspectrometry<\/a><\/li>\n<li class=\"page_item page-item-2705\"><a href=\"https:\/\/kermitmurray.com\/msblog\/links\/social-feeds\/reddit-feeds\/reddit-r-metabolomics\/\">Reddit r\/metabolomics<\/a><\/li>\n<li class=\"page_item page-item-2499\"><a href=\"https:\/\/kermitmurray.com\/msblog\/links\/social-feeds\/reddit-feeds\/reddit-r-proteomics\/\">Reddit r\/proteomics<\/a><\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Related Feeds<\/p>\n","protected":false},"author":1,"featured_media":2498,"parent":2738,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-2733","page","type-page","status-publish","has-post-thumbnail","hentry","entry"],"_links":{"self":[{"href":"https:\/\/kermitmurray.com\/msblog\/wp-json\/wp\/v2\/pages\/2733","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/kermitmurray.com\/msblog\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/kermitmurray.com\/msblog\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/kermitmurray.com\/msblog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/kermitmurray.com\/msblog\/wp-json\/wp\/v2\/comments?post=2733"}],"version-history":[{"count":3,"href":"https:\/\/kermitmurray.com\/msblog\/wp-json\/wp\/v2\/pages\/2733\/revisions"}],"predecessor-version":[{"id":2747,"href":"https:\/\/kermitmurray.com\/msblog\/wp-json\/wp\/v2\/pages\/2733\/revisions\/2747"}],"up":[{"embeddable":true,"href":"https:\/\/kermitmurray.com\/msblog\/wp-json\/wp\/v2\/pages\/2738"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/kermitmurray.com\/msblog\/wp-json\/wp\/v2\/media\/2498"}],"wp:attachment":[{"href":"https:\/\/kermitmurray.com\/msblog\/wp-json\/wp\/v2\/media?parent=2733"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}